Pubblicazioni
2025
Rinaldi F., Balboni B., Varignani G., Milordini G., Marotta R., Girotto S., Cavalli A.
An integrative structural study of RAD52, an emerging target in anticancer drug discovery
XXIX National Meeting on Medicinal Chemistry of the Italian Chemistry Society
Poster
Conference
2025
Rinaldi F., Franco P., Veronesi M., Romeo E., Bresciani V., Varignani G., Catalano F., Bernetti M., Masetti M., Langer J. D., Girotto S., Cavalli A.
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination
Research Square
Article
E-print Archive
2025
Bresciani V., Rinaldi F., Franco P., Girotto S., Cavalli A., Langer J. D., Masetti M., Bernetti M.
Dissecting the RAD51-BRC4 Interaction Landscape through Integrative Molecular Simulations and Experimental Biophysics
Journal of Chemical Information and Modeling
Article
Journal
2025
Rinaldi F., Balboni B., Marotta R., Girotto S., Cavalli A.
Elucidating RAD52 architecture through an integrated structural biology approach
51st Meeting of the Italian Crystallographic Association
Poster
Conference
2025
Bresciani V., Rinaldi F., Franco P., Girotto S., Cavalli A., Langer J. D., Masetti M., Bernetti M.
Integrating computational and experimental biophysics reveals novel insights into the RAD51-BRC4 interaction
BiorXiv
2025
Rinaldi F., Bresciani V., Franco P., Veronesi M., Bernetti M., Masetti M., Langer J., Cavalli A., Girotto S.
Probing the BRC repeats RAD51 interaction by integrating computational and experimental biophysics
The 49th FEBS Congress, vol. 15, pp. 461
2025
Rinaldi F., Bernetti M., Bresciani V., Veronesi M., Masetti M., Girotto S., Cavalli A.
The mechanistic understanding of the BRCA2-RAD51 interaction: an integrated structural biophysics study
Mammalian DNA Repair Gordon Research Seminar: Unraveling the Intricacies of DNA Repair in the Context of Chromatin and Genome Organization
Poster
Conference
2025
Rinaldi F., Bernetti M., Bresciani V., Veronesi M., Masetti M., Girotto S., Cavalli A.
The mechanistic understanding of the BRCA2-RAD51 interaction: an integrated structural biophysics study
Mammalian DNA Repair Gordon Research Conference: DNA Repair: Fundamental Mechanisms and Human Biology
Poster
Conference
2025
Rinaldi F., Girotto S.
Understanding how structure shapes the architecture of homologous recombination
Current Opinion in Structural Biology, vol. 95
2024
Bagnolini G., Poppi L., Previtali V., Ferrandi G., Rinaldi F., Girotto S., Hirsch A.K.H., Roberti M., Cavalli A.
A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery
National Congress of the Italian Chemistry Society 2024
Poster
Conference
2024
Myers S.H., Poppi L., Rinaldi F., Veronesi M., Ciamarone A., Previtali V., Bagnolini G., Schipani F., Ortega Martinez J.A., Girotto S., Di Stefano G., Farabegoli F., Walsh N., De Franco F., Roberti M., Cavalli A.
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer
European Journal of Medicinal Chemistry, vol. 265
2024
Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A.
An integrated structural approach reveals novel insights on the BRCA2 - RAD51 interaction
EMBO Practical Course on Small Angle Neutron and X-ray Scattering from biomacromolecules in solution
Poster
Conference
2024
Balboni B., Marotta R., Rinaldi F., Milordini G., Varignani G., Girotto S., Cavalli A.
An integrative structural study of the human full-length RAD52 at 2.2 Å resolution
Communications Biology, vol. 7, (no. 1)
2024
Bresciani V., Rinaldi F., Bernetti M., Masetti M.
Combining computational and experimental methods to characterize the RAD51-BRC repeats interaction
The 4th Masbic Annual Symposium
Poster
Conference
2024
Bresciani V., Rinaldi F., Bernetti M., Masetti M.
Elucidating the RAD51-BRC repeats interaction by integrating computational and experimental approaches
Summer School on Biomolecular Simulations
Poster
Conference