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Teresa Pellegrino Write a Message

Senior Researcher Tenured
Tenured Team Leader

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+39 010 71781 730

About

1. Personal Information                                                 

Date prepared: 15/02/2016

Name: Teresa Pellegrino

Office address:  Istituto Italiano di Tecnologia

via Morego 30, Genoa,

16163 Italy

eMail:  teresa.pellegrino @iit.it

 

 

RESEARCH INTERESTS

Preparation, characterization and biomedical applications of nanostructured materials made of entirely inorganic or organic-inorganic materials in which various components, having different properties (such as optical, chemical, and magnetic) are properly tailored and combined into single nano-objects.

2. Education

2000       M.S. in Chemistry, Department of Chemistry, University of Bari, Italy

2005       Ph.D. in Chemistry, Department of Pharmacology, University of Bari, Italy

3. Scientific Carrier

3.1 Post-doctoral Training:

2004-2010                                            Staff Scientist at the National Nanotechnology Lab in Lecce (Italy)

3.2 Academic appointments:

 

February 2014-current                  Tenured Team leader of the group Nanomaterials for Biomedicine at the Drug Discovery Facility at the Italian Institute of Technology in Genova (Italy)

February 2010- February 2014   Permanent staff scientist at the Nanoscience Institute of CNR at the National Nanotechnology Lab in Lecce (Italy)

 

 

3.3 Visiting scientist:

 

10/1999-10/2000                              Internship in an Analytical Chemistry Laboratory, University of Bari (Italy)

 

07/2001-02/2003                             Visiting Student, at Department of Chemistry, Prof. P. Alivisatos group, University of California, Berkeley

 

03/2003-08/2004                             Marie Curie Fellowship at the Center for Nanoscience, Prof. W.J. Parak group, Munich (Germany)

 

 4. Professional activities

4.1 Teaching Expertise

 

2015                            PhD School IIT, Genoa, Italy 8 hours course on the topic: “Nanoparticles for Biomedical Applications”

2007                            Scuola Superiore Isufi, Lecce, Italy-. 20 hours course: "Fundamentals of organic chemistry"

2006                            Scuola Superiore Isufi, Lecce, Italy: 20 hours course and 80 hours lab class on the topic: "Quantum dot and Gold nanoparticles: synthesis, surface modification and cellular studies "

2006                            Sanofi-Aventis S.p.a, Brindisi, Italy: 8 hours course on the topic: "Nanomaterials and Nanotechnology"

2001                            Department of mechanical Engineering, University of Bari, Italy: 30 hours Lab course on: "General and Inorganic Chemistry"

4.2 Tutoring expertise 

-People currently working in my group: ■Alessia Petrelli: Post Doc on Cariplo project (2015-2016); ■ Tommaso Avellini: Post Doc on Airc project (2014-2016); ■ Markus Barthel: Post Doc on internal IIT funds (2014-2016); ■ Dina Niculaes: Marie Curie PhD student at IIT on magneticfun project (2013-2016); ■ Maria Elena Materia: Fellow on IIT internal funds (2015-2016); ■ Aidin Lak: Post Doc on internal IIT funds (2015-2016); ■ Preethi Bala, Thanh Binh, Marco Cassani, Niccolò Silvestri: PhD students

- Former members of my group: ■Ralph Sperling: Undergraduate student program at Center for Nanoscience, Munich, Germany (2005) ■Luca Palmirotta: Undergraduate student program at CNR-INFM (2006) ■Riccardo DiCorato: Undergraduate (2006) and graduate program (2007-2008) at CNR-INFM  ■Angela Fiore: :PhD student program at CNR-INFM (2006-2008) ■Alessandra Quarta: PhD student program at CNR-INFM (2006-2008) ■Maria Ada Malvindi: PhD student program at CNR-INFM (2008) ■Annagrazia Monteduro: Undergraduate student program at CNR-INFM (2008) ■Philomena Piacenza: research assistant (2007-2009) at CNR-INFM■Smitri Rheka Deka: Post Doc fellow (2008) at CNR-INFM and Post-Doc fellow at IIT (2009) ■ Manuel Pernia: Post-Doctoral Fellow at IIT (2010-2012) ■ Nadja Carola Bigall: Post-Doctoral Fellow at IIT (2009-2012) ■ Domenico Palumberi: Post-Doctoral Fellow at IIT (2009-2010) ■ Graziano Antico: Junior Technician at NNL Nanoscience Institute of CNR (2010-2012) ■ Hamilton Kakwere: Post-Doctoral Fellow at IIT (2012-2013) ■ Alberto Curcio: PhD student program at IIT (2010-2013) ■ Andreas Riedinger: PhD student program at IIT (2010-2013) ■ Pablo Guardia: Post-Doctoral Fellow at IIT (2009-2013) ■ Maria Elena Materia: PhD student at IIT (2012-2014) ■ Sara Guerrieri: PhD student at IIT (2012-2014)

4.3 Organization of conference/symposia

 

2014          Organizer of Minicolloquim entitled: "The life-cycle of nanomaterials in the (bio)environment: impact on physical properties and toxicity issues" at Condensed Matter in Paris

2013          Chair of the final International workshop of the Magnifyco project, Barcelona

2013      Organizer of Symposium Q at the e-MRS meeting: "Bionanomaterials for imaging, sensing and actuating", Nice, France

2011          Organizer of the Symposium O at the e-MRS meeting:“Bionanomaterials for imaging, sensing and  actuating”, Strasbourg, France

2011      Organizer of the International Workshop on “Magnetic Nanocontainers for Combined Hyperthermia and Controlled Drug Release” at the Italian Institute of Technology, Genoa, Italy

4.4 Referee for several International Journals

JACS, Advanced Materials, Advanced Functional Materials, Nature Materials, Nature Nanotechnology, Nano Letters, Angewandte Chemie, Small, Langmuir, Journal of Materials Chemistry

4.5 Committee and other services

2015- External expert member for the commission of the PhD thesis defence of Dr. Nadia Licciardello (thesis Title: design, synthesis and functionalization of ultrasmall nanoparticles for bioimaging), CNRS Strasbourg, France

 2014- National habilitation as Full Professor for the area of "Fundamental of Chemical Science and Inorganic System for the period (starting on 23/12/2013 and ending on 23/12/2017)

2013 - External expert member for the commission of the PhD thesis defence of Dr. Juan Comenge (thesis Title: Gold NPs as drug delivery agents; detoxifying the antitumoral drug cisplatinum), Institut Catala de Nanotecnologia, Spain

2009 - External expert member for the commission of the PhD thesis defence of Dr. Elena Taboada Cabellos (thesis title: Synthesis of ϒ-Fe2O3-SiO2 composite nanoparticles targeting magnetic resonance imaging and magnetic hyperthermia applications ) at Universitat Autonoma de Barcelona, Spain

2008 - Public presentation entitled “Art and Science: TEM images, Colours and Design”, at the “Nano-Tech Design dispositivi periferici” event held in Lecce (Italy) at Manifatture Knos exposition center

2009 - Coordinated design and production of the annual calendar of the Institute National Nanotechnology Laboratory of CNR, by artistically modifying TEM and SEM pictures.

 

4.6 Panel Evaluator, Proposal Reviewer

2012              Croatian Science Foundation: Proposal Reviewer

2012              Molecular Foundry, LBL Berkeley: Proposal Reviewer

2008-2009   Swiss National Science Foundation: Proposal Reviewer

4.7 Invited Seminars/Lectures/Colloquia, conference presentations and teaching Expertise: 32 international conference presentations (26 invited talks), 18 invited seminars, 5 invited talks at international summer schools. During the last three years, I have been regularly invited to the spring eMRS meeting to present my work and to the International Cell Model System summer school in Rome. See my personal webpage at iit website for a complete list of talks. http://www.iit.it/en/nach-people/teresa-pellegrino.html

 

Invited Seminars/Lectures/Colloquia, conference presentations

2013 talks:

- “Development of nanomaterials for intelligent drug delivery and cancer therapy”, CNRS (Strasburg, France), May 30, 2013

-“Development of nanomaterials for intelligent drug delivery and cancer therapy”, Workshop Italian-Japan, (Tokyo, Japan), April 15, 2013,

- “Highlighting some MAGNIFYCO project results: iron oxide nanocubes as heat mediators for combining hyperthermia treatment with drug delivery” NPMED International Conference, 2013, (Bresso, Mi Italy), June 20, 2013

- “Highlighting some MAGNIFYCO project results: iron oxide nanocubes as heat mediators for combining hyperthermia treatment with drug delivery” , Joint European Magnetic Symposium, 2013, (Rhodes Greece), August 28, 2013

- “Highlighting some MAGNIFYCO project results: iron oxide nanocubes as heat mediators for combining hyperthermia treatment with drug delivery”, Pharma Process, Fira de Barcelona, (Barcelona Spain), 30 October, 2013

- “Local Temperature Probing and Remotely Controlled Drug Delivery Based on an Azo-functionalized Iron Oxide Nanoparticles or a Thermo-responsive Shell Upon Alternating Magnetic Field Exposure”, MMM58, CONFERENCE ON MAGNETISM AND MAGNETIC MATERIALS,  Denver ( Colorado USA), November 7, 2013

- “Development of nanomaterials for intelligent drug delivery and cancer therapy”, University of Palermo, Department of Surgery Disciplines, Palermo Italy, November 21, 2013  

 

 

List of selected conferences and schools from 2009-2011

1. International Conference of Hybrid Materials, Tours, (France) March 17th 2009 (invited)

2.         European Science Foundation Exploratory Workshop, Sintra, (Portugal), August 31st 2009 (invited)

3. International conference on magnetic Carriers, Rostock (Germany), May 27th, 2010,

4. Fourth Summer School by the Erasmus Mundus Course, Hyères (France)  July 23rd, 2010, (invited)

5. X Nano2010, Rome (Italy), September 16th, 2010, (invited)

6. NanotechItaly 2010 Venice (Italy), October 22nd, 2010, (invited)

7. SPIE conference, San Francisco, California (USA), January 24, 2011, (invited)

8. 8th International Conference NN11, Thessaloniki (Greece), 12-15 July 2011, (invited)

9. Swedish-Italian workshop on Nanoscience and Medical technology, YKI, Stockholm (Sweden), 29-30 September, 2011, (invited)

 

Invited talks prior to 2009

  • ''A novel quantum dot based invasion assay for the study of the cell motility', February 23th, 2003, CeNS Winterschool Mauterndorf, Austria
  • ''A novel quantum dot based invasion assay for the study of the cell motility', May 23th, 2003, International Symposium, Jena, Germany
  • "Colloidal Nanocrystals:Synthesis, Surface Functionalization and Biological Applications", October 27th, 2006, Department of Organic Chemistry, University of Sevilla, Spain
  • "Development of Luminescent Quantum Dot-GSH Conjugate for Targeting Hydra Vulgaris". September 15th, 2006, SA-NANO meeting, Lecce, Italy
  • "Functionalization of Nanoparticles", November 15th, 2006, Molecular Foundry Workshop "Italy-USA FIRB Bilateral project", Berkeley, CA, USA
  • "Nanoparticles, Physical and Chemical Properties,Synthesis and Biomedical Applications of Quantum Dots" November 26th, 2006, Meeting of the Italian Society of Chemistry, Cosenza, Italy
  • ''Functionalization of Nanoparticles", February 1st, 2007, Department of Chemistry, University of Aveiro, Portugal
  • "Bio-functionalization of nanoparticles and their use in biological applications", March 8th, 2007, Molecular Foundry, Berkeley, CA, USA
  • "Biofunctionalization of nanoparticles and their use in biological applications", May 29, 2007, CNR, Bologna, Italy
  • ''Synthesis, Biofunctionalization and Use of Nanoparticles in Biological Applications", June 14 2007, Istituto di Cibernetica, Pozzuoli, Italy
  • "Magnetic nanoparticles: Synthesis, Bio-functionalization and their use in biological applications", June 25 , 2007, International Work-shop on Magnetic Nanoparticles, University of Madrid, Spain
  • "Magnetic-fluorescent nanoparticles and their applications in biology", September 9, 2008, CNR, Bologna, Italy
  • "Magnetic-fluorescent nanoparticles and their applications in biology" Intern. Summ. School "Colloidal Nanoparticles: from synthesis to Biological Applications", September 15-17 2008, Marburg (Germany)
  • "Multi-functional nanocomposites for cellular studies and cell sorting applications", November 10, 2008, Delft University of Technology, Kavli Institute of NanoScience, University of Delft,( Netherlands)
  • "Multifunctional Nanocomposites for cellular studies", January 19, 2009, Italian Institute of Tumour, Milan (Italy)
  • "Novel Inorganic hybrid nanostructures for biomedical applications" March 17, 2009, International Conference of Hybrid Materials, Tours, (France)
  • "Novel Inorganic hybrid nanostructures for biomedical applications" May 20, 2009, Ceramic, Cells and Tissues 12th Annual Conference, Faenza (Italy)

 

Other Interests: Clay pottery works, water colour and oil painting.

 

Graduate Advisors

  • Prof. Giovanni Natile, University of Bari, Italy
  • Prof. Paul Alivisatos, University of California, Berkeley, USA
  • Prof. Prof. W. J. Parak Center for Nanoscience, Munich, Germany

 

5. Scientific output

5.1 Summary. Since my first publication in 2002, so far I have published in total 91 papers in international journals (5 invited reviews, 5 as a first author and 39 out of 91 as corresponding author).

See also http://scholar.google.it/citations?user=ssxCVUAAAAAJ&hl=it  or my personal webpage at iit website for the full list of talks. I was invited to write review articles for several journals (among them Chemical Society Reviews, IEEE Transaction on Nanobioscience, Pharmacological Research, Nanoscale) and 7 book chapters. I also have 5 patents

 

5.2 Patents

Issued Patents (+ 2 pending)

“Chip a trasduzione elettrica per analisi genomiche/proteomiche” (“A nanoelectrode-based chip for the detection of single biorecognition events for genomics and proteomics applications”), G. Maruccio, E. Primiceri, P. Marzo, V.Arima, R.Krahne, T.Pellegrino, A. Della Torre, F. Calabi, R. Cingolani, R. Rinaldi, Italian patent number: TO2007A000341 (15-05-2007).

“Method for separating nanoparticles with a controlled number of active groups” W. H.-S. Chang, J. K.-J. Li, R. A. Sperling, T. Pellegrino, W. Parak, (US Patent 207/0134679), (14-07-2007).

“Nanocapsule colloidali magnetiche fluorescenti:procedimento per la loro preparazione e loro impiego in saggi di selezione cellulari”, T. Pellegrino, R. Di Corato, P. Piacenza, L. Manna, R. Cingolan, Italian patent application number: TO2009A000169 (patent filed on 06-03-2009).

“Nanocristalli di ferrite e loro usi” Patent Application n.ITTO2012A000306, Filing date: April 6, 2012, Inventors: Pablo Guardia, Andreas Riedinger, Simone Nitti, Teresa Pellegrino, Liberato Manna, Roberto Cingolani.

“Sistema nanoparticellare sensibile al calore” Patent Application n.TO2013A000065, Filing date: January 28, 2013, Inventors: Andreas Riedinger, Teresa Pellegrino, Pablo Guardia, Alberto Curcio, Roberto Cingolani, Liberato Manna

5.3 Book Chapters

“Measuring Cell Motility Using Quantum Dot Probes” Weiwei Gu; Teresa Pellegrino; Wolfgang J. Parak; Rosanne Boudreau; Mark A. Le Gros; A. Paul Alivisatos; Carolyn A. Larabell, (Quantum Dots, Applications in Biology, 2007 (Clifton, NJ), Chapter 11, pp. 125 - 132) .

‘Fluorescent Nanocrystals and Proteins in Nanobioelectronics - for Electronics, Biology  and Medicine’, P. P. Pompa, T. Pellegrino and L. Manna,ed. by Andreas Offenhäusser and Ross Rinaldi, Springer 2009.

‘Quantum dot Nanoparticles: Properties, Surface Functionalization, and their applications in biosensoring and imaging’, in ‘Nanostructured Materials for Biomedical Applications’, Ragusa, A. Zacheo, T. Pellegrino and L. Manna, Edited by M. C. Tan, Transworld Research Network, Kerala, India, 2010.

“Quantum Dots Designed For Biomedical Applications” A. Ragusa, A. Zacheo, A. Aloisi, and T. Pellegrino, Chapter 10, Edited by  C Altavilla and S. Ciliberto, Taylor & Francis Group USA, October 2010

“Immunochemistry, Electron Tomography and Energy Dispersive X-Ray Spectroscopy (EDXS) on Cryosections of Human Cancer Cells Doped with Stimuli Responsive Polymeric Nanogels Loaded with Iron Oxide Nanoparticles”  Roberto Marotta, A. Falqui, A. Curcio, A. Quarta, and Teresa Pellegrino, in Nanomaterial Interfaces in Biology, Chapter 14, Edited by Kimberly Hamad-Schifferli, and Paolo Bergese, 2013, XIV, 302 p. a product of Human Press, Springer

Antibody -Functionalized Inorganic NPs: Mimicking Nature for Targeted Diagnosis and Therapy”; A Quarta, L Manna, T Pellegrino; Book Title: Bioinspired Approaches for Human-Centric Technologies for Springer, 2014, Editor: R. Cingolani, book Chapter N-.1, 1-28“Magnetic Nanoparticles for Magnetic Hyperthermia and Controlled Drug Delivery”; Pablo Guardia, Andreas Riedinger, Hamilton Kakwere, Florence Gazeau, and Teresa Pellegrino; Book Title: Bio- and bioinspirednanomaterials, Wiley , Editors: Daniel Luis-Molina, Fernando Novio, In press, it will be published in September 2014,

 

5.4 Full list of Papers in peer-reviewed journals (* indicate my corresponding papers):

 

2016

J Kolosnjaj-Tabi, “Biotransformations of magnetic nanoparticles in the body”, J Kolosnjaj-Tabi, Nano Today, in press doi:10.1016/j.nantod.2015.10.001,  (2016)

A Espinosa, “The Duality of Iron Oxide Nanoparticles in Cancer Therapy: Amplification of Heating Efficiency by Magnetic Hyperthermia and Photothermal Bimodal Treatment”, ACS NANO, in press, DOI: 10.1021/acsnano.5b07249 (2016)

Sathya A., “CoxFe3-xO4 Nanocubes for Theranostic Applications: Effect of Cobalt Content and Particle Size“, Chemistry of Materials, in press, DOI: 10.1021/acs.chemmater.5b04780 (2016)*

2015

B. Spagnolo , "Three-dimensional cage-like microscaffolds for cell invasion studies", Scientific Reports, 5, p 10531 doi:10.1038/srep10531, (2015)

A. Salvetti et al., In vivo biocompatibility of boron nitride nanotubes: Effects on stem cell biology and tissue regeneration in planarians, Nanomedicine, Pages 1-12 doi:10.2217/nnm.15.46, (2015)

Bigall NK et al. "Hollow Iron Oxide Nanoparticles in Polymer Nanobeads as MRI Contrast Agents", J. Phys. Chem. C, (2015), 119 (11), pp 6246–6253, DOI: 10.1021/jp508951t*

Materia et al. "Mesoscale Assemblies of Iron Oxide Nanocubes as Heat Mediators and Image Contrast Agents", Langmuir, 2015, 31 (2), pp 808–816; DOI: 10.1021/la503930s*

S. Carregal-Romero et al., "Magnetically triggered release of molecular cargo from iron oxide nanoparticle loaded microcapsules", DOI: 10.1039/C4NR04055D, Nanoscale, 2015, 7, 570-576*

Quarta, A. et al. Targeting FR-expressing cells in ovarian cancer with Fab-functionalized nanoparticles: a full study to provide the proof of principle from in vitro to in vivo, Nanoscale 2015, 7, 2336-2351.*

Wang, S. et al. Plasmonic Copper Sulfide Nanocrystals Exhibiting Near-Infrared Photothermal and Photodynamic therapeutic Effects, ACS Nano 2015, 9 (2), pp 1788–1800*

Kakwere H et al., "Functionalization of Strongly Interacting Magnetic Nanocubes with (Thermo)Responsive Coating and Their Application in Hyperthermia and Heat-Triggered Drug Delivery", ACS Appl. Mater. Interfaces, 2015, 7 (19), pp 10132–10145, DOI: 10.1021/am5088117*

Akkerman, Q. A. et al. From Binary Cu2S to Ternary Cu–In–S and Quaternary Cu–In–Zn–S Nanocrystals with Tunable Composition via Partial Cation Exchange,ACS Nano 2015, 9, 521-531.

Bartelmess J. et al., Non-covalent functionalization of carbon nano-onions with pyrene–BODIPY dyads for biological imaging, RSC Adv., 2015,5, 50253-50258,

Jelena Kolosnjaj-Tabi et al.The One Year Fate of Iron Oxide Coated Gold Nanoparticles in Mice, ACS Nano, 2015, 9 (8), 7925-7939,

Yi Xie, Nanoscale Transformations in Covellite (CuS) Nanocrystals in the Presence of Divalent Metal Cations in a Mild Reducing Environment; Chemistry of Materials, 2015, 27 (21), pp 7531–7537,

Riedinger A, Avellini T., Curcio A. et al. Post-Synthesis Incorporation of 64Cu in CuS Nanocrystals to Radiolabel Photothermal Probes: A Feasible Approach for Clinics, Journal of the American Chemical Society, 2015137 (48), 15145-15151*

Barthel M et al., Synthesis of Highly Fluorescent Copper Clusters Using Living Polymer Chains as Combined Reducing Agents and Ligands, 2015, ACS Nano, DOI: 10.1021/acsnano.5b04270*

2014

"One pot synthesis of monodisperse water soluble iron oxide nanocrystals with high values of specific absorption rate" Pablo Guardia, Andreas Riedinger, Simone Nitti, Giammarino Pugliese, Sergio Marras, Alessandro Genovese, Maria Materia, Christophe Lefevre, Liberato Manna, Teresa Pellegrino, (2014) Journal of Materials Chemistry B, 2, 4426-4434 * Highligthed by the Journal with the Back Cover assigned“ Nanoparticles for Imaging, Sensing, and Therapeutic Intervention” Lara K. Bogart, Genevieve Pourroy , Catherine J. Murphy, Victor Puntes , Teresa Pellegrino , Daniel Rosenblum , Dan Peer, and Raphaël Lévy; (2014) Acs Nano; 8 (4), 3107-3122; DOI: 10.1021/nn500962q"Magnetic hyperthermia efficiency in the cellular environment for different nanoparticle designs;" R Di Corato, A Espinosa, L Lartigue, M Tharaud, S Chat, T Pellegrino, Christine Ménager, Florence Gazeau, Claire Wilhelm; Biomaterials 35 (24), 6400-6411"Heat-Generating Iron Oxide Nanocubes: Subtle “Destructurators” of the Tumoral Microenvironment" J Kolosnjaj-Tabi, R Di Corato, Lénaic Lartigue, Iris Marangon, Pablo Guardia, Amanda KA Silva, Nathalie Luciani, Patrice Flaud, Olivier Clément, Jaykrishna V Singh, Paolo Decuzzi, Teresa Pellegrino, Claire Wilhelm, Florence Gazeau, ACS nano, 2014, 8 (5), 4268–42832013 "Dumbbell Nanocrystals. with Tunable Composition by Reduction of Covellite Nanocrystals with Cu+ Ions", Xie, Y.; Riedinger, A.; Prato, M.; Casu, A.; Genovese, A.; Guardia, P.; Sottini, S.; Sangregorio, C.; Miszta, K.; Ghosh, S.; Pellegrino, T.; Manna, L. ( J. Am. Chem. Soc. 2013, 135, 17630−17637).

“Colloidal Ordered Assemblies in a Polymer ShellA Novel Type of Magnetic Nanobeads for Theranostic Applications” N. C Bigall , C. Wilhelm , M. Beoutis , M. Garcia-Hernandez , A. Ali Khan , C. Giannini , A. Sanchez-Ferrer , R. Mezzenga , M. E. Materia , M. Angel Garcia , F. Gazeau , A. M Bittner , L. Manna , and T. Pellegrino (Chemistry of Materials, 2013, 25, 1055) *

“Magnetic properties of iron oxide nanoparticles prepared 3 by seeded-growth route” A. Espinosa, A. Munoz-Noval, M. Garcıa-Hernandez, A. Serrano, J. Jimenez de la Morena, A. Figuerola, A. Quarta, T. Pellegrino, C. Wilhelm, M. A. Garcıa, (Journal of Nanoparticle Research, 15 (4), 1-132013, DOI:10.1007/s11051-013-1514-8)

“Biodegradation of Iron Oxide Nanocubes: High Resolution In Situ Monitoring” Lartigue, L.; Alloyeau, D.; Kolosnjaj-Tabi, J.; Javed, Y.; Guardia, P.; Riedinger, A.; Pechoux, C.; Pellegrino, T.; Wilhelm, C.; Gazeau, F., ACS Nano 2013, 7(5), 3939)

“Sub-Nanometer Local Temperature Probing and Remotely Controlled Drug Release Based on Azo-Functionalized Iron Oxide Nanoparticles” A. Riedinger, P. Guardia, A. Curcio, M.A. Garcia, R. Cingolani, L. Manna, T.Pellegrino, , Nano Letters 2013, 13 (6), 2399*

"Cell-derived Vesicles as a Bioplatform for the Encapsulation of Theranostic Nanomaterials” K. A. Silva, R. Di Corato, N. Luciani, R. Losno, G. Pugliese, T. Pellegrino, F. Gazeau, C. Wilhelm ( 2013, Nanoscale 5 (23), 11374-11384 DOI: 10.1039/C3NR01541F), Highligthed by the Journal with the Front Cover assigned

2012

“Superparamagnetic cellulose fiber networks via nanocomposite functionalization" D. Fragouli, IS. Bayer, R. Di Corato, R. Brescia, G. Bertoni, C. Innocenti, D. Gatteschi, T. Pellegrino, R. Cingolani, A. Athanassiou, (Journal Of Materials Chemistry, 22 (4), 1662-1666 , 2012)

“Magnetic pH-responsive nanogels as multifunctional delivery tools for small interfering RNA (siRNA) molecules and iron oxide nanoparticles (IONPs)” A. Curcio, R. Marotta, A. Riedinger, D. Palumberi, A. Falqui, T. Pellegrino, (Chemical Communications, 48 (18), 2400-2402, 2012) *

“On the discrimination between magnetite and maghemite by XANES measurements in fluorescence mode”, A Espinosa, A. Serrano, A. Llavona, JJ. de la Morena, M. Abuin, A. Figuerola, T. Pellegrino, JF. Fernandez, M. Garcia-Hernandez, GR. Castro, MA. Garcia, (Measurement Science & Technology, 23 (1), 2012)

“Water-Soluble Iron Oxide Nanocubes with High Values of Specific Absorption Rate for Cancer Cell Hyperthermia Treatment” P. Guardia, R. Di Corato, L. Lartigue, C. Wilhelm, A. Espinosa, M. Garcia-Hernandez, F. Gazeau, L. Manna, and T. Pellegrino (ACS Nano, 6 (4), 3080-3091) *

“Polymer coated inorganic nanoparticles: tailoring the nanocrystal surface for designing nanoprobes with biological implications” A. Quarta, A. Curcio, H. Kakwere and T. Pellegrino (Nanoscale,4(11), 3319-3334, feature article) *

“Magnetophoresis at the nanoscale: tracking magnetic targeting efficiency of nanovectors” A. Andriola Silva, R. Di Corato, F. Gazeau, T. Pellegrino and C. Wilhelm (Nanomedicine, 7(11), 1713-1727, 2012)

“'Magnetic nanobeads decorated with silver nanoparticles as cytotoxic agents and photothermal probes” R. Di Corato, D. Palumberi, R. Marotta, M. Scotto, S. Carregal-Romero, P. Rivera-Gil, W. J Parak and T. Pellegrino (Small, 8 (17) 2731-2742) *

“Controlled Release of Doxorubicin Loaded within Magnetic Thermo-responsive Nanocarriers under Magnetic and Thermal Actuation in a Microfluidic Channel”, M. Pernia, A. Torti, A. Riedinger, R. La Fleur, D. Petti,R. Cingolani, R. Bertacco, T. Pellegrino (Acs Nano, 6(12), 10535, 2012) *

2011

“Water-repellent Cellulose Fiber Networks with Multifunctional Properties" I. Bayer, D. Fragouli, A.Attanasio, B. Sorce, G. Bertoni, R. Brescia, R. Di Corato, T. Pellegrino, M. Kalyva, S. Sabella, P. P. Pompa, R. Cingolani and A. Athanassiou (Applied Materials and Interfaces, 2011, 3(10), 4024, 2011)

“Magnetic Nanocarriers with Tunable pH Dependency for Controlled Loading and Release of Cationic and Anionic Payloads” Nadja C. Bigall, A. Curcio, M. Pernia Leal, A. Falqui, D. Palumberi, R. Di Corato, E. Albanesi, R. Cingolani and T. Pellegrino (Advanced Materials, 2011, 23(47), 5645, 2011) *

“Multiple functionalization of fluorescent nanoparticles for specific biolabeling and drug delivery of dopamine” M. A. Malvindi, R. Di Corato, A. Curcio, D. Melisi, M. G. Rimoli,C. Tortiglione, A. Tino, C. George, V. Brunetti, R. Cingolani, T. Pellegrino and A. Ragusa (Nanoscale, 2011 3(12), 5110)

“Magnetic nanobeads decorated by thermo-responsive PNIPAM shell as medical platforms for the efficient delivery of doxorubicin to tumour cells” S. R. Deka, A. Quarta, R. Di Corato, A. Riedinger, R. Cingolani and T. Pellegrino (Nanoscale, 3 (2), 619 - 629, 2011) *

“Multifunctional Nanobeads Based on Quantum Dots and Magnetic Nanoparticles – Synthesis and Cancer Cell Targeting and Sorting” R. Di Corato, N. Bigall, A. Ragusa, D. Dorf, A. Genovese, R. Marotta, L. Manna, and T. Pellegrino (ACS Nano, 5 (2) 1109-1121, 2011) *

“A Cast-Mold Approach to Iron Oxide and Pt/Iron Oxide Nanocontainers and Nanoparticles with a Reactive Concave Surface” C. George, D. Dorfs, G. Bertoni, A. Falqui, A. Genovese, T. Pellegrino, A. Roig, A. Quarta, R. Comparelli, M. L. Curri, R. Cingolani, and L. Manna (Journal of the American Chemical Society, 133 (7), pp 2205–2217, 2011)

“CdSe/CdS Semiconductor Quantum Rods as Robust Fluorescent Probes for Paraffin-Embedded Tissue Imaging” A. Zacheo, A. Quarta, A. Mangoni, P. P. Pompa, R. Mastria, M. Capogrossi, R. Rinaldi and T. Pellegrino (Transaction on NanoBioscience, 10 (3), pp. 209-215, 2011) *

“Correlating Magneto-Structural Properties to Hyperthermia Performance of Highly Monodisperse Iron Oxide Nanoparticles Prepared by a Seeded-Growth Route” M. Levy, A. Quarta, A. Espinosa, A. Figuerola, C. Wilhelm, M. Garcia-Hernandez, A. Genovese, A. Falqui, D. Alloyeau, R. Buonsanti, P. D. Cozzoli, M. A. Garcia, F. Gazeau and T. Pellegrino (Chemistry of Materials, 23 (18), 4170–4180, 2011)

“Charge Transport and Electrochemical Properties of Colloidal Greigite (Fe3S4) Nanoplatelets” A. Paolella, C. George, M. Povia, Y. Zhang, R. Krahne, M. Gich, A. Genovese, A. Falqui, M. Longobardi, P. Guardia, T. Pellegrino and L. Manna (Chemistry of Materials, 23 (16), 3762–3768, 2011)

“Nanohybrids” Based on pH-Responsive Hydrogels and Inorganic Nanoparticles for Drug Delivery and Sensor Applications" A. Riedinger, M. Pernia Leal, S. R. Deka, C. George, I. R. Franchini, A. Falqui, R. Cingolani, T. Pellegrino (Nano Letters, 11, 3136–3141, 2011) *

“Rod-shaped nanostructures based on super-paramagnetic nanocrystals as viscosity sensors in liquid " M. Allione, B. Torre, A. Casu, A. Faalqui, P. Piacenza, R. Di Corato, T. Pellegrino and A. Diaspro (Journal of Applied Physics, 110 (6), pp. 064907-1/064907-6)

“"Magnetic/Silica nanocomposites as dual-mode contrast agents for combined Magnetic Resonance Imaging and UltraSonography"M. A. Malvindi, A. Greco, F. Conversano, A. Figuerola, M. Corti, M. Bonora, A. Lascialfari, H. A. Doumari, M. Moscardini, R. Cingolani, G. Gigli, S. Casciaro, T. Pellegrino, and A. Ragusa (Advanced Functional Materials, 21 (13), 2548-2555, 2011)

2010

“From Iron Oxide Nanoparticles Towards Advanced Iron-Based Inorganic Materials Designed For Biomedical Applications” A.S. Figuerola, R. Di Corato, L.Manna and T. Pellegrino (Pharmacological Research, 62, 126-143, 2010) *

Acidic pH-responsive nanogels as cargo system for the simultaneously loading and release of short oligonucleotide and magnetic nanoparticles” S. Deka, A. Quarta, R. Di Corato, A. Falqui, L. Manna, R. Cingolani and T. Pellegrino, (Langmuir, 26 (12), 10315-10324, 2010) *

Silica nanoparticles for quantitative ultrasound molecular imaging and automatic tissue typing at conventional diagnostic frequencies” S. Casciaro, F. Conversano, A. Ragusa, M. A. Malvindi,R. Franchini, A. Greco, T. Pellegrino, G. Gigli. (Investigative Radiology, 45(11), 715-724, 2010)

2009

"An ab initio study of the CoPt3-Au interface: implications on the growth of colloidal CoPt3-Au nanocrystal heterodimers" L. Chiodo, F. Della Sala, T. Pellegrino, R. Cingolani, L. Manna (Journal of Physics: Condensed Matter, 2009, 21, 1-13, (http://www.iop.org/EJ/abstract/0953-8984/21/1/015001/)

‘CdSe/CdS/ZnS double shell nanorods with high photoluminescence efficiency and their exploitation as bio-labeling probes’, S. Deka, A. Quarta, M. G. Lupo, A. Falqui, S. Boninelli, C. Giannini, G. Morello, M. De Giorgi, G. Lanzani, C. Spinella, R. Cingolani, T. Pellegrino and L. Manna, (Journal of the American Chemical Society), 2009, 131 (8), 2948–2958. *

‘Magnetic-Fluorescent Colloidal Nano-Beads: Preparation and Exploitation in Cell Separation Experiments’, R. Di Corato, P. Piacenza, M. Musarò, R. Buonsanti, P. D. Cozzoli, M. Zambianchi, G. Barbarella, R. Cingolani, L. Manna and T. Pellegrino, (Macromolecular Bioscience, 2009, 9, 952–958). *

“Fluorescent Nanocrystals Reveal Regulated Portals of Entry into and Between the cells of Hydra C. Tortiglione, A. Quarta, M. A. Malvindi, A. Tino, T. Pellegrino, (Plos One, 2009, 4 (issue 11), e7698, 1-14)

“A nanoelectrode-based biosensor for the detection of single biorecognition events” G. Maruccio, E. Primiceri, P. Marzo, V. Arima, T. Pellegrino, R. Krahne, A. Della Torre, R. Cingolani and R. Rinaldi, (Analyst, 2009, 134, 2458-2461)

Copper-triggered aggregation of ubiquitin” F. Arnesano, S. Scintilla, V. Calò, E. Bonfrate, C. Ingrosso, M. Losacco, T. Pellegrino, E. Rizzarelli, G. Natile,(Plos One, 2009, 4 (issue 9), e7052, 1-11)

“A Bio-conjugation of rod-shaped fluorescent nanocrystals for efficient targeted cell labelling” A.Quarta, A. Ragusa, S. Deka, C. Tortiglione, A. Tino, R. Cingolani and T. Pellegrino, (Langmuir, 2009, 25 (21), 12614-12622) *

2008

"Rod Shaped Nanocrystals Elicit Neuronal Activity In Vivo " M. A. Malvindi, L. Carbone, A. Quarta, A. Tino, L. Manna, T. Pellegrino , C. Tortiglione, (Small, 2008, 4(10), 1747–1755)

“Multifuctional Nanostructures Based on Inorganic Nanoparticles and Oligothiophenes and their Exploitation for Cellular Studies” A. Quarta, R. Di Corato, L. Manna, S. Argentiere, R Cingolani, G. Barbarella and T. Pellegrino, (Journal of the American Chemical Society, 2008,130,10545-10555) *

“Water solubilization of hydrophobic nanocrystals by means of poly(maleic anhydride-alt-1-octadecene)” R. Di Corato, A. Quarta, P. Piacenza, A. Ragusa, A. Figuerola, R. Buonsanti, R. Cingolani, L. Manna and T. Pellegrino (Journal of Materials Chemistry 2008, 18, 1991-1996) *

"One-pot Synthesis and Characterization of Size-Controlled Bimagnetic FePt-Iron Oxide Heterodimer Nanocrystals" Figuerola, A.; Fiore, A.; Di Corato, R.; Falqui, A.; Giannini, C.; Micotti, E.; Lascialfari, A.; Corti, M.; Cingolani, R.; Pellegrino, T.; Cozzoli, P. D.; Manna, L. (Journal of the American Chemical Society 2008, 130, 1477-1487)

"Magnetic properties of novel superparamagnetic MRI contrast agents based on colloidal nanocrystals" M. Corti, A. Lascialfari, E. Micotti, A. Castellano, M. Donativi, A. Quarta, P. D. Cozzoli, L. Manna, T. Pellegrino, C. Sangregorio (Journal of Magnetism and Magnetic Materials 2008, 18, 1991-1996))

2007

“Fluorescent-magnetic hybrid nanostructures: preparation, properties and applications in biology” A Quarta, R. Di Corato, L. Manna, A. Ragusa and T. Pellegrino,(Transaction on NanoBioscience, 2007, 6, 298-308) topical review*

“Synthesis and biological assay of GSH functionalised fluorescent Quantum Dots for staining Hydra vulgaris” C. Tortiglione, A. Quarta, A. Tino, L. Manna, R. Cingolani and T. Pellegrino (Bioconjugate Chemistry, 18, 829-835, 2007) *

"Gel Electrophoresis of Gold-DNA Nano-Conjugates" by W. J. Parak, T. Pellegrino, Ralph A. Sperling, and A. P. Alivisatos, (Journal of Biomedicine and Biotechnology 2008, Volume 2007, Article ID 26796, 9 pages, doi:10.1155/2007/26796)

2006

“Synthesis, properties and perspectives of hybrid nanocrystal structures” Pantaleo Davide Cozzoli, Teresa Pellegrino and Liberato Manna (Chemical Society Review, 35: 1195-1208 September 11, 2006)

“Heterodimers based on CoPt3-Au nanocrystals with tunable domain size” Teresa Pellegrino, Angela Fiore, Elvio Carlino, Cinzia Giannini, P. Davide Cozzoli, Giuseppe Ciccarella, Marc Respaud, Luca Palmirotta, Roberto Cingolani, and Liberato Manna (Journal Of The American Chemical Society 128 (20): 6690-6698 MAY 24 2006) *

“Electrophoretic Separation of Nanoparticles with a Discrete Number of Functional Groups” Ralph A. Sperling, Teresa Pellegrino, Jimmy K. Li, Walter H. Chang and Wolfgang J. Parak (Advanced Functional Materials 16 (7): 943-948 MAY 2 2006)

“Fluorescence resonance energy transfer induced by conjugation of metalloproteins to nanoparticles” Pompa PP, Chiuri R, Manna L, Pellegrino T, del Mercato LL, Parak WJ, Calabi F, Cingolani R, Rinaldi R (Chemical Physics Letters 417 (4-6): 351-357 JAN 10 2006)

2005

“On the Development of Colloidal Nanoparticles towards Multifunctional Structures and their Possible Use for Biological Applications” Teresa Pellegrino, Stefan Kudera, Tim Liedl, Almudena Munoz Javier, Liberato Manna, and Wolfgang J. Parak (Small 1(1): 8-63, 2005).

“Labeling of Cells with Quantum Dots” Wolfgang J. Parak, Teresa Pellegrino, Christian Plank (Nanotechnology 16: r9-r25, 2005 invited paper) topical review.

“Quantum Dot-Based Cell Motility Assay In Comparison to the Boyden Chamber Invasion Assay” Weiwei Gu, Teresa Pellegrino, Wolfgang J. Parak, Rosanne Boudreau, Mark A. Le Gros, Daniele Gerion, A. Paul Alivisatos, and Carolyn A. Larabell (Science’s STKE, 290/PI5:1-6, 2005 on-line publication)

“Biological Applications of Fluorescent Quantum Dots” Tim Liedl, Teresa Pellegrino and Wolfgang J. Parak (New Drugs: 14-16, 2005)

“Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles” Christian Kirchner Tim Liedl, Stefan Kudera, Teresa Pellegrino, Almudena Munoz Javier, Hermann E. Gaub, Sonja Stoelzle, N. Fertig, Wolfgang J. Parak (Nano Letters 5 (2): 331-338, 2005).

2004

“Hydrophobic nanocrystals coated with an amphiphilic polymer shell: a general route to water soluble nanocrystals”, Teresa Pellegrino, Liberato Manna, Stefan Kudera, Dmitry Koktysh, Andrey L. Rogach, Giovanni Natile and Wolfgang J. Parak (Nano Letters 4 (4): 703-707, 2004).

‘Selective Transition Metal Extraction by Reverse Micelles’, Maurizio Caselli, Annarosa Mangone, Teresa Pellegrino and Angela Traini, (Annali di Chimica 95 (1-2): 33-43, 2004).

“Surface modification and bioconjugation of colloidal nanocrystals to form building blocks with molecular recognition” R. A. Sperling, T. Pellegrino, S. Kudera, A Munoz Javier, L. Manna and W. J. Parak. Proceedings for the 2004 4th IEEE Conference on Nanotechnology (223-224)

2003

‘Quantum Dot Based Cell Motility Assay’, Teresa Pellegrino, Wolfgang J. Parak, Rosanne Boudreau, Mark A. Le Gross, A. Paul Alivisatos and Carolyn A. Larabell, (Differentiation 71 (9-10): 542-548, 2003).

Biological Applications of Colloidal Nanocrystals’ W. J. Parak, D. Gerion, T. Pellegrino, D. Zanchet, C. M. Micheel, S. Williams, R. Boudreau, M. Le Gros, C. Larabell & P. Alivisatos, (Nanotechnology 14 (7): r15-r27, 2003).

‘Conformation of oligonucleotides attached to gold nanocrystals probed by gel-electrophoresis’, W. J. Parak, T. Pellegrino, C. M. Micheel, D. Gerion, S. Williams & P. Alivisatos, (Nano Letters 3(1): 33-36, 2003).

2002

‘Conjugation of DNA to silanized colloidal semiconductor nanocrystallinene quantum dots’, W. J. Parak, D. Gerion, D. Zanchet, A. Woerz, T. Pellegrino, C. M. Micheel, , S. Williams, M. Seitz, R. Bruehel, Z. Bryant, C. Bustamante, C. Bertozzi & P. Alivisatos, (Chemistry of Materials 14: 2113-2119, 2002).

Projects

3.4 Personal Grants

2001:                     University of Caserta, 6- months fellowship to be visiting research in USA (California)

2003-2004:          12 months Marie Curie Fellowship at the Center for Nanoscience, Munich (Germany)

 

3.5 Major Research Grants Secured

(ongoing)

2016-2019           Starting European Research Council (ERC)-Individual Grant, “Colloidal Inorganic Nanostructures for Radiotherapy and Chemotherapy”,( ICARO, contract number 678109)

2016-2020           Horizon 2020 under MSCA RISE call, One of the Scientific PI of IIT, ”Colloidal Nanomaterials for Smart Applications” (COMPASS – 691185, coordinator Roman Khrane)

2014-2016           Principal Investigator for the AIRC (Italian Association of Cancer Research), Individual Grant, Project: Stimuli-Responsive Nanoparticles for eradicating different subsets of cancer cells within tumors, (Acronym NanoCures)

2014-2017           Fondazione Cariplo project, Scientific PI for IIT partner for the project “Disease recurrence in epithelial ovarian cancer: deciphering miRNA-driven regulatory networks related to drug sensitivity/cellular plasticity and exploring nanomaterial-based targeted delivery of identified key molecules for therapeutic purposes”

2012-2016:          European Marie Curie Training Networks (ITN) – Scientific PI for IIT partner (MAG(NET)ICFUN- Functionalized Magnetic Nanoparticles and their Application in Chemistry and Biomedicine, contract  number 290248)

(past grants)

2011-2013:          Scientific PI for CNR partner of an AIRC project entitled “miRNA profile associated to clinical response in ovary cancer: biological/clinical implications” - cod. 10302., P.I.: Silvana Canevari, Istituto Nazionale dei Tumori, Milan (Italy)

2009-2013:          European project FP7 SMALL, Project Coordinator (Magnetic Nanocontainers for Combined Hyperthermia and Controlled Drug Release MAGNIFYCO, contract n. 228622, www.magnifyco.eu, magnetic nanocontainers for combined hyperthermia and controlled drug release)

2005-2006:          PI as external partner for CNR of an Italian National Research Program on “New types of contrast agents for magnetic resonance imaging and tissue targeting: brain damage in animal model” funded by the Italian Ministry of University and Research.

 

 

Selected Publications

Since my first publication in 2002, so far I have published in total 91 papers in international journals (5 invited reviews, 5 as a first author and 39 out of 91 as corresponding author).

See also http://scholar.google.it/citations?user=ssxCVUAAAAAJ&hl=it  or my personal webpage at iit website for the full list of talks. I was invited to write review articles for several journals (among them Chemical Society Reviews, IEEE Transaction on Nanobioscience, Pharmacological Research, Nanoscale) and 7 book chapters. I also have 5 patents

Awards

Honours, Awards, research highlights

 

2016                      Awarded “European award of the European Group of Chemistry and Biology 2016”, the GEQB award will be received in March 2016, http://quimicabiologica.es/blog/files/category-awards.html

2014                National habilitation as Full Professor for the area of "Fundamental of Chemical Science and Inorganic System for the period starting on 23/12/2013 and ending on 23/12/2017 (Docente di prima fascia)

2013                      Awarded “Apulia Women Talent 2012” assigned by Lions International Club for the work carried out on the topic “Magnetic Nanocontainers for Combined Hyperthermia and Controlled Drug Release”.

2012                      Highlighted by Chemical Communications as among the top emerging investigators in Chemical Sciences. My research article was published in the first Chem Comm issue of 2012, along with biography profile:

http://pubs.rsc.org/en/content/articlelanding/2012/cc/c2cc17223b

2011                       My review “From iron oxide nanoparticles towards advanced iron-based inorganic materials designed for biomedical applications”, August 2010) was among the most downloaded articles in Pharmacological Research. In 2011:

http://www.journals.elsevier.com/pharmacological-research/most-cited-articles/

2009                       My manuscript, Pellegrino t et al., Nano Lett. 2004, 4 (4), 703, was selected as an “Emerging Research Front Paper in the field of Materials Science” issue by ScienceWatch (Thomson Reuters)

2009                       Internationational Award “Primo Levi” from the Italian Chemical Society (for investigators younger than 35), for the work: “Multifuctional Nanostructures Based on Inorganic Nanoparticles and Oligothiophenes and their Exploitation for Cellular Studies” A. Quarta, R. Di Corato, L. Manna, S. Argentiere, R Cingolani, G. Barbarella and T. Pellegrino, (Journal of the American Chemical Society, 2008,130, 10545-10555). The same work was also selected for the special JACS issue: ”Chemistry at Nano-Bio Interface” published in July 2009.

 

Covers of journals articles

2013 Front cover: Silva K. A. et al ( 2013, Nanoscale, 2013 5 (23), 11374-11384)

2014 Back cover: Guardia P. et al (Journal of Materials Chemistry B,2013,  2, 4426-4434)

2015 Back cover: Quarta A. et al (Nanoscale, 2013, 7, 2336–2351)

 

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I numeri di IIT

L’Istituto Italiano di Tecnologia (IIT) è una fondazione di diritto privato - cfr. determinazione Corte dei Conti 23/2015 “IIT è una fondazione da inquadrare fra gli organismi di diritto pubblico con la scelta di un modello di organizzazione di diritto privato per rispondere all’esigenza di assicurare procedure più snelle nella selezione non solo nell’ambito nazionale dei collaboratori, scienziati e ricercatori ”.

IIT è sotto la vigilanza del Ministero dell'Istruzione, dell'Università e della Ricerca e del Ministero dell'Economia e delle Finanze ed è stato istituito con la Legge 326/2003. La Fondazione ha l'obiettivo di promuovere l'eccellenza nella ricerca di base e in quella applicata e di favorire lo sviluppo del sistema economico nazionale. La costruzione dei laboratori iniziata nel 2006 si è conclusa nel 2009.

Lo staff complessivo di IIT conta circa 1440 persone. L’area scientifica è rappresentata da circa l’85% del personale. Il 45% dei ricercatori proviene dall’estero: di questi, il 29% è costituito da stranieri provenienti da oltre 50 Paesi e il 16% da italiani rientrati. Oggi il personale scientifico è composto da circa 60 principal investigators, circa 110 ricercatori e tecnologi di staff, circa 350 post doc, circa 500 studenti di dottorato e borsisti, circa 130 tecnici. Oltre 330 posti su 1400 creati su fondi esterni. Età media 34 anni. 41% donne / 59 % uomini.

Nel 2015 IIT ha ricevuto finanziamenti pubblici per circa 96 milioni di euro (80% del budget), conseguendo fondi esterni per 22 milioni di euro (20% budget) provenienti da 18 progetti europei17 finanziamenti da istituzioni nazionali e internazionali, circa 60 progetti industriali

La produzione di IIT ad oggi vanta circa 6990 pubblicazioni, oltre 130 finanziamenti Europei e 11 ERC, più di 350 domande di brevetto attive, oltre 12 start up costituite e altrettante in fase di lancio. Dal 2009 l’attività scientifica è stata ulteriormente rafforzata con la creazione di dieci centri di ricerca nel territorio nazionale (a Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) e internazionale (MIT ed Harvard negli USA) che, unitamente al Laboratorio Centrale di Genova, sviluppano i programmi di ricerca del piano scientifico 2015-2017.

IIT: the numbers

Istituto Italiano di Tecnologia (IIT) is a public research institute that adopts the organizational model of a private law foundation. IIT is overseen by Ministero dell'Istruzione, dell'Università e della Ricerca and Ministero dell'Economia e delle Finanze (the Italian Ministries of Education, Economy and Finance).  The Institute was set up according to Italian law 326/2003 with the objective of promoting excellence in basic and applied research andfostering Italy’s economic development. Construction of the Laboratories started in 2006 and finished in 2009.

IIT has an overall staff of about 1,440 people. The scientific staff covers about 85% of the total. Out of 45% of researchers coming from abroad 29% are foreigners coming from more than 50 countries and 16% are returned Italians. The scientific staff currently consists of approximately 60 Principal Investigators110 researchers and technologists350 post-docs and 500 PhD students and grant holders and 130 technicians. External funding has allowed the creation of more than 330 positions . The average age is 34 and the gender balance proportion  is 41% female against 59% male.

In 2015 IIT received 96 million euros in public funding (accounting for 80% of its budget) and obtained 22 million euros in external funding (accounting for 20% of its budget). External funding comes from 18 European Projects, other 17 national and international competitive projects and approximately 60 industrial projects.

So far IIT accounts for: about 6990 publications, more than 130 European grants and 11 ERC grants, more than 350 patents or patent applications12 up start-ups and as many  which are about to be launched. The Institute’s scientific activity has been further strengthened since 2009 with the establishment of 11 research nodes throughout Italy (Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) and abroad (MIT and Harvard University, USA), which, along with the Genoa-based Central Lab, implement the research programs included in the 2015-2017 Strategic Plan.