Paolo Bianchini studied Physics at the Department of Physics, University of Genoa, Genoa, Italy, and received his Master degree in 2004. In 2008, he received his Ph.D degree in Materials Science at the Department of Physics, University of Genoa, Genoa, Italy. Up to the end of 2009, he worked as a post-doctoral fellow at the same institute. In 2010 he moved to Istituto Italiano di Tecnologia Genoa, Italy, where in January 2012 he obtained a researcher position, and in January 2016 he became research manager of the Nikon Imaging Center at IIT.
His primary research activity aims at the biophysical study of biological molecules and macromolecules both in situ and in vitro utilizing almost not perturbative instrumentation and nanostructured model systems. So far, his research interests deal with the theoretical design, development, and validation of novel optical and biophysical instrumentations, which allow imaging and probing the matter from thin to thick and highly scattering biological specimens, at unprecedented temporal and spatial resolution, taking advantage of novel label-free contrast methods too. In particular, he developed original setups for multiphoton excitation nanoscopy (single wavelength two-photon excitation stimulated emission depletion, SW 2PE-STED) and label-free related high or super-resolution microscopy methods (polarization second harmonic generation, PSHG, image weighted subtraction, IWS, label-free pump-probe nanoscopy). Other interests are the study on biological molecules to address cell functioning using conventional, confocal microscopy, FLIM (Fluorescence Lifetime Imaging Microscopy), single molecule imaging, spectral microscopy, nanostructured model systems, bioimaging. He worked also on a nanotechnological approach for the realization of Nano-bio-robot, hybrid nanostructured devices made by living cells and polyelectrolyte layers.
PB is an active member of international scientific societies and has been selected as a reviewer of different international scientific journals: Biophysical Journal, Journal of Biomedical Optics, Photochemical & Photobiological Sciences. He is associate editor of Microscopy Research and Technique journal.
In 2013 he received the prize Innovators Under 35 Italia, by MIT Technology Review
In 2004 he received the GIC (Citometry Italian Society) Massimo Grattarola Award for the master degree thesis.