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Alessandro Bosca Write a Message

Junior Technician

Research Line

Plasmon Nanotechnologies


Via Valtrebbia 43 / 5
+39 010 71781 431


Alessandro Bosca graduated with full marks in Physics at the University of Genoa in 2006, studying viscoelasticity and adhesion of polymers on nanostructured surfaces on the micrometric scale by means of Atomic Force Microscopy (AFM). His research had taken place within a national PRIN 2004-2006 centered on “Nanotribology” and benefited of the collaboration of the S3 National Research Center of CNR-INFM in Modena. In his work colloidal AFM probes has been created and an experimental setup and methodology has been developed and implemented by commercial hardware and custom made software. Silicon substrates have been consciously nanostructured, using a modified algorithm for fractal surfaces generation, with a Focused Ion Beam (FIB). The precision of the milling process has been characterized and optimized.

Currently, he has a Ph.D student position at Italian Institute of Technology (IIT) on the developing and characterization of a new nanostructured device for measuring the electrophysiological activity of biological neuronal networks. In order to perform his tasks he is now concerning with topics just like alternative micro and nano-structuring techniques, biomaterials, biosensors, microfluidics and cell adhesion while deepening his knowledge in laboratory related subjects like cell cultures, electrophysiological techniques, electronics and object oriented programming.

Alessandro Bosca has a good experimental and theoretical background in the use of AFM, especially in force spectroscopy, and experience in the physics and use of polymers and Focused Ion Beam. Thanks to his academic preparation he has fundamental knowledge about the physics of mesoscopic systems and biophysics; also he can use analytical techniques like optical, confocal, two-photon and SEM microscopy.



Development of a Nanostructured Device for Measuring the Electrophysiological Activity of Biological Neural Networks





Valbusa Ugo



The final aim of this project is the development of a planar patch clamp device suited to measure simultaneously the ionic currents flowing in cultured neurons associated in a network. This will permit to study the molecular mechanism underlying information coding and propagation in biological neural systems and therefore investigate the physiological behavior of neuronal networks in their functioning and developing.

Selected Publications

R.Buzio , A.Bosca , S.Krol , D.Marchetto , S.Valeri and U.Valbusa
Deformation and Adhesion of Elastomer Polydimethylsiloxane Colloidal AFM Probes.
Langmuir Vol. 23, No. 18 p.9293-9302


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I numeri di IIT

L’Istituto Italiano di Tecnologia (IIT) è una fondazione di diritto privato - cfr. determinazione Corte dei Conti 23/2015 “IIT è una fondazione da inquadrare fra gli organismi di diritto pubblico con la scelta di un modello di organizzazione di diritto privato per rispondere all’esigenza di assicurare procedure più snelle nella selezione non solo nell’ambito nazionale dei collaboratori, scienziati e ricercatori ”.

IIT è sotto la vigilanza del Ministero dell'Istruzione, dell'Università e della Ricerca e del Ministero dell'Economia e delle Finanze ed è stato istituito con la Legge 326/2003. La Fondazione ha l'obiettivo di promuovere l'eccellenza nella ricerca di base e in quella applicata e di favorire lo sviluppo del sistema economico nazionale. La costruzione dei laboratori iniziata nel 2006 si è conclusa nel 2009.

Lo staff complessivo di IIT conta circa 1440 persone. L’area scientifica è rappresentata da circa l’85% del personale. Il 45% dei ricercatori proviene dall’estero: di questi, il 29% è costituito da stranieri provenienti da oltre 50 Paesi e il 16% da italiani rientrati. Oggi il personale scientifico è composto da circa 60 principal investigators, circa 110 ricercatori e tecnologi di staff, circa 350 post doc, circa 500 studenti di dottorato e borsisti, circa 130 tecnici. Oltre 330 posti su 1400 creati su fondi esterni. Età media 34 anni. 41% donne / 59 % uomini.

Nel 2015 IIT ha ricevuto finanziamenti pubblici per circa 96 milioni di euro (80% del budget), conseguendo fondi esterni per 22 milioni di euro (20% budget) provenienti da 18 progetti europei17 finanziamenti da istituzioni nazionali e internazionali, circa 60 progetti industriali

La produzione di IIT ad oggi vanta circa 6990 pubblicazioni, oltre 130 finanziamenti Europei e 11 ERC, più di 350 domande di brevetto attive, oltre 12 start up costituite e altrettante in fase di lancio. Dal 2009 l’attività scientifica è stata ulteriormente rafforzata con la creazione di dieci centri di ricerca nel territorio nazionale (a Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) e internazionale (MIT ed Harvard negli USA) che, unitamente al Laboratorio Centrale di Genova, sviluppano i programmi di ricerca del piano scientifico 2015-2017.

IIT: the numbers

Istituto Italiano di Tecnologia (IIT) is a public research institute that adopts the organizational model of a private law foundation. IIT is overseen by Ministero dell'Istruzione, dell'Università e della Ricerca and Ministero dell'Economia e delle Finanze (the Italian Ministries of Education, Economy and Finance).  The Institute was set up according to Italian law 326/2003 with the objective of promoting excellence in basic and applied research andfostering Italy’s economic development. Construction of the Laboratories started in 2006 and finished in 2009.

IIT has an overall staff of about 1,440 people. The scientific staff covers about 85% of the total. Out of 45% of researchers coming from abroad 29% are foreigners coming from more than 50 countries and 16% are returned Italians. The scientific staff currently consists of approximately 60 Principal Investigators110 researchers and technologists350 post-docs and 500 PhD students and grant holders and 130 technicians. External funding has allowed the creation of more than 330 positions . The average age is 34 and the gender balance proportion  is 41% female against 59% male.

In 2015 IIT received 96 million euros in public funding (accounting for 80% of its budget) and obtained 22 million euros in external funding (accounting for 20% of its budget). External funding comes from 18 European Projects, other 17 national and international competitive projects and approximately 60 industrial projects.

So far IIT accounts for: about 6990 publications, more than 130 European grants and 11 ERC grants, more than 350 patents or patent applications12 up start-ups and as many  which are about to be launched. The Institute’s scientific activity has been further strengthened since 2009 with the establishment of 11 research nodes throughout Italy (Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) and abroad (MIT and Harvard University, USA), which, along with the Genoa-based Central Lab, implement the research programs included in the 2015-2017 Strategic Plan.