The Center for Cultural Heritage Technology (CCHT) aims at researching and promoting new technologies for the analysis and preservation of Cultural Heritage, both tangible and intangible, expanding and improving current approaches.

The Center for Human Technologies (CHT) approach is based on a multidisciplinary vision in collaboration with research hospitals and clinical institutions, in order to conceive new technologies or improve the existing ones.

The Center for Life Nano- & Neuro-Science (CLNS) revolves around topics of biomedical interest where technological innovation is key to reach the goals, such as neurodegenerative disorders and brain tumors.

The Center for Materials Interfaces (CMI) is dedicated to the investigation, development, characterization, and exploitation of materials at the nanoscale, with a special focus on interface effects.

The Center for Neuroscience and Cognitive Systems (CNCS) is focused on neuroscience in human subjects and animal models, including psychophysical techniques, functional imaging, and computational approaches.

The Center for Nanotechnology Innovation (CNI) is an interdisciplinary R&D center dedicated to the investigation and exploitation of phenomena at the nanoscale.

The Center for Advanced Biomaterials for Healthcare (CABHC) develops materials and technologies to engineer bio-logically inspired platforms and systems for applications in the biomedical sector.

The Center for Synaptic Neuroscience and Technology (NSYN) applies multidisciplinary approaches to study brain function and diseases and seeks to develop novel technologies for neuroscience applications.

The Center for Biomolecular Nanotechnologies (CBN) is a large-scale facility for bio-molecular and organic materials and nanoscale biomolecular interactions.

The Center for Convergent Technologies (CCT) is the largest research infrastructure of the whole IIT network and it is where the Foundation started its activity in 2006.

The Center for Genomic Science (CGS) applies modern genomic technologies for understanding the complex biological processes and diseases, with particular emphasis on Cancer.

The Center for Nano Science and Technology (CNST) aims at "innovation", therefore the goal of the CNST scientific team is to transfer new basic knowledge into new applications.

The Center for Robotics and Intelligent Systems (CRIS) hosts IIT roboticists in a collaborative environment. Here, indoor and outdoor spaces simulate the operation environments where our robots have to operate.

The Center for Sustainable Future Technologies (CSFT) has embraced sustainability in its mission statement and is engaged in the global scientific and technological endeavours to address sustainability challenges.

The Center for Translational Neurophysiology of Speech and Communication (CTNSC) investigates the brain processes of the communicative behaviors related to communicative intentions.