I hold a Master's Degree in Chemistry and a Ph.D. in Biochemistry. During my Ph.D. I synthesized and characterized by liquid chromatography and mass spectrometry several molecules to be tested in vitro as correctors and/or potentiators of CFTR (Cystic Fibrosis transmembrane conductance regulator). After my doctorate, I continued to deepen my knowledge about the synthesis and characterization of biomolecules at the Centre of Excellence for Biomedical Research (CEBR) at the University of Genova. I have been working in the Analytical Chemistry Lab of Istituto Italiano di Tecnologia since October 2019, where I have been acquiring new skills in the field of bioanalytical chemistry and mass spectrometry, in particular in proteomics, lipidomics and metabolomics. During this period I published 3 papers as first author.
Research center
CHT@Erzelli
About
All Publications
2023
Liessi N., Tomati V., Capurro V., Loberto N., Garcia-Aloy M., Franceschi P., Aureli M., Pedemonte N., Armirotti A.
The combination elexacaftor/tezacaftor/ivacaftor (ETI) modulates the de novo synthethic pathway of ceramides in a genotype-independent manner
Journal of Cystic Fibrosis
2022
Braccia C., Christopher J.A., Crook O.M., Breckels L.M., Queiroz R.M.L., Liessi N., Tomati V., Capurro V., Bandiera T., Baldassari S., Pedemonte N., Lilley K.S., Armirotti A.
CFTR Rescue by Lumacaftor (VX-809) Induces an Extensive Reorganization of Mitochondria in the Cystic Fibrosis Bronchial Epithelium
Cells, vol. 11, (no. 12)
2022
Contardi M., Ayyoub A.M.M., Summa M., Kossyvaki D., Fadda M., Liessi N., Armirotti A., Fragouli D., Bertorelli R., Athanassiou A.
Self-Adhesive and Antioxidant Poly(vinylpyrrolidone)/Alginate-Based Bilayer Films Loaded with Malva sylvestris Extracts as Potential Skin Dressings
ACS Applied Bio Materials, vol. 5, (no. 6), pp. 2880-2893
2022
Lunghi G., Carsana E.V., Loberto N., Cioccarelli L., Prioni S., Mauri L., Bassi R., Duga S., Straniero L., Asselta R., Solda G., Di Fonzo A., Frattini E., Magni M., Liessi N., Armirotti A., Ferrari E., Samarani M., Aureli M.
β-Glucocerebrosidase Deficiency Activates an Aberrant Lysosome-Plasma Membrane Axis Responsible for the Onset of Neurodegeneration
Cells, vol. 11, (no. 15)
2021
Liessi N., Maragliano L., Castagnola V., Bramini M., Benfenati F., Armirotti A.
Isobaric Labeling Proteomics Allows a High-Throughput Investigation of Protein Corona Orientation
Analytical Chemistry, vol. 93, (no. 2), pp. 784-791
Colleagues of Computational and Chemical Biology