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Luca Pandolfini

Researcher
Researcher
Non-coding RNAs and RNA-based therapeutics
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About
Education

Title: PhD in Neurobiology
Institute: Scuola Normale Superiore di Pisa
Location: Pisa
Country: Italy
From: 2011 To: 2015

Title: Master’s degree in Molecular and Cell Biology
Institute: Scuola Normale Superiore di Pisa
Location: Pisa
Country: Italy
From: 2009 To: 2011

Experience External

Title: Research Associate
Institute: Gurdon Institute - University of Cambridge
Location: Cambridge
Country: United Kingdom
From: 2015 To: 2019

Top Publications
2022
Dunville K., Tonelli F., Novelli E., Codino A., Massa V., Frontino A.M., Galfrè S., Biondi F., Gustincich S., Caleo M., Pandolfini L., Alia C., Cremisi F.
Laminin511 and WNT signalling sustain prolonged expansion of hiPSC-derived hippocampal progenitors.
Development (Cambridge)
2022
Valentini P., Pierattini B., Zacco E., Mangoni D., Espinoza S., Webster N.A., Andrews B., Carninci P., Tartaglia G.G., Pandolfini L., Gustincich S.
Towards SINEUP-based therapeutics: Design of an in vitro synthesized SINEUP RNA
Molecular Therapy - Nucleic Acids, vol. 27, pp. 1092-1102
Article Journal
2021
Leger A., Amaral P.P., Pandolfini L., Capitanchik C., Capraro F., Miano V., Migliori V., Toolan-Kerr P., Sideri T., Enright A.J., Tzelepis K., van Werven F.J., Luscombe N.M., Barbieri I., Ule J., Fitzgerald T., Birney E., Leonardi T., Kouzarides T.
RNA modifications detection by comparative Nanopore direct RNA sequencing
Nature Communications, vol. 12, (no. 1)
2019
Pandolfini L., Barbieri I., Bannister A.J., Hendrick A., Andrews B., Webster N., Murat P., Mach P., Brandi R., Robson S.C., Migliori V., Alendar A., d'Onofrio M., Balasubramanian S., Kouzarides T.
METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation
Molecular Cell, vol. 74, (no. 6), pp. 1278-1290.e9
2017
Barbieri I., Tzelepis K., Pandolfini L., Shi J., Millan-Zambrano G., Robson S.C., Aspris D., Migliori V., Bannister A.J., Han N., De Braekeleer E., Ponstingl H., Hendrick A., Vakoc C.R., Vassiliou G.S., Kouzarides T.
Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
Nature, vol. 552, (no. 7683), pp. 126-131