Publications
2026
Rifai O.M., Waldron F.M., O'Shaughnessy J., Read F.L., Gilodi M., Pastore A., Shneider N.A., Tartaglia G.G., Zacco E., Spence H., Gregory J.M.
Amygdala TDP-43 pathology is associated with behavioural dysfunction and ferritin accumulation in amyotrophic lateral sclerosis
Brain Communications, vol. 8, (no. 2)
2026
Milordini G., Zacco E., Masi M., Armaos A., Di Palma F., Oneto M., Gilodi M., Rupert J., Broglia L., Varignani G., Scotto M., Marotta R., Girotto S., Cavalli A., Tartaglia G.G.
Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality
Nature Communications, vol. 17, (no. 1)
2026
Broglia L., Canale C., Vandelli A., Tartaglia G.G., Delli Ponti R.
Decoding the Structural Complexity of Viral RNAs with SHAPE to Guide Antiviral Therapeutics
Viruses, vol. 18, (no. 5)
2026
Ferolito B.R., Dashti H., Giambartolomei C., Peloso G.M., Golden D.J., Gravel-Pucillo K., Rasooly D., Horimoto A.R.V.R., Matty R., Gaziano L., Liu Y., Smit I.A., Zdrazil B., Tsepilov Y., Costa L., Kosik N., Huffman J.E., Tartaglia G.G., Bini G., Proietti G., Ioannidis H., Karim M.A., Hunter F., Hemani G., Butterworth A.S., Di Angelantonio E., Langenberg C., Ghoussaini M., Leach A.R., Liao K.P., Damrauer S., Selva L.E., Whitbourne S., Tsao P.S., Moser J., Gaunt T., Cai T., Whittaker J.C., Casas J.P., Muralidhar S., Gaziano J.M., Cho K., Pereira A.C.
Leveraging large-scale biobanks for therapeutic target discovery
Human Genetics and Genomics Advances, vol. 7, (no. 1)
2026
Fiorentino J., Monti M., Broglia L., Tartaglia G.G.
Physicochemical principles of RNA-mediated crowding
Current Opinion in Structural Biology, vol. 100
2026
Broglia L., Dasti A., Antonelli M.C., Aoun G., D'Agostino S., Vandelli A., Armaos A., DelliPonti R., Wolf S., Klostermann M., ArnalSegura M., Tian T.V., Mariani D., Colantoni A., Paronetto M.P., Gustincich S., Zarnack K., Bechara E., Tartaglia G.G.
SAM68 is a multifunctional post-transcriptional regulator of cardiomyocyte differentiation
Nucleic Acids Research, vol. 54, (no. 10)
2026
Fiorentino J., Armaos A., Montrone C., Colantoni A., Tartaglia G.G.
scRAPID-web: a web server for predicting protein–RNA interactions from single-cell transcriptomics
BMC Genomics, vol. 27, (no. 1)
2026
Setti A., Bini G., Flaminia P., Maiorca V., Proietti G., Vrachnos D.M., D'Angelo A., Armaos A., Martone J., Monti M., Ruocco G., Rodolà E., Bozzoni I., Colantoni A., Tartaglia G.G.
The role of low-complexity repeats in RNA-RNA interactions and a deep learning framework for duplex prediction
Nature Communications
2025
Vedeler A., Tartaglia G.G., Pastore A.
Annexin, a Protein for All Seasons: From Calcium Dependent Membrane Metabolism to RNA Recognition
BioEssays
2025
Foord C., Prjibelski A.D., Hu W., Michielsen L., Vandelli A., Narykov O., Evans B., Hsu J., Belchikov N., Jarroux J., He Y., Ross M.E., Hajirasouliha I., Tartaglia G.G., Korkin D., Tomescu A.I., Tilgner H.U.
A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types
Nature Communications, vol. 16, (no. 1)
2025
Monti M., Fiorentino J., Miltiadis-Vrachnos D., Bini G., Cotrufo T., SanchezdeGroot N., Armaos A., Tartaglia G.
catGRANULE 2.0: accurate predictions of liquid-liquid phase separating proteins at single amino acid resolution
Genome Biology, vol. 26, (no. 1)
2025
Milordini G., Zacco E., Masi M., Armaos A., Di Palma F., Oneto M., Gilodi M., Rupert J., Broglia L., Varignani G., Scotto M., Marotta R., Girotto S., Cavalli A., Tartaglia G.G.
Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality
Nature Communications, vol. 17, (no. 1)
2025
Milordini G., Zacco E., Armaos A., Di Palma F., Masi M., Gilodi M., Rupert J., Broglia L., Varignani G., Oneto M., Scotto M., Marotta R., Girotto S., Cavalli A., Tartaglia G.G.
Computationally-designed aptamers targeting RAD51-BRCA2 interaction inhibit RAD51 nuclear recruitment
bioRxiv
2025
Bini G., Tartaglia G.G.
Deep Learning Approaches to Predict RNA-RNA interactions
PhD Thesis
Book
2025
Alriquet M., Arsie R., Calloni G., Tartaglia G.G., Vabulas R.M.
Deficiency of N1-Adenine Methyltransferase Aggravates RNA and Protein Aggregation
Cells, vol. 14, (no. 17)
2025
Luige J., Conrad T., Armaos A., Louloupi A., Vincent A., Meierhofer D., Gajhede M., Tartaglia G.G., Orom U.A.V.
Design and characterization of G-quadruplex RNA aptamers reveal RNA-binding by KDM5 lysine demethylases
Computational and Structural Biotechnology Journal, vol. 27, pp. 2719-2729
2025
Intze A., Temperini M.E., Rupert J., Polito R., Veber A., Puskar L., Schade U., Ortolani M., Zacco E., Tartaglia G.G., Giliberti V.
Effect of RNA on the supramolecular architecture of α-synuclein fibrils
Biophysical Journal
2025
Mangoni D., Mazzetti A., Ansaloni F., Simi A., Tartaglia G.G., Pandolfini L., Gustincich S., Sanges R.
From the genome’s perspective: bearing somatic retrotransposition to leverage the regulatory potential of L1 RNAs
BioEssays, vol. 47, (no. 2), pp. e2400125