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Pablo Guardia Giros

Affiliated Researcher
TecnioSpring MarieCurie Researcher

Research Line

Nanomaterials for Biomedical Applications

Center

IIT Central Research Labs Genova

Contacts

Via Morego, 30 16163 Genova, Italy.
Contact Me

About

After getting my degrees in Physics (Universitat de Barcelona, 2004) and Material Science and Engineering (Universtiat Politecnica de Catalunya, 2006) I started my research career with my master thesis about Synthesis of Magnetic Nanoparticles (Master in Nanoscience and Nanotechnology, Universitat de Barcelona, 2007). As a researcher my work has been initially focused in the colloidal synthesis of nanoparticles for applications in nanomedicine (PhD at the University of Barcelona, Universitat de Barcelona, 2006-2009). I continued during my postdoc training at IIT (2010-2013) developing nanoparticles for biomedicine (FP7-MAGNYFICO and NANO-ARCH ERC) and extending my skills in catalysis (Istituto Italiano di Tecnologia 2012-2014). April 2014 I joined the Catalonian Institute for Energy Research (IREC) where my research moved to the development of novel hierarchical superstructures (FP7-UNION) and continued at the Center for Chemical Technology (CTQC) and Dublin City University (DCU) under the TECSPR14-1-0053 project. As an independent researcher, I carried out the activities of this project in between IREC and the University Pompeu Fabra. November 2016 I joined the Catalan Institute of Nanoscience and Nanotechnology (ICN2) where I keep exploiting nanoparticles as building blocks for novel graphene-based nanocomposites for micromotors. Currently my activities are focused in the development of novel hierarchical suprastructures (clusters or aerogels) out of inorganic and graphene nanosized building blocks. Currently my research is carried out at the Catalonia Institute for Energy Research (Barcelona) as a TecnioSpring-MarieCurie research fellow and at the Italian Institute of Technology (Genova) as an associate researcher.

Interests

Magnetic nanoparticles nanomedicine nanobitechnology hyperthermia nanoheterostructures gels aerogels nanoestructured composites

Projects

1) Smart nanoclusters for photo-magnetic hyperthermia TECSPR16-1-0082
PI: Pablo Guardia; Andreu Cabot                      Funding entity or bodies: ACCIÓ
Type of participation: coordinator
Name of the programme: TECNIOSPRING MarieCurie Action
Total amount: 115.457,58 €                               Start-End date: 01/09/2017 - 31/08/2019

2) Magneto-hipotermia: Es posible enfriar remotamente celulas o entidades subcelulares? SAF2015-73052-EXP
PI: Pilar Rivera Gil                      Funding entity or bodies: MINISTERIO DE EDUCACION Y CIENCIA
Type of participation: coordinator
Name of the programme: EXPLORA
Total amount: 35.000 €                                       Start-End date: 01/06/2016 - 31/05/2018 Duration: 2 years

3) Rational design of nanoclusters for biomedical applications
PI: Pablo Guardia; Pilar Rivera Gil                      Funding entity or bodies: ACCIÓ
Type of participation: coordinator
Name of the programme: TECNIOSPRING MarieCurie Action
Total amount: 96.378,26 €                                   Start-End date: 01/11/2014 - 31/10/2016 Duration: 2 years

4) Ultra-versatile Nanoparticle Integration into Organized Nanoclusters (Union 310250)
PI: Dermot Brougham; Andreu Cabot                  Funding entity or bodies: European Commission CORDIS
Type of participation: Team member
Name of the programme: SEVENTH FRAMEWORK PROGRAMME (FP7)
Total amount: 3.798.053 €                                   Start-End date: 01/02/2013 - 31/01/2016 Duration: 3 years

5) ERC Starting Grant NANO-ARCH (NANO-ARCH, contract n. 240111).
PI: Liberato Manna                                               Funding entity or bodies: FP7 ERC Starting Grant
Type of participation: Team member
Name of the programme: EUROPEAN RESEARCH COUNCIL (ERC)
Code according to the funding entity: contract n. 240111
Total amount: 1.300.000 €                                    Start-End date: 01/11/2009 - 31/10/2013 Duration: 9 months

6) Name of the project: Magnetic nanocontainers for combined hyperthermia and controlled drug release (MAGNIFYCO-228622)
Type of participation: Team member
PI: Teresa Pellegrino                                             Funding entity or bodies: FP7 European Commission CORDIS
Name of the programme: SEVENTH FRAMEWORK PROGRAMME (FP7)
Total amount: 330.000 €                                       Start-End date: 01/10/2009 - 28/02/2013 Duration: 3 years

Selected Publications

10 Most relevant publications:

  1. Berestok, T.; Guardia, P.; Du, R.; Portals, J. B.; Colombo, M.; Estradé, S.; Peiró, F.; Brock, S. L.; Cabot, A. Metal Oxide Aerogels with Controlled Crystallinity and Faceting from the Epoxide-Driven Cross-Linking of Colloidal Nanocrystals. ACS Applied Materials & Interfaces 2018, 10, 16041-16048.
  2. Berestok, T.; Guardia, P.; Blanco, J.; Nafria, R.; Torruella, P.; López-Conesa, L.; Estradé, S.; Ibáñez, M.; de Roo, J.; Luo, Z.; Cadavid, D.; Martins, J. C.; Kovalenko, M. V.; Peiró, F.; Cabot, A. Tuning Branching in Ceria Nanocrystals. Chemistry of Materials 2017, 29, 4418-4424.
  3. Baptista-Pires, L.; Orozco, J.; Guardia, P.; Merkoçi, A. Architecting Graphene Oxide Rolled-Up Micromotors: A Simple Paper-Based Manufacturing Technology. Small 2017, 14, 1702746.
  4. Sathya, A.; Guardia, P.; Brescia, R.; Silvestri, N.; Pugliese, G.; Nitti, S.; Manna, L.; Pellegrino, T. CoxFe3–xO4 Nanocubes for Theranostic Applications: Effect of Cobalt Content and Particle Size. Chemistry of Materials 2016, 28, 1769-1780.
  5. Carregal-Romero, S.; Guardia, P.; Yu, X.; Hartmann, R.; Pellegrino, T.; Parak, W. J. Magnetically triggered release of molecular cargo from iron oxide nanoparticle loaded microcapsules. Nanoscale 2015, 7, 570-576.
  6. Guardia, P.; Riedinger, A.; Kakwere, H.; Gazeau, F.; Pellegrino, T.: Magnetic Nanoparticles for Magnetic Hyperthermia and Controlled Drug Delivery. In Bio- and Bioinspired Nanomaterials; Wiley-VCH Verlag GmbH & Co. KGaA, 2014; pp 139-172.
  7. Riedinger, A.; Guardia, P.; Curcio, A.; Garcia, M. A.; Cingolani, R.; Manna, L.; Pellegrino, T. Subnanometer Local Temperature Probing and Remotely Controlled Drug Release Based on Azo-Functionalized Iron Oxide Nanoparticles. Nano Letters 2013, 13, 2399-2406.
  8. Guardia, P.; Korobchevskaya, K.; Casu, A.; Genovese, A.; Manna, L.; Comin, A. Plasmon Dynamics in Colloidal Au2Cd Alloy–CdSe Core/Shell Nanocrystals. ACS Nano 2013, 7, 1045-1053.
  9. Guardia, P.; Di Corato, R.; Lartigue, L.; Wilhelm, C.; Espinosa, A.; Garcia-Hernandez, M.; Gazeau, F.; Manna, L.; Pellegrino, T. Water-Soluble Iron Oxide Nanocubes with High Values of Specific Absorption Rate for Cancer Cell Hyperthermia Treatment. ACS Nano 2012, 6, 3080-3091.
  10. Guardia, P.; Pérez-Juste, J.; Labarta, A.; Batlle, X.; Liz-Marzán, L. M. Heating rate influence on the synthesis of iron oxide nanoparticles: The case of decanoic acid. Chemical Communications 2010, 46, 6108-6110.

Awards

  • TECNIOSPRING-MarieCurie fellow(TECSPR16-1-0082) 115500€ 01/09/2017-31/08/2018
  • Mariecurie IF seal of excellence 12/2016
  • TECNIOSPRING-MarieCurie fellow(TECSPR14-1-0053) 96378€ 01/10/2015-1/09/2016
  • QualityNano Transnational Access (ICN-TAF-166) 5000 € 14/10/2013-0/10/2013

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I numeri di IIT

L’Istituto Italiano di Tecnologia (IIT) è una fondazione di diritto privato - cfr. determinazione Corte dei Conti 23/2015 “IIT è una fondazione da inquadrare fra gli organismi di diritto pubblico con la scelta di un modello di organizzazione di diritto privato per rispondere all’esigenza di assicurare procedure più snelle nella selezione non solo nell’ambito nazionale dei collaboratori, scienziati e ricercatori ”.

IIT è sotto la vigilanza del Ministero dell'Istruzione, dell'Università e della Ricerca e del Ministero dell'Economia e delle Finanze ed è stato istituito con la Legge 326/2003. La Fondazione ha l'obiettivo di promuovere l'eccellenza nella ricerca di base e in quella applicata e di favorire lo sviluppo del sistema economico nazionale. La costruzione dei laboratori iniziata nel 2006 si è conclusa nel 2009.

Lo staff complessivo di IIT conta circa 1440 persone. L’area scientifica è rappresentata da circa l’85% del personale. Il 45% dei ricercatori proviene dall’estero: di questi, il 29% è costituito da stranieri provenienti da oltre 50 Paesi e il 16% da italiani rientrati. Oggi il personale scientifico è composto da circa 60 principal investigators, circa 110 ricercatori e tecnologi di staff, circa 350 post doc, circa 500 studenti di dottorato e borsisti, circa 130 tecnici. Oltre 330 posti su 1400 creati su fondi esterni. Età media 34 anni. 41% donne / 59 % uomini.

Nel 2015 IIT ha ricevuto finanziamenti pubblici per circa 96 milioni di euro (80% del budget), conseguendo fondi esterni per 22 milioni di euro (20% budget) provenienti da 18 progetti europei17 finanziamenti da istituzioni nazionali e internazionali, circa 60 progetti industriali

La produzione di IIT ad oggi vanta circa 6990 pubblicazioni, oltre 130 finanziamenti Europei e 11 ERC, più di 350 domande di brevetto attive, oltre 12 start up costituite e altrettante in fase di lancio. Dal 2009 l’attività scientifica è stata ulteriormente rafforzata con la creazione di dieci centri di ricerca nel territorio nazionale (a Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) e internazionale (MIT ed Harvard negli USA) che, unitamente al Laboratorio Centrale di Genova, sviluppano i programmi di ricerca del piano scientifico 2015-2017.

IIT: the numbers

Istituto Italiano di Tecnologia (IIT) is a public research institute that adopts the organizational model of a private law foundation. IIT is overseen by Ministero dell'Istruzione, dell'Università e della Ricerca and Ministero dell'Economia e delle Finanze (the Italian Ministries of Education, Economy and Finance).  The Institute was set up according to Italian law 326/2003 with the objective of promoting excellence in basic and applied research andfostering Italy’s economic development. Construction of the Laboratories started in 2006 and finished in 2009.

IIT has an overall staff of about 1,440 people. The scientific staff covers about 85% of the total. Out of 45% of researchers coming from abroad 29% are foreigners coming from more than 50 countries and 16% are returned Italians. The scientific staff currently consists of approximately 60 Principal Investigators110 researchers and technologists350 post-docs and 500 PhD students and grant holders and 130 technicians. External funding has allowed the creation of more than 330 positions . The average age is 34 and the gender balance proportion  is 41% female against 59% male.

In 2015 IIT received 96 million euros in public funding (accounting for 80% of its budget) and obtained 22 million euros in external funding (accounting for 20% of its budget). External funding comes from 18 European Projects, other 17 national and international competitive projects and approximately 60 industrial projects.

So far IIT accounts for: about 6990 publications, more than 130 European grants and 11 ERC grants, more than 350 patents or patent applications12 up start-ups and as many  which are about to be launched. The Institute’s scientific activity has been further strengthened since 2009 with the establishment of 11 research nodes throughout Italy (Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) and abroad (MIT and Harvard University, USA), which, along with the Genoa-based Central Lab, implement the research programs included in the 2015-2017 Strategic Plan.