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Marco Pagani Write a Message

Post Doc
Postdoctoral Research Fellow

About

Job Experience

2016-ongoing: Postdoctoral research fellow at the Functional Neuroimaging Laboratory of the Istituto Italiano di Tecnologia, Rovereto (TN) within a project aimed at mapping putative large scale brain network dysfunctions associated to autism-causing genetic mutations.

2013-2016: Doctoral researcher at the Functional Neuroimaging Laboratory of the Istituto Italiano di Tecnologia, Rovereto (TN). My research project focussed on the development and application of image processing tools to structural MRI data to map large scale gray-matter volumes and covariance networks in the mouse brain.

2010-2013: Junior researcher at the Coma Research Centre coordinated by the Neurology, Public Health and Disability Unit of the Neurological Institute Carlo Besta IRCCS Foundation, Milan (MI). My research focused on studying the disability of patients in vegetative and minimally conscious state and the quality of life of their caregivers.

2010: Research assistant at the Biosignal Analysis Centre of Experimental Neurology, Vita-Salute San Raffaele Hospital, Milan (MI). My research focused on bridging neuropsychological assessment and diffusion weighted imaging data in patients with multiple sclerosis.

 

Other Activities

2015-2016: Collaborator of the start-up R.A.W Ltd in a project aimed to provide neurosurgeons with 3d reconstruction of segmented MRI brain images for tumour surgery.

2013-2017: Collaborator as exam committee member in Cognitive Neuroscience and Neuropsychology at eCampus University in Novedrate (CO).

 

Academic Education

2013-2016: PhD in Cognitive and Brain Sciences, Center for Mind and Brain Sciences, University of Trento (TN) with a scholarship awarded by Istituto Italiano di Tecnologia. 

2012-2013: MSc in Cognitive Neuroscience at Vita-Salute San Raffaele University in Milan (MI), awarded with full marks.

2008-2009: MSc in Cognitive and Clinical Neuroscience at Goldsmiths College - University of London (UK), achieved with distinction.

2004-2007: Bachelor’s degree in Psychology at Vita-Salute San Raffaele University in Milan (MI), awarded with full marks.

Projects

2016-ongoing: Collaborator within the project "Neurobiological basis of connectivity alterations in autism" supported by SFARI Foundation.

2013-2016:  Phd scholarship “Investigating the mouse brain connectome with MRI” awarded by Istituto Italiano di Tecnologia.

2010-2013: Collaborator within the project "Start-up Coma Research Center" supported by Regione Lombardia.

Selected Publications

Publications in Journals

  1. Pagani M, Bifone A, Gozzi A (2016). Networks of anatomical covariance in the mouse brain, NeuroImage, 129:55-63.
  2. Pagani M, Damiano M, Galbusera A, Tsaftaris SA, Gozzi A (2016). Semi-automated registration-based volumetric labelling, voxel based morphometry and cortical thickness mapping of the mouse brain, J Neurosci Meth, 267:62-73.
  3. Cutuli D, Pagani M, Caporali P, Galbusera A, Laricchiuta D, Foti F, Neri C, Spalletta G, Caltagirone C, Petrosini L, Gozzi A. (2016). Effects of omega-3 fatty acid supplementation on cognitive functions and neural substrates: a voxel-based morphometry study in aged mice, Front Aging Neurosci, 8:38.
  4. Lassi G, Priano L, Maggi S, Garcia-Garcia C, Balzani E, El-Assawy N, Pagani M, Tinarelli F, Giardino D, Mauro A, Peters J, Gozzi A, Grugni G, Tucci V. (2015). Deletion of the Snord116 Alters Sleep in Mice and Patients with Prader-Willi Syndrome. Sleep 9: 637-44.
  5. Pagani M, Leonardi M, Covelli V, Giovannetti AM, Sattin D (2014). Risk factors for mortality in 600 patients in vegetative and minimally conscious states. J Neurol, 261:1144-52.
  6. Pagani M, Giovannetti AM, Covelli V, Sattin D, Leonardi M (2014). Caregiving for patients in vegetative and minimally conscious states: perceived burden as a mediator in caregivers' expression of needs and symptoms of depression and anxiety. J Clin Psychol Med Settings, 21:214-22.
  7. Schiavolin S, Quintas R, Pagani M, Brock S, Acerbi F, Visintini S, Cusin A, Schiariti M, Broggi M, Ferroli P, Leonardi M (2014). Quality of Life, Disability, Well-Being, and Coping Strategies in Patients Undergoing Neurosurgical Procedures: Preoperative Results in an Italian Sample. ScientificWorldJournal, 2014:790387.
  8. Sattin D, Covelli V, Pagani M, Giovannetti AM, Raggi A, Meucci P, Cerniauskaite M, Quintas R, Schiavolin S, Leonardi M. (2014). Do diagnostic differences between vegetative state and minimally conscious state patients correspond to differences in functioning and disability profiles? Results from an observational multi-center study on patients with DOC. Eur J Phys Rehabil Med, 50:309-21.
  9. Raggi A, Covelli V, Pagani M, Meucci P, Martinuzzi A, Buffoni M, Russo E, Leonardi M (2014). Sociodemographic features and diagnoses as predictors of severe disability in a sample of adults applying for disability certification, Int J Rehabil Res, 37:180-6.
  10. Pagani M, Giovannetti AM, Covelli V, Sattin D, Raggi R, Leonardi M (2013). Physical and Mental Health, Anxiety and Depressive Symptoms in Caregivers of Patients in Vegetative State and Minimally Conscious State, Clin Psychol Psychother, 21:420-6.
  11. Sattin D, Pagani M, Covelli V, Giovannetti AM, Leonardi M (2013). The Italian version of the Nociception Coma Scale, Int J Rehabil Res, 36:182-6.
  12. Leonardi M, Pagani M, Covelli V, Sattin D, Raggi, A (2013). Burnout in healthcare professionals working with patients with disorders of consciousness, Work, 45:349-56.
  13. Leonardi M, Sattin D, Giovannetti AM, Pagani M, Strazzer S, Villa F, Martinuzzi A, Buffoni M, Castelli E, Lispi ML, Trabacca A, Gennaro L & Raggi A. (2012) Functioning and disability of children and adolescents in a vegetative state and a minimally conscious state: identification of ICF-CY-relevant categories. Int J Rehabil Res, 35:352-9.
  14. Quintas R, Raggi A, Giovannetti AM, Pagani M, Sabariego C, Cieza A, Leonardi M. (2012). Psychosocial difficulties in people with epilepsy: A systematic review of literature from 2005 until 2010. Epilepsy Behav, 25:60-7.
  15. Giovannetti AM, Leonardi M, Pagani M, Sattin D, Raggi A (2012). Burden of caregivers of patients in Vegetative State and Minimally Conscious State. Acta Neurol Scand, 127:10-8.
  16. Leonardi M, Giovannetti AM, Pagani M, Raggi A, Sattin D (2012). Burden and needs of 487 caregivers of patients in vegetative state and in minimally conscious state: Results from a national study. Brain Inj, 26:1201-10.
  17. Giovannetti A, Pagani M, Sattin, D, Covelli V, Raggi A, Strazzer S, Castelli E, Trabacca A, Martinuzzi A, Leonardi M (2012). Children in vegetative state and minimally conscious state: patients’ condition and caregivers’ burden. ScientificWorldJournal, 2012:232149.
  18. Alvarez AS, Pagani M, Meucci P (2011). The clinical application of the biopsychosocial model in mental health: A research critique. Am J Phys Med Rehabil, 91:S173-80.
  19. Leonardi M, Raggi A, Pagani M, Carella F, Soliveri P, Albanese A, Romito L (2011). Relationships between disability, quality of life and prevalence of non-motor symptoms in Parkinson’s disease, Parkinsonism Relat Disord, 18:35-9.

Conference Proceedings

  1. Pagani M, Damiano M, Galbusera A, Tsaftaris SA, Gozzi A (2016). An automated pipeline for mouse brain morphometric MRI. 24th Annual Meeting of the ISMRM, Singapore (SGP).
  2. Pagani M, Bifone A, Gozzi A (2016). Gray matter networks of the mouse brain. 24th Annual Meeting of the ISMRM, Singapore (SGP).
  3. Bertero A, Pagani M, David G, Liska A, Galbusera A, Pasqualetti M, Gozzi A (2016). Default-mode network hypo-connectivity in a mouse model of human chromosome 16p11.2 micro-deletion. ISMRM, 24th Annual Meeting of the ISMRM, Singapore (SGP).
  4. Pesoli M, Cutuli D, Pagani M, Caporali P, Galbusera A, Laricchiuta D, Foti F, Neri C, Spalletta G, Caltagirone C, Petrosini L, Gozzi A (2016). Effects of omega-3 fatty acid supplementation on cognitive functions and neural substrates: a voxel-based morphometry study in aged mice. 10th FENS Forum of Neuroscience, Copenhagen (DK)
  5. Pagani M, Bifone A, Gozzi A (2015). Networks of anatomical covariance of the mouse brain. 32nd Annual Meeting of the ESMRMB, Edinburgh (UK).
  6. Pagani M, Cutuli D, Liska A, Caporali P, Laricchiuta D, Foti F, Neri C, Petrosini L, Gozzi A (2015). Neural and cognitive substrates of omega-3 supplementation: a VBM study in aged mice. ISMRM Italian Chapter 2015 Meeting, Verona (ITA).
  7. Pagani M, Bifone A, Gozzi A (2015). Structural covariance networks in the mouse brain. Images of the Mind, Milano (ITA).
  8. Michetti C, Morini M, Caruso A, Sabbioni M, Pagani M, Gergely D, Blesa M, Gozzi A, Benfenati F,  Scattoni ML (2015). Behavioural and neuroanatomical characterisation of synapsin-II mouse. 65esimo Congresso Nazionale della Società Italiana di Fisiologia, Genova (ITA).
  9. Pagani M, Cutuli D, Liska A, Caporali P, Laricchiuta D, Foti F, Neri C, Petrosini L, Gozzi A (2014). Neural and cognitive substrates of omega-3 supplementation: a VBM study in aged mice. 23rd Annual Meeting of the ISMRM, Toronto (CA).

Awards

2016: Magna cum laude for the poster “Pagani M, Bifone A, Gozzi A. Gray matter networks of the mouse brain.” at ISMRM in Singapore.

2016: Magna cum laude for the poster “Pagani M, Damiano M, Galbusera A, Tsaftaris SA, Gozzi A. An automated pipeline for mouse brain morphometric MRI.” at ISMRM in Singapore.

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I numeri di IIT

L’Istituto Italiano di Tecnologia (IIT) è una fondazione di diritto privato - cfr. determinazione Corte dei Conti 23/2015 “IIT è una fondazione da inquadrare fra gli organismi di diritto pubblico con la scelta di un modello di organizzazione di diritto privato per rispondere all’esigenza di assicurare procedure più snelle nella selezione non solo nell’ambito nazionale dei collaboratori, scienziati e ricercatori ”.

IIT è sotto la vigilanza del Ministero dell'Istruzione, dell'Università e della Ricerca e del Ministero dell'Economia e delle Finanze ed è stato istituito con la Legge 326/2003. La Fondazione ha l'obiettivo di promuovere l'eccellenza nella ricerca di base e in quella applicata e di favorire lo sviluppo del sistema economico nazionale. La costruzione dei laboratori iniziata nel 2006 si è conclusa nel 2009.

Lo staff complessivo di IIT conta circa 1440 persone. L’area scientifica è rappresentata da circa l’85% del personale. Il 45% dei ricercatori proviene dall’estero: di questi, il 29% è costituito da stranieri provenienti da oltre 50 Paesi e il 16% da italiani rientrati. Oggi il personale scientifico è composto da circa 60 principal investigators, circa 110 ricercatori e tecnologi di staff, circa 350 post doc, circa 500 studenti di dottorato e borsisti, circa 130 tecnici. Oltre 330 posti su 1400 creati su fondi esterni. Età media 34 anni. 41% donne / 59 % uomini.

Nel 2015 IIT ha ricevuto finanziamenti pubblici per circa 96 milioni di euro (80% del budget), conseguendo fondi esterni per 22 milioni di euro (20% budget) provenienti da 18 progetti europei17 finanziamenti da istituzioni nazionali e internazionali, circa 60 progetti industriali

La produzione di IIT ad oggi vanta circa 6990 pubblicazioni, oltre 130 finanziamenti Europei e 11 ERC, più di 350 domande di brevetto attive, oltre 12 start up costituite e altrettante in fase di lancio. Dal 2009 l’attività scientifica è stata ulteriormente rafforzata con la creazione di dieci centri di ricerca nel territorio nazionale (a Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) e internazionale (MIT ed Harvard negli USA) che, unitamente al Laboratorio Centrale di Genova, sviluppano i programmi di ricerca del piano scientifico 2015-2017.

IIT: the numbers

Istituto Italiano di Tecnologia (IIT) is a public research institute that adopts the organizational model of a private law foundation. IIT is overseen by Ministero dell'Istruzione, dell'Università e della Ricerca and Ministero dell'Economia e delle Finanze (the Italian Ministries of Education, Economy and Finance).  The Institute was set up according to Italian law 326/2003 with the objective of promoting excellence in basic and applied research andfostering Italy’s economic development. Construction of the Laboratories started in 2006 and finished in 2009.

IIT has an overall staff of about 1,440 people. The scientific staff covers about 85% of the total. Out of 45% of researchers coming from abroad 29% are foreigners coming from more than 50 countries and 16% are returned Italians. The scientific staff currently consists of approximately 60 Principal Investigators110 researchers and technologists350 post-docs and 500 PhD students and grant holders and 130 technicians. External funding has allowed the creation of more than 330 positions . The average age is 34 and the gender balance proportion  is 41% female against 59% male.

In 2015 IIT received 96 million euros in public funding (accounting for 80% of its budget) and obtained 22 million euros in external funding (accounting for 20% of its budget). External funding comes from 18 European Projects, other 17 national and international competitive projects and approximately 60 industrial projects.

So far IIT accounts for: about 6990 publications, more than 130 European grants and 11 ERC grants, more than 350 patents or patent applications12 up start-ups and as many  which are about to be launched. The Institute’s scientific activity has been further strengthened since 2009 with the establishment of 11 research nodes throughout Italy (Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) and abroad (MIT and Harvard University, USA), which, along with the Genoa-based Central Lab, implement the research programs included in the 2015-2017 Strategic Plan.