I am a neuroscientist with a background in Mathematics. I have experience in both computational and experimental neuroscience.
Currently, I am a Marie Curie Fellow at the Centre for Neuroscience and Cognitive Systems (Trento, Italy) with Prof. Stefano Panzeri. I am developing analytical and numerical tools to expose new principles of spike encoding that bridge the gap between single cell and population information processing.
I previously worked with Prof. Rodrigo Quiroga at the Centre for Systems Neuroscience in Leicester (UK). During this period I built a 3D virtual environment for mice and set up a protocol for a decision making task.
Before that, I did my PhD at Instituto de Neurociencias in Alicante (Spain) with Dr. Miguel Maravall and Dr. Luis Martínez. In the course of my PhD I acquired both computational (modelling and data analysis) and experimental experience (2-photon microscopy).
Below, you can find my main publications, links to the places where I previously worked and to two blogs I have written (and still write). If you want to know more about my research experience you can click on the CV link on the top of this page. Thanks for visiting!
ETIC: Encoding and Transmission of Information in the Mouse Somatosensory Cortex
A major challenge in neuroscience is to understand how neurons encode information. Optogenetics techniques provide the opportunity of controlling neuronal activity with high temporal and spatial resolution and thus testing causally the role of a specific encoding strategy. However, to enable us to crack the neural code, these optical approaches need to be complemented by theoretical developments that:
My project has as its main goal to develop a novel theoretical framework to address these issues and help understanding how the mammalian cortex encodes sensory information, using the mouse somatosensory cortex as an experimental model. In particular, I am devising computational techniques aimed at characterizing the encoding and transmission of information in layer IV and then in one of its main targets: layer II/III. Specifically, I use Non-Negative Matrix Factorization methods to characterize how large-scale populations of layer IV encode whisker information.
Further, I have developed, in colaboration with Dr. Arno Onken, Dr. Houman Safaai and Prof. Stefano Panzeri, a jitter based method to decompose the electrophysiological responses of layer II/III neurons into independently contributing temporal scales and establish which whisker-informative components of layer IV population activity are transmitted to the responses of layer 2/3 neurons.
The project is carried on in tight collaboration with Tommaso Fellin's laboratory in Genova, where the experiments are performed by Dr. Marco Brondi.