All Publications
2025
Intze A., Temperini M.E., Rupert J., Polito R., Veber A., Puskar L., Schade U., Ortolani M., Zacco E., Tartaglia G.G., Giliberti V.
Effect of RNA on the supramolecular architecture of α-synuclein fibrils
Biophysical Journal
Article
Journal
2025
Zappone S., Perego E., Rupert J., Zacco E., Slenders E., Tartaglia G. G., Vicidomini G.
The role of RNA in the nanoscale organization of α-synuclein phase separation
NAR Molecular Medicine, vol. 2, (no. 2)
Article
Journal
2024
Spence H., Waldron F.M., Saleeb R.S., Brown A.-L., Rifai O.M., Gilodi M., Read F., Roberts K., Milne G., Wilkinson D., O'Shaughnessy J., Pastore A., Fratta P., Shneider N., Tartaglia G.G., Zacco E., Horrocks M.H., Gregory J.M.
RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS
Acta Neuropathologica, vol. 147, (no. 1)
2024
Zacco E., Broglia L., Kurihara M., Pastore A., Gustincich S., Plath K., Nagakawa S., Cerase A., Sanchez de Groot N., Tartaglia G.G.
RNA: The Unsuspected Conductor in the Orchestra of Macromolecular Crowding
Chemical Reviews
2024
Panei F.P., Di Rienzo L., Zacco E., Armaos A., Tartaglia G.G., Ruocco G., Milanetti E.
Synchronized motion of interface residues for evaluating protein–RNA complex binding affinity: Application to aptamer-mediated inhibition of TDP-43 aggregates
Protein Science, vol. 33, (no. 12)
Scientific Talks
2022
Zacco E.
Amino acid-glycan conjugates as protein aggregation inhibitors: A spoonful of sugar against proteinopathies
Neuroglycoprotein in health and disease
Workshop/Symposium
2022
Zacco E.
“Out of phase”: A tale of proteins and RNA in biological condensation
Universita degli Studi di Milano - Bicocca
Institute
2021
Zacco E.
Exploring early events in protein phase separation with RNA aptamers
Institut de Neurociencies, Universitat Autonoma de Barcelona
Institute
2021
Zacco E.
Exploring early events in protein phase separation with RNA aptamers
Universita degli Studi di Roma La Sapienza
Institute
2021
Zacco E.
Exploring protein phase separation in living cells with RNA aptamers
AGI2021
Conference
Awards and Achievements
2023
Tartaglia G., Zacco E.
Target ALS grant
2022
Zacco E., Tartaglia GG., Horrocks M., Gregory J., Schneider N.
Probing RNA-binding protein aggregates at the nanoscale using in-silico-designed aptamers.
2019
Zacco E.
MINDED Fellowship
2018
Zacco E.
Daniel Turnberg travel fellowship
2017
Zacco E.
EMBO Short-term fellowship
Editorships
2021
Zacco E.
Advanced Spectroscopic Methods to Study Biomolecular Structure and Dynamics
2019
Zacco E.
Protein and RNA Networks and Biology, section of Frontiers in Molecular Biosciences
2018
Zacco E.
Protein Misfolding in Ageing and Neurodegeneration, research topic in Frontienrs in Molecular Bioscience
Organized Events
2018
Zacco E., Pastore A.
Protein misfolding in ageing and neurodegeneration: from basic biology to drug development
Colleagues of RNA Systems Biology
