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Andrea Cavalli

Senior Researcher - Principal Investigator
Computational and Chemical Biology
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Biografia

Andrea Cavalli is PI of Computational & Chemical Biology.

Prof. Cavalli received his PhD in Pharmaceutical Sciences from the University of Bologna in 1999 and did postdoctoral work at SISSA (Trieste, Italy) and ETH (Zurich, Switzerland), where he also was a visiting scientist.

Congress presentations and seminars

Prof. Cavalli has delivered over 130 invited lectures and seminars at international congresses and at prestigious national and international institutions.

Patents and technology transfer activity

Prof. Cavalli is co-inventor in 11 international PCT patents and patent applications, and he is co-founder of the high-tech start-up company BiKi Technologies, which collaborates with several pharmaceutical companies in Europe and in the USA.

Committees and editorial activities

Prof. Cavalli has been a member of the scientific and/or organizing committees of several national and international congresses and symposia, including CECAM Workshops in Lausanne and Genoa, EuroQSAR Congress in Vienna and Thessaloniki, Drug Design and Medicinal Chemistry Congress in Boston and Berlin, etc. He was nominated chairman of the 21st edition of the International Symposium EuroQSAR, which was held in Italy (Verona) in Sept. 2016. He is chair of the international scientific organization QSAR, Chemoinformatic and Modeling Society (QCMS former QSAR Society). Prof. Cavalli is member of the Editorial Board of numerous international scientific journals and he has been reviewer and committee member for several international funding agencies (EU, Austria, Switzerland, France, USA, Israel, etc.).

Education

Title: PhD in Pharmaceutical Sciences
Institute: ALMA MATER STUDIORUM UNIVERSITA' DI BOLOGNA
Location: Bologna
Country: Italy
From: 1996 To: 1999

Experience External

Title: Head of the Computational Genomics Group
Institute: ISTITUTO ITALIANO DI TECNOLOGIA- CMP3 AOSTA
Location: Aosta
Country: Italy
From: 2019 To: null

Title: Full Professor
Institute: ALMA MATER STUDIORUM UNIVERSITA' DI BOLOGNA
Location: Bologna
Country: Italy
From: 2014 To: null

All Publications
2024
Myers S.H., Poppi L., Rinaldi F., Veronesi M., Ciamarone A., Previtali V., Bagnolini G., Schipani F., Ortega Martinez J.A., Girotto S., Di Stefano G., Farabegoli F., Walsh N., De Franco F., Roberti M., Cavalli A.
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer
European Journal of Medicinal Chemistry, vol. 265
Article Journal
2024
Bassi P.R.A.S., Dertkigil S.S.J., Cavalli A.
Improving deep neural network generalization and robustness to background bias via layer-wise relevance propagation optimization
Nature Communications, vol. 15, (no. 1)
Article Journal
2023
Poppi L., Myers S.H., Previtali V., Rinaldi F., Farabegol F., Di Stefano G., Walsh N., Roberti M., Cavalli A.
A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer
EACR
Poster Conference
2023
Rocutto L., Maronese M., Traversa F.L., Decherchi S., Cavalli A.
Assessing the Effectiveness of Non-Turing Computing paradigms
IEEE Access
Article Journal
2023
Demuro S., Di Martino R.M.C., Sauvey C., Tripathi S.K., Ortega J. A., Russo D., Penna I., Myers S. H., Bandiera T., Girotto S., Abagyan R., Cavalli A.
Design and synthesis of triple protein kinase inhibitors: paving the way towards novel CNS tools to reverse the aberrant tau phosphorylation
ACS Spring 2023 meeting
Poster Conference