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Silvia Dante

Chief Technician

Research Line

Nanoscopy & NIC@IIT


IIT Central Research Labs Genova


via Morego 30
+39 010 2896 541
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Silvia Dante graduated in Physics at the University of Genoa (Italy) in 1990, with a Master thesis entitled ‘Polymerizable monolayers at the air/water interface studied by epifluorescence microscopy’. From 1990 to 1994 she accomplished her PhD studies in Biochemisty and Biophysics at the Institute of Physical Science of University of Ancona, submitting a thesis on the ‘Characterization of Langmuir and Langmuir-Blodgett films of Archaeal lipids by scattering techniques’. After a postdoc year at the University of Ancona and a one year contract as adjunt professor in Biophysics at the Faculty of Science in the same University, she moved to the U.S. From 1996 to 1998 she was postdoc fellow of CPIMA (Center of Polymer Interface and Macromolecular Assemblies) at University of California, Davis and at Stanford Universityto investigate the nucleation of iron nanoparticles with a biomimetic approach. From 1998 to 2008 she was employed at the Helmoltz-Zentrum Berlin für Materialien und Energie in Berlin (Germany) as beam scientist, responsible for a neutron diffractometer dedicated to the investigation of biologicalmembranes. She performed research mainly in the localization of medically relevant peptides, such as beta-amyloid, in model membranes.

Since August 2008, she has a team-leader position at Italian Institute of Technology (IIT), shared between the Nanophysics and the NBT departments. The research projects focus on the characterization of membrane and cellular adhesion on patterned and/or biofunctionalized surfaces.

She is co-author of about 80 peer-reviewed international papers and of others in conference proceedings; she is herself is referee in many highly ranked scientific journal. She is a member of national (SIF, SISN) and international societies (Biophysical Society).

Silvia Dante has a very interdisciplinary background and a strong experimental background in the structural characterization of biological systems. She canuse independently the following analytical and/or spectroscopic techniques: X-rays and neutron diffraction and reflectivity, FT-IR, differential scanning calorimetry, fluorescence spectroscopy, QCM-D.


Selected Publications



80.  S Seghezza, S Dante, A Diaspro, C Canale High resolution nanomechanical characterization of multi‐domain model membranes by fast Force Volume Journal of Molecular Recognition 28 (12), 742-750, 2015
79. C Toccafondi, S Dante, A P Reverberi, M Salerno, Biomedical Applications of Anodic Porous Alumina
Current Nanoscience 11 (5), 572-580, 2015
78. C Toccafondi, R La Rocca, A Scarpellini, M Salerno, G Das, S Dante, Thin nanoporous alumina-based SERS platform for single cell sensing Applied Surface Science 351, 738-745, 2015
77. A Accardo, V Shalabaeva, B Hesse, M Cotte, R Krahne, C Riekel, S Dante, Synchrotron μ-FTIR highlights amyloid-β conformational changes under the effect of surface wettability and external agents Vibrational Spectroscopy 80, 30-35, 2015
76. A Accardo, V Shalabaeva, E Di Cola, M Burghammer, R Krahne, C Riekel, S.Dante, Superhydrophobic Surfaces Boost Fibril Self-Assembly of Amyloid β Peptides ACS applied materials & interfaces 7 (37), 20875-20884, 2015
Microscopy and Microanalysis 21 (S3), 2351-2352, 2015
74. A Accardo, V Shalabaeva, M Cotte, B Hesse, M Burghammer, C Riekel, S.Dante, The role of surface wettability and environmental conditions in Amyloid beta conformational changes FEBS JOURNAL 282, 324-325, 2015
73. G Marinaro, A Accardo, N Benseny-Cases, M Burghammer, S.Dante, C.Riekel., Probing droplets with biological colloidal suspensions on smart surfaces by synchrotron radiation micro-and nano-beams Optics and Lasers in Engineering, 2015
72. L Ceseracciu, JA Heredia-Guerrero, S Dante, A Athanassiou, IS Bayer, Robust and biodegradable elastomers based on corn starch and polydimethylsiloxane (PDMS)ACS applied materials & interfaces 7 (6), 3742-3753, 2015
71. S Seghezza, A Diaspro, C Canale, S Dante, Cholesterol Drives Aβ (1–42) Interaction with Lipid Rafts in Model Membranes Langmuir 30 (46), 13934-13941, 
70. C Toccafondi, S Thorat, R La Rocca, A Scarpellini, M Salerno, S Dante, G.Das, Multifunctional Substrates of Thin Porous Alumina for cell sensing Journal of Materials Science: Materials in Medicine 25 (10), 2411-2420, 2014

69. C Toccafondi, R La Rocca, G Das, S Dante, M Salerno Thin Substrates of Anodic Porous Alumina for Living Cells Sensing Aluminum Anodizers Council-2014

68. A.Accardo, V.Shalabaeva, M.Cotte, M.Burghammer, R.Krahne, C.Riekel,S.Dante Amyloid β peptide conformational changes in the presence of a lipidmembrane system Langmuir 30 (11) (2014) 31913198

67. C.Toccafondi, S.Thorat, R. La Rocca, A.Scarpellini, M.Salerno, S.Dante,G.Das Multifunctional substrates of thin porous alumina for cell biosensors,Journal of Material Science: Materials in Medicine, (2014) 1-10.

66. C.Canale, S.Seghezza, S.Vilasi, R.Carrotta, D.Bulone, A.Diaspro,P.Sanbiagio, S.Dante, Different effects of Alzheimer's peptide Aβ(1-40)oligomers and fibrils on supported lipid membranes Biophysical Chemistry,182 (2014) 23-29.

65. M.Lorenzoni, F.Brandi, S.Dante, A.Giugni, B.Torre, Simple and effective graphene laser processing for neuron patterning application, ScientificReports 3: 1954(2013).

64. A.Petrelli, E.Marconi, M.Salerno, D.De Pietri Tonelli, L.Berdondini, S.Dante,Nano volume drop patterning for rapid on-chip neuronal connect-abilityassays, Lab-on-a-chip, 13 (2014) 4419-4429.

63. K.Bagga, A.Barchanski, R.Intartaglia, S.Dante, R.Marotta, A.Diaspro,C.L.Sajti, F.Brandi, Laser-assisted synthesis of Staphylococcus aureusprotein-capped silicon quantum dots as bio-functional nanoprobes LaserPhysics Letters 10 (6) (2013) 065603

62. C.Canale, A.Petrelli, M.Salerno, A.Diaspro, S.DanteA new quantitative experimental approach to investigate single cell adhesion on multifunctional substrates, Biosensor and Bioelectronics, 48 (2013) 172-179.

61. M. Moretti, C.Canale, M.Francardi, S.Dante, F.De Angelis, E. Di Fabrizio, AFM characterization of biomolecules in physiological environment by anadvanced nanofabrication probe Microscopy Research and Technique 75(2012) 1723-1731.

60. A.Accardo, V.Shalabaeva, M.Cotte, M.Burghammer, R.Krahne, C.Riekel, S.Dante Amyloid  peptide conformational changes in the presence of a lipid membrane system Langmuir 30 (11) (2014) 3191- 3198.

59. C.Toccafondi, S.Thorat, R. La Rocca, A.Scarpellini, M.Salerno, S.Dante, G.Das Multifunctional substrates of thin porous alumina for cell biosensors, Journal of Material Science: Materials in Medicine, (2014) 1-10.

58. C.Canale, S.Seghezza, S.Vilasi, R.Carrotta, D.Bulone, A.Diaspro, P.Sanbiagio, S.Dante, Different effects of Alzheimer's peptide A(1-40)  oligomers and fibrils on supported lipid membranes  Biophysical Chemistry, 182 (2014) 23-29.

57. M.Lorenzoni, F.Brandi, S.Dante, A.Giugni, B.Torre, Simple and   effective graphene laser processing for neuron patterning application, Scientific Reports 3: 1954(2013).

56. A.Petrelli, E.Marconi, M.Salerno, D.De Pietri Tonelli, L.Berdondini, S.Dante, Nano volume drop patterning for rapid on-chip neuronal connect-ability assays, Lab-on-a-chip, 13 (2014) 4419-4429.

55. K.Bagga, A.Barchanski, R.Intartaglia, S.Dante, R.Marotta, A.Diaspro, C.L.Sajti, F.Brandi, Laser-assisted synthesis of Staphylococcus aureus protein-capped silicon quantum dots as bio-functional nanoprobes Laser Physics Letters 10 (6) (2013) 065603.

54. C.Canale, A.Petrelli, M.Salerno, A.Diaspro, S.Dante, A new quantitative experimental approach to investigate single cell adhesion on multifunctional substrates, Biosensor and Bioelectronics, 48 (2013) 172-179.

53. M. Moretti, C.Canale, M.Francardi, S.Dante, F.De Angelis, E. Di Fabrizio, AFM characterization of biomolecules in physiological environment by an advanced nanofabrication probe Microscopy Research and Technique 75  (2012) 1723-1731.

52. L.Martiradonna, L.Quarta, L.Sileo, A.Schertel, A.Maccione, A.Simi, S.Dante, A.Scarpellini, L.Berdondini, M. Di Vittorio, Beam induced deposition of 3D electrodes to improve coupling to cells, Microelectronic Engineering, 97 (2012) 365-368.

51. E.Marconi, T.Nieus, A.Maccione, P.Valente, A.Simi, M.Messa, S.Dante, P.Baldelli, L.Berdondini, F.Benfenati Emergent functional properties of neuronal networks with controlled topology PloS One 7 (4) (2012) e34648.

50. A.A.Sapalidis, F.K.Katsaros, T.A.Steriotis, N.K.Kanellopoulos, S.Dante, T.Hauss, Neutron diffraction on polymer composites- A tool for structural and orientation studies Journal of Physics: Conference Series 340 (1), (2012) 012090.

49. S.Dante, T.Hauß, R.Steitz, C.Canale, N.A. Dencher, Nanoscale structural and mechanical effects of beta-amyloid (1–42) on polymer cushioned membranes: A combined study by neutron reflectometry and AFM Force Spectroscopy Biochimica et Biophysica Acta (BBA) - Biomembranes 1808, (2011) 2646-2655.

48. A.Buchsteiner, T.Hauss, S.Dante, N.A.Dencher Alzheimer’s disease amyloid beta peptide analogue alters the pico-second dynamics of phospholipid membranes BBA-Biomembranes 1798 (2010) 1969-1976.

47. M.Salerno, N.Patra, S.Dante, A.Diaspro AFM measurement of the stiffness of layers of agarose gel patterned with polylysine Microscopy Research and Technique, 73 (2010) 982-990.

46. C.Canale, M.Jacono, A.Diaspro, S.Dante, Force spectroscopy as a tool to investigate the properties of supported lipid membranes, Microscopy Research and Technique, 73 (2010) 965-972.

45. N.Y. Ryabova, M.A.Kiselev, S.Dante, T.Hauss, A.M. Balagurov, Investigation of stratum corneum lipid membranes with free fatty acid composition by neutron diffraction, European Biophysics Journal with Biophysics Letters, 39 (2010) 1167-1176.

44. A.Schroeter, M.A. Kiselev, T.Hauß, S.Dante, R.H.H. Neubert Evidence of free fatty acid interdigitation in stratum corneum model membranes based on ceramide [AP] by deuterium labelling. Biochimica et Biophysica Acta (BBA)-Biomembranes 1788 (10), 2194-2203, 2009.

43. A.Schroeter, D.Kessner, M.A.Kiselev, T.Hauss, S.Dante, R.H.H.Neubert Basic nanostructure of stratum corneum lipid matrices based on ceramides [EOS] and [AP] : A neutron diffraction study.  Biophysical Journal 97 (4), 1104-1114 (2009).

42. H.Seelert, D.N.Dani, S.Dante, T.Hauss, F.Krause, E. Schaefer, M.Frenzel, A.Poetsch, S.Rexroth, H.J. Schwassmann, T.Suhai, J.Vonck, N.A. Dencher From protons to OXPHOS supercomplexes and Alzheimer’s disease: structure-dynamics-funtion relashionship of energy transducing membranes, Biochimica Biophysica Acta - Bioenergetics, 1787 (2009) 657-671.

41. S.Milani, D.Berti, S.Dante, T.Hauss, P.Baglioni. Intercalation of single-strand oligonucleotides between Nucleolipid Anionic Membranes: a neutron diffraction study Langmuir, 25 (2009) 4084-92.

40. D.Kessner, M.Kiselev, S.Dante, T.Hauss, P.Lersch, S.Wartewig, R.H.H. Neubert Arrangement of ceramide [EOS] in a stratum corneum lipid model matrix: new aspects revealed by neutron diffraction studies. European Biophysical Journal, 37 (2008) 989-999.

39. A.Rüttinger, M.A.Kiselev, T.Hauß, S.Dante, S.Balagurov, R.H.H. Neubert, Fatty acid interdigitation in stratum corneum model membranes: a neutron diffraction study European Biophysical Journal, 37 (2008) 759-771.

38. M.A.Kiselev, E.V. Zernyalanya, N. Ryabova, T.Hauss, S.Dante, D.Lombardo Water distribution function across the curved lipid bilayer: a SANS study Chemical Physics 345, (2008) 185-190.

37. D.Kessner, M.A. Kiselev, T. Hauß, S.Dante, S.Wartewig, R.H.H. Neubert, Localization of partially deuterated cholesterol in quaternary SC lipid model membranes: a neutron diffraction study. European Biophysical Journal, 37 (2008)1051-57.

  1. S.Milani, F.Baldelli Bombelli, D.Berti, S.Dante, T. Haub, P.Baglioni, Nucleolipid Membranes: Structure and Molecular Recognition, Journal of Physics: Condensed Matter, 10 (2008) 104212.

35. S.Dante, T.Hauß, N.A.Dencher, Membrane fusogenic activity of the Alzheimer’s peptide A(1-42) demonstrated by Small-Angle-Neutron Scattering, J.Mol.Biol, 376, (2008) 393-404.

34. F.Bringezu, S.Wen, S.Dante, T.Hauss, M.Majerowicz, A.Waring The insertion of the Antimicrobial Peptide Dicynthaurin Monomer in Model Membrane: Thermodynamics and Structural Characterization, Biochemistry, 46 (2007) 5678-86.

33. S.Dante, T.Hauß, N.A.Dencher Cholesterol inhibits the insertion of -amyloid (25-35) into phospholipids membranes European Biophysics Journal, 35 (2006) 523-31.

32. S.Milani, F. Baldelli-Bombelli, D.Berti, T.Hauss, S.Dante, P.Baglioni Structural Investigation of L phases formed by 1-Palmitoyl-2-oleoyl-phosphatidyl-nucleosides Biophysical Journal, 90 (2006) 1260-1269.

31. S.Dennison, T.Hauß, S.Dante, K.Brandemburg F.Harris, D.Phoenix Deuteration can  affect the conformational behaviour of amphiphilic alpha-helical structures.  Biophys. Chem. 119 (2006) 115-20.

30. T.Hauss, S.Dante, N.A.Dencher, T.H.Haines Localization of coenzyme Q10 in the center of a deuterated lipid membrane by neutron diffraction Biochimica et Biophysica Acta 1710 (2005) 57-62.

29. M.Kiselev, N.Ryabova, A.Balagurov, S.Dante, T.Hauss, J.Zbytovska, S.Wartewig, R.Neubert  New insight into structure and hydration of stratum corneum lipid model membrane by neutron diffraction European Biophysical Journal 34 (2005)  1030-1040.

28. S.Dennison, S.Dante, T.Hauß, K.Brandemburg F.Harris, D.Phoenix Investigation into the membrane interactions of m-Calpain domain V Biophysical Journal, 88 (2005) 3008-3017.

27. S.Dante, T.Hauß, N.A.Dencher Externally administered amyloid  peptide 25-35 and perturbation of lipid bilayers Biochemistry, 42 (2003) 13667-72.

26. D.Huster, A.Vögel, C.Katzka, H.A. Scheidt, H.Bindner, S.Dante, T.Gutberlet, O.Zschörnig, H.Waldmann, K.Arnold. Membrane insertion of a lipidated Ras Peptide studied by FTIR, solid-state NMR, and neutron diffraction spectroscopy Journal of American Chemical Society 125 (2003) 4070-4079.

25. T.Hauss, S.Dante, N.A.Dencher, T.H.Haines Squalane Is in the midplane of the lipid bilayer: implication for its function as a proton permeability barrier, Biochimica et Biophysica Acta, 1556 (2002) 149-154.

24. S.Dante, T.Hauss, N.A. Dencher amyloid 25 to 35 is intercalated in anionic and zwitterionic lipid membranes to different extents, Biophysical Journal, 83  (2002) 2610-2616.

23. D.Berti, E.Fratini, S.Dante, T.Hauß, P.Baglioni, A structural study of lamellar phases formed by nucleoside functionalized lipids Applied Physics A 74 (2002) 522-524.

22. M.J.M.Darkes, T.Hauss, S.Dante, J.P.Bradshaw, Revealing the membrane-bound structure of neurokinin A using neutron diffraction, Physica B 276-278 (2000) 505-507.

21. Z.Hou, S.Dante, N.L.Abbott, P.Stroeve Self-Assembled Monolayers on (111) Textured Electroless Gold,  Langmuir 15 (1999) 3011-3014.

20. S.Dante, Z.Hou, P.Stroeve, S.Risbud Nucleation of Oxy-Hydroxide Nanoparticles by Layer-by-Layer  Polyionic Assemblies  Langmuir., 15(1999) 2176-2182.

19. S.Dante, R.Advincula, P.Stroeve, C.W.Frank, Photoisomerization of Polyionic Layer-by-Layer Films containing Azobenzene, Langmuir, 15 (1999) 193-201.

18. H.Franz, S.Dante, Th. Wappmannsberger, W.Petry, M.DeRosa, F.Rustichelli, An X-ray Reflectivity Study of Monolayers and Bilayers of Archae Lipids on Solid Substrate, Thin Solid Films, 327-329 (1998) 52-55.

17.A.Ambrosini, G.Bossi, S.Dante, B.Dubini, L.Gobbi, L.Leone, M.G.Ponzi Bossi, G.Zolese, Lipid-drug interaction: thermodynamic and structural effects of antimicotic fluconazole on DPPC liposomes, Chemistry and Physics of Lipids 95 (1998) 37-47.

16. V.Erokhin, P.Facci, L.Gobbi, S.Dante, F.Rustichelli, C.Nicolini, Preparation of semiconductor superlattices from LB precursor, Thin Solid Films 327-329 (1998) 503-505.

15. S.Dante, M.G.Ponzi Bossi, F.Rustichelli, Langmuir Blodgett Films of Archaeal lipids: properties and perspectives, Electrical and Related Properties of Organic Solids, (1997) 431-443.

14. S.Dante, M.DeRosa, O.Francescangeli, F.Rustichelli, V.I.Troitsky, Supramolecular Ordering of Bipolar Lipids from Archae in Langmuir-Blodgett Films by Low Angle X-ray Diffraction, Thin Solid Films, 284-285 (1996) 459-463.

13. R.Rolandi, S.Dante, A.Gussoni, S.Leporatti, L.Maga, P.Tundo, Polymerized Monomolecular Films: Microscopic Structure, Viscosity, and Photopolymerization Kinetics, Langmuir,  Vol 11, N.8, (1995) 3119-3129.

12. S.Dante, M.De Rosa, E.Maccioni, A.Morana, C.Nicolini, F.Rustichelli V.I.Troitsky,   B.Yang Thermal stability of bipolar lipid Langmuir-Blodgett films by X-ray diffraction  Mol.Cryst.Liq.Cryst. 262  (1995) 191-207.

11. T.S.Berzina, V.I.Troitsky, A.Riccio, M.De Rosa, S.Dante, E.Maccioni, F.Rustichelli, P.Accossato, C.Nicolini "Application of Langmuir-Blodgett for depositing thin films of lipids from archaebacterium". Molecular Manufacturing, 77-88.

10. T.S.Berzina, V.I.Troitsky, A.Riccio, M.De Rosa, S.Dante, E.Maccioni, F.Rustichelli,   P.Accossato, C.Nicolini Langmuir-Blodgett films of bipolar lipids from thermophilic  archaebacterium  Materials Science and Engineering, C-3 (1995) 13-21.

9. G.Albertini, B.Dubini, S.Dante, R.S.Phadke M.G.Ponzi Bossi, S.Srivastava. Lipid-drug interaction: influence of antidiarroheal loperamide on model membranes Physica Medica - Vol.XI, N.1 (1995) 1-8.

8. A.Gliozzi, A.Relini, R.Rolandi, S.Dante, A.Gambacorta Organization of bipolar lipids in monolayers at the air-water interface, Thin Solid Films, 242 (1994) 208-212.

7. F.Rustichelli, S.Dante, P.Mariani, I.V.Myagkov, V.I.Troitsky Surface potential studies of monolayers of surfactants donor-acceptor molecules  Thin Solid Films, 242 (1994) 267-272.

6. S.Dante, V.Erokhin, F.Rustichelli Langmuir-Blodgett Films Built-up with Two Components Monolayers, Mol. Cryst.Liq.Cryst  43 (1994) 125-134.

5. S.Dante, B.Dubini, G.M.Guidi, F.Montecchia, M.G.Ponzi Bossi, F.Vetrano Preliminary study and structural modifications induced by extremely low frequency fields on lecithin liposomes, Physica Medica,vol IX (suppl1)(1993)  311-312.

4. S.Dante, O.Francescangeli, P.Mariani, V.Erokhin, R.Kayushina Determination of molecular packing in Immunoglobulin LB films, Physica Medica, vol IX  (suppl1) (1993) 52-55.

3.   S.Dante, V.Erokhin, F.Rustichelli On the structure of mixed Langmuir- Blodgett films, Thin Solid Films 210/211 (1992) 637-639.

2.  S.Dante, V.Erokhin, F.Rustichelli On the structure of mixed Langmuir-Blodgett films of two different fatty acid salts, Mol.Cryst.Liq. 215 (1992) 205-211.

1. R.Rolandi, S.Dante, L.Maga, M.Robello, Domains formation in polymerized monolayers revealed by fluorescence microscopy, Progr Colloid Polym Sci  84 (1991) 273-274.




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I numeri di IIT

L’Istituto Italiano di Tecnologia (IIT) è una fondazione di diritto privato - cfr. determinazione Corte dei Conti 23/2015 “IIT è una fondazione da inquadrare fra gli organismi di diritto pubblico con la scelta di un modello di organizzazione di diritto privato per rispondere all’esigenza di assicurare procedure più snelle nella selezione non solo nell’ambito nazionale dei collaboratori, scienziati e ricercatori ”.

IIT è sotto la vigilanza del Ministero dell'Istruzione, dell'Università e della Ricerca e del Ministero dell'Economia e delle Finanze ed è stato istituito con la Legge 326/2003. La Fondazione ha l'obiettivo di promuovere l'eccellenza nella ricerca di base e in quella applicata e di favorire lo sviluppo del sistema economico nazionale. La costruzione dei laboratori iniziata nel 2006 si è conclusa nel 2009.

Lo staff complessivo di IIT conta circa 1440 persone. L’area scientifica è rappresentata da circa l’85% del personale. Il 45% dei ricercatori proviene dall’estero: di questi, il 29% è costituito da stranieri provenienti da oltre 50 Paesi e il 16% da italiani rientrati. Oggi il personale scientifico è composto da circa 60 principal investigators, circa 110 ricercatori e tecnologi di staff, circa 350 post doc, circa 500 studenti di dottorato e borsisti, circa 130 tecnici. Oltre 330 posti su 1400 creati su fondi esterni. Età media 34 anni. 41% donne / 59 % uomini.

Nel 2015 IIT ha ricevuto finanziamenti pubblici per circa 96 milioni di euro (80% del budget), conseguendo fondi esterni per 22 milioni di euro (20% budget) provenienti da 18 progetti europei17 finanziamenti da istituzioni nazionali e internazionali, circa 60 progetti industriali

La produzione di IIT ad oggi vanta circa 6990 pubblicazioni, oltre 130 finanziamenti Europei e 11 ERC, più di 350 domande di brevetto attive, oltre 12 start up costituite e altrettante in fase di lancio. Dal 2009 l’attività scientifica è stata ulteriormente rafforzata con la creazione di dieci centri di ricerca nel territorio nazionale (a Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) e internazionale (MIT ed Harvard negli USA) che, unitamente al Laboratorio Centrale di Genova, sviluppano i programmi di ricerca del piano scientifico 2015-2017.

IIT: the numbers

Istituto Italiano di Tecnologia (IIT) is a public research institute that adopts the organizational model of a private law foundation. IIT is overseen by Ministero dell'Istruzione, dell'Università e della Ricerca and Ministero dell'Economia e delle Finanze (the Italian Ministries of Education, Economy and Finance).  The Institute was set up according to Italian law 326/2003 with the objective of promoting excellence in basic and applied research andfostering Italy’s economic development. Construction of the Laboratories started in 2006 and finished in 2009.

IIT has an overall staff of about 1,440 people. The scientific staff covers about 85% of the total. Out of 45% of researchers coming from abroad 29% are foreigners coming from more than 50 countries and 16% are returned Italians. The scientific staff currently consists of approximately 60 Principal Investigators110 researchers and technologists350 post-docs and 500 PhD students and grant holders and 130 technicians. External funding has allowed the creation of more than 330 positions . The average age is 34 and the gender balance proportion  is 41% female against 59% male.

In 2015 IIT received 96 million euros in public funding (accounting for 80% of its budget) and obtained 22 million euros in external funding (accounting for 20% of its budget). External funding comes from 18 European Projects, other 17 national and international competitive projects and approximately 60 industrial projects.

So far IIT accounts for: about 6990 publications, more than 130 European grants and 11 ERC grants, more than 350 patents or patent applications12 up start-ups and as many  which are about to be launched. The Institute’s scientific activity has been further strengthened since 2009 with the establishment of 11 research nodes throughout Italy (Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) and abroad (MIT and Harvard University, USA), which, along with the Genoa-based Central Lab, implement the research programs included in the 2015-2017 Strategic Plan.