Dr. Roberto Palomba is a Post Doc in the Nanotechnology for Precision Medicine Laboratory at IIT-Istituto Italiano di Tecnologia, since December 2015. He is currently an AIRC fellows working with Prof. Paolo Decuzzi on the development of novel therapeutic strategies for triple negative breast cancer. His research activity focuses on investigating how geometrical and mechanical features of nanoconstructs modulates phagocytic cell behaviors. On top of this, his work aims to investigate the biodistribution of Discoidal Polimeric Nanocarriers (DPNs) and their ability to escape the reticuloendothelial organs in preclinical models of breast cancer. In this regard, he is recently also developing microfluidic-based liver sinusoid models.
Dr Palomba achieved his MSc in Medical Biotechnology at the University of Naples Federico II in October 2008, he studied the molecular pathogenesis of acute lymphoblastic leukemia. During his PhD in Biotechnology, his activities focused on the identification of Aldolse C protein interactors in mammalian brain, the gene regulation of brain-specific human aldolase C and the process of differentiation of myoblasts. During these years, he supervised and coordinated the activities of several MSc students.
In July 2014, he moved to USA and started a Post Doc at the “Houston Methodist Research Institute”. His studies were aimed to the development of a drug carrier capable to target tumor vasculature and increase its permeability. As main side projects, he investigated the margination of microparticles in blood vessels, new strategies aimed to increase nanoparticles diffusion in tumor microenvironment the ex vivo engineering of breast cancer niche.