Denis Garoli, born in Padova, get a master Degree in Physics in the 2003 at Padova University. In the 2008 awarded the PhD in Space Science and Technology with a thesis on the development of innovative technologies for the environmental conservation. In 2011 he get Degree in Biotechnology.During the last 5 years he moved from Laboratory for Nanofabrication of Nanodevices (LaNN -Venetonanotech) in Padova where he was senior scientist in charge with Clean Room facilities for nanofabrication. From 2014 up to now, he’s working as researcher at Istituto Italiano di Tecnologia (IIT) on the several research fields such as: plasmonics, biosensing, single-molecule detection and manipulation.In 2015 he won an Horizon 2020 FET project ProseqO (co-ordinator – rank #1 among more than 880 proposals): PROtein SEQuencing using Optical single molecule real-time detection.Within this project he also started a continuous collaboration with the Biotech company AbAnalitica in Padova where he supports the R&D activities.The main results of the research during these years regard the design, fabrication and test of innovative plasmonic devices for several applications, from biosensing to optical beam manipulation. During the last two years he’s mainly focused on nanopore technology for single molecule detection.
Horizon 2020 FET Open ProseqO - Coordinator
The project regards the development of new technologies for single molecule detection and manipulationwith the final goal of DNA/RNA and protein sequencing. In particular, the advent of analytical techniques withextremely low limits of detection has led to dramatic progresses in the field of nucleic acids sequencing. Despitethe development of next generation sequencing platforms, the current genome sequencing task remains formidable, and revolutionary advances in DNA sequencing technology are still demanded. Another technological revolution would be a fast and reliable sequencing of proteins, which are the primary actors invirtually all life processes and are coded by DNA sequences known as genes.
List of recent publications:
G. C. Messina, X. Zambrana-Puyalto, C. A. Gonano, N. Maccaferri, D. Garoli, F. De Angelis, "Controlled two-state switchable thermoplasmonic tweezers for dynamic manipulation of nano-objects based on vertical gold nanochannels.", Submitted to ACS Nano (2019).