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Leonardo De Mattos

Team Leader - Permanent Researcher
Technologist
Advanced Robotics
Leonardo De Mattos
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Biografia

Leonardo Serra De Mattos (B.Sc. 1998, M.Sc. 2003, Ph.D. 2007) is a Permanent Researcher and Head of the Biomedical Robotics Laboratory at the Italian Institute of Technology (IIT, Genoa). His research background includes medical robotics, robot-assisted surgery, laser microsurgery, smart medical devices, computer vision, medical image analysis, user interfaces, mixed and augmented reality, biomedical sensors, systems integration, automation, usability analysis, and robotic micro-biomanipulation. Leonardo received his Ph.D. degree in electrical engineering from the North Carolina State University (NCSU, USA), where he worked as research assistant at the Center for Robotics and Intelligent Machines (CRIM) from 2002 until 2007. Since then he has been a researcher at the IIT’s Department of Advanced Robotics.

Dr. De Mattos is currently leading a team of 14 researchers and technicians at IIT and collaborates closely with other institutions, including hospitals and industry. So far, he has been a key player in securing over 20 million Euros for research through externally funded projects. He was the PI and coordinator of the European project µRALP – Micro-Technologies and Systems for Robot-Assisted Laser Phonomicrosurgery, and of the TEEP-SLA project, which was dedicated to the creation of new interfaces and assistive systems for ALS patients. Currently, Leonardo is the PI and coordinator of the European project AIRCARE and of the translational project Robotic Microsurgery. He is also leading the work on robotic devices for intravenous access, pediatric neurosurgery and surgical augmented reality.

Dr. De Mattos has graduated 20 PhD students and is currently supervising another 4 PhD candidates. He is the author or co-author of more than 200 peer-reviewed publications and 9 patents, and has been the chair and main organizer of several international scientific events, including both the 4th and 9th Joint Workshop on New Technologies for Computer/Robot Assisted Surgery (CRAS 2014, CRAS 2019), the IEEE BioRob 2014 Workshop on Robotic Microsurgery and Image-Guided Surgical Interventions, and the IEEE BioRob 2012 Workshop on Robot-Assisted Laryngeal Microsurgery. He is currently serving as Editor for Applied Sciences and IEEE IROS, and as Associated Editor for IEEE Robotics and Automation Letters. Recently, he has served as Guest Editor for IEEE Transactions on Robotics and Bionics, Frontiers in Robotics and AI, Journal of Intelligent & Robotic Systems, Journal of Medical Robotics Research, and for several IEEE flagship conferences.

All Publications
2026
Mariano F., De Momi E., Berselli G., Jovanova J., Mattos L.S.
A dual-joint compliant architecture for precision control in robotic neuroendoscopy
Precision Engineering, vol. 99, pp. 632-642
Article Journal
2026
De Alexandria A.R., Penza V., Neri A., De Mattos L.S.
Advances in Urological Surgery: The 3D Modeling Revolution
IEEE Access, vol. 14, pp. 67341-67361
Review Journal
2026
Koskinopoulou M., Acemoglu A., Civati L., Mattos L.S.
Cathbot-Pro: A Handheld Robotic Device for Vision-Guided Peripheral Intravenous Catheterization Using NIR Imaging
IEEE Transactions on Medical Robotics and Bionics
Article Journal
2026
Baldini C., Kushibar K., Osuala R., Balocco S., Diaz O., Lekadir K., Mattos L.S.
Clinically-Guided Data Synthesis for Laryngeal Lesion Detection
Lecture Notes in Computer Science, vol. 15970 LNCS, pp. 54-63
2026
De Luca D., Federici L., Fiorentino M.C., Sampieri C., Mora F., Peretti G., Bellini E., Sakellaridis A.C., Razou A., Kotsis G.P., De Mattos L.S., Moccia S.
Dual-branch semi-supervised patch learning for laryngeal squamous cell carcinoma detection in endoscopic images
Biomedical Signal Processing and Control, vol. 126
Article Journal
Awards and Achievements
2023
Neri A., Penza V., Mattos L.S.
BEST POSTER AWARD for “Comparative Study of Interfaces for Surgical Augmented Reality”
2023
Cheng Z., Mattos L.S.
BEST RESEARCH PAPER RUNNER-UP for “A Novel Intraoperative Force Estimation Method via Electrical Bioimpedance Sensing”
2022
Azam M. A., Sampieri C., Ioppi A., Benzi P., Giordano G., De Vecchi M., Campagnari V., Li S., Guastini L., Paderno A., Moccia S., Piazza C., Mattos L. S., Peretti G.
FIRST PRIZE, “Videomics of the upper aero-digestive tract,” National Congress of the Italian Society of Otorhinolaryngology, SIO 2022, 27 May 2022
2020
Mattos L., Acemoglu A., Caldwell D.
BEST CONFERENCE PAPER AWARD: "5G Telesurgery – Feasibility Experiment and First Public Demo"
2020
Mattos L. S., Acemoglu A.
BEST CONFERENCE PAPER AWARD, “5G Telesurgery – Feasibility Experiment and First Public Demo”, CRAS 2020, September 2020