I am interested in how neural circuits encode environmental cues to produce behavioral responses. I use the nematode C. elegans as a model organism to study neural network dynamics and brain functioning. Keywords of my activity are neural networks, connectivity, whole-brain activity, and sensory stimulation. My research takes advantage from the complementary use of numerical, theoretical, and experimental approaches in an interdisciplinary framework based on calcium imaging microscopy and behavioral recordings, microfluidics, molecular biology, transcriptomics, and novel whole-brain and single-neuron modeling.
Research center
CLN²S@Sapienza
Biografia
Education
Title: PhD in physics, "Nonlinear Optics and Laser Emission through Random Media"
Institute: "Sapienza" University of Rome
Location: Rome
Country: Italy
From: 2008 To: 2011
All Publications
2022
Di Rienzo L., De Flaviis L., Ruocco G., Folli V., Milanetti E.
Binding site identification of G protein-coupled receptors through a 3D Zernike polynomials-based method: application to C. elegans olfactory receptors
Journal of Computer-Aided Molecular Design, vol. 36, (no. 1), pp. 11-24
2022
Di Rocco M., Galosi S., Lanza E., Tosato F., Caprini D., Folli V., Friedman J., Bocchinfuso G., Martire A., Di Schiavi E., Leuzzi V., Martinelli S.
Caenorhabditis elegans provides an efficient drug screening platform for GNAO1-related disorders and highlights the potential role of caffeine in controlling dyskinesia
Human Molecular Genetics, vol. 31, (no. 6), pp. 929-941
2021
Lanza E., Di Angelantonio S., Gosti G., Ruocco G., Folli V.
A recurrent neural network model of C. elegans responses to aversive stimuli
Neurocomputing, vol. 430, pp. 1-13
2021
Caprini D., Schwartz S., Lanza E., Milanetti E., Lucente V., Ferrarese G., Chiodo L., Nicoletti M., Folli V.
A Shearless Microfluidic Device Detects a Role in Mechanosensitivity for AWCON Neuron in Caenorhabditis elegans
Advanced Biology, vol. 5, (no. 9)
2021
Lanza E., Rocco M.D., Schwartz S., Caprini D., Milanetti E., Ferrarese G., Lonardo M.T., Pannone L., Ruocco G., Martinelli S., Folli V.
C. elegans-based chemosensation strategy for the early detection of cancer metabolites in urine samples
Scientific Reports, vol. 11, (no. 1)
Colleagues of Nanotechnologies for Neurosciences
