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Sine Mandrup Bertozzi

Analytical Chemistry Facility
Chief Technician
Analytical Chemistry
Sine Mandrup Bertozzi
Phone
Research center
Biografia

I hold a Master Degree in Chemical Engineering (2000) from the Department of Organic Chemistry at the Technical University of Denmark - DTU (Denmark). I have a background in the pharmaceutical industry, where I have been working as a synthetic organic/medicinal chemist in Early Drug Discovery at Novartis Pharma (Switzerland) and ACADIA Pharmaceuticals (Denmark), and also in R&D at PolyPeptide Laboratories (Denmark). In 2005, I embarked on a career in the analytical chemistry field providing support to the medicinal chemistry in early drug discovery projects at ACADIA Pharmaceuticals (Sweden). In 2010, I joined IIT as a Senior Technician in the Drug Discovery and Development (D3) Department, where I have been part of setting up the analytical chemistry and biochemistry lab. Within the Analytical Chemistry Facility, I am responsible for in vitro DMPK profiling, chemical characterization and purification of compounds for research projects within IIT and external collaborations. I have co-authored 33 publications in peer-reviewed journals.


Education

Title: M.Sc. in Chemical Engineering
Institute: Technical University of Denmark (DTU)
Location: Kgs. Lyngby
Country: Denmark
From: 1993 To: 2000

All Publications
2025
Vuong L.M., Hachey S., Shiu J., Xie D.F., Salvador N., Brindani N., Bertozzi S.M., Summa M., Bertorelli R., Armirotti A., Pham R., Ku V.S.H., Limbekar S.D., Nguyen T., Choi B., Hughes C.C.W., De Vivo M., Ganesan A.K.
CDC42-effector interaction inhibitors alter patterns of vessel arborization in skin and tumors in vivo
iScience, vol. 28, (no. 7)
Article Journal
2025
Montani C., Iovino L., Di Vetta F., Pasquin Mariani J. C. R., De Guzman A. E., Gini S., Galbusera A., DEpifanio B., Ghirardini E., Cornuti S., Dadà L., Putignano E., Alessandrì M. G., Vasirani G., Bertozzi S. M., Armirotti A., Baroncelli L., Gozzi A.
Connectomic and behavioural alterations in creatine transporter deficiency are partially normalized by gene therapy
Brain
Article Journal
2025
Economou C.N., Bertozzi S.M., Nardi M., Paul U.C., Fiorentini F., Ferrari G., Contardi M., Armirotti A., Fragouli D., Athanassiou A.
Enhanced biodegradation of polylactic acid by Aspergillus oryzae lipase: Toward sustainable plastic end-of-life solutions
Bioresource Technology, vol. 434
2025
Economou C. N., Bertozzi S. M., Nardi M., Paul U., Fiorentini F., Ferrari G., Contardi M., Armirotti A., Fragouli D., Athanassiou A.
Enzymatic degradation of polylactic acid films and microparticles with lipase enzyme from Aspergillus oryzae
8th International Conference on Multifunctional, Hybrid and Nanomaterials, 3-6 March 2025, Montpellier, France
Conference Paper Conference
2025
Squarzoni A., Boschetti G., Bertozzi S.M., Summa M., Serani A., Milandri E., Mandrioli R., Protti M., Mercolini L., Montani C., Capodivento G., Cangemi G., Pedemonte N., Bandiera T., Benfenati F., Nobbio L., Bertorelli R., Armirotti A.
Exposure of dams to Elexacaftor/ Tezacaftor/Ivacaftor during pregnancy and breastfeeding induces reversible alterations in newborn wild type CD-1 mice
Journal of Cystic Fibrosis
Article Journal