Research center
CHT@Erzelli
About
All Publications
2023
Brindani N., Vuong L.M., Acquistapace I.M., La Serra M.A., Ortega J.A., Veronesi M., Bertozzi S.M., Summa M., Girotto S., Bertorelli R., Armirotti A., Ganesan A.K., De Vivo M.
Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer
Journal of Medicinal Chemistry, vol. 66, (no. 8), pp. 5981-6001
Article
Journal
2022
La Serra M. A., Vidossich P., Acquistapace I. M., Ganesan A. K., De Vivo M.
Alchemical Free Energy Calculations to Investigate Protein–Protein Interactions: the Case of the CDC42/PAK1 Complex
Journal of Chemical Information and Modeling
Article
Journal
2022
Acquistapace I.M., Thompson E. J., Kühn I., Bedford M. R., Brearley C. A., Hemmings A. M.
Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA
International Journal of Molecular Sciences
2022
Jahid S., Ortega J.A., Vuong L.M., Acquistapace I.M., Hachey S.J., Flesher J.L., La Serra M.A., Brindani N., La Sala G., Manigrasso J., Arencibia J.M., Bertozzi S.M., Summa M., Bertorelli R., Armirotti A., Jin R., Liu Z., Chen C.-F., Edwards R., Hughes C.C.W., De Vivo M., Ganesan A.K.
Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer
Cell Reports, vol. 39, (no. 1)
2020
Acquistapace I. M., Zietek M. A., Li A. W. H., Salmon M., Kühn I., Bedford M. R., Brearley C. A., Hemmings A. M.
Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced-fit structural mechanism
Journal of Biological Chemistry, vol. 295, (no. 51), pp. 17724–17737
Colleagues of Molecular Modeling and Drug Discovery