Ambra Gianotti
Research Organization Directorate, Tenure Track Office
Research center
CCT@Morego
All Publications
2022
Ghigo A., Murabito A., Sala V., Pisano A.R., Bertolini S., Gianotti A., Caci E., Montresor A., Premchandar A., Pirozzi F., Ren K., Sala A.D., Mergiotti M., Richter W., de Poel E., Matthey M., Caldrer S., Cardone R.A., Civiletti F., Costamagna A., Quinney N.L., Butnarasu C., Visentin S., Ruggiero M.R., Baroni S., Crich S.G., Ramel D., Laffargue M., Tocchetti C.G., Levi R., Conti M., Lu X.-Y., Melotti P., Sorio C., De Rose V., Facchinetti F., Fanelli V., Wenzel D., Fleischmann B.K., Mall M.A., Beekman J., Laudanna C., Gentzsch M., Lukacs G.L., Pedemonte N., Hirsch E.
A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases
Science Translational Medicine, vol. 14, (no. 638)
2022
Philp A.R., Miranda F., Gianotti A., Mansilla A., Scudieri P., Musante I., Vega G., Figueroa C.D., Galietta L.J.V., Sarmiento J.M., Flores C.A.
KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse model
Physiological Genomics, vol. 54, (no. 7), pp. 273-282
2021
Ferrera L., Capurro V., Delpiano L., Gianotti A., Moran O.
The application of bicarbonate recovers the chemical-physical properties of airway surface liquid in cystic fibrosis epithelia models
Biology, vol. 10, (no. 4)
2020
Pedemonte N., Bertozzi F., Caci E., Sorana F., Fruscia P.D., Tomati V., Ferrera L., Rodriguez-Gimeno A., Berti F., Pesce E., Sondo E., Gianotti A., Scudieri P., Bandiera T., Galietta L.J.V.
Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel
Science advances, vol. 6, (no. 8)
2020
Brindani N., Gianotti A., Giovani S., Giacomina F., Di Fruscia P., Sorana F., Bertozzi S.M., Ottonello G., Goldoni L., Penna I., Russo D., Summa M., Bertorelli R., Ferrera L., Pesce E., Sondo E., Galietta L.J.V., Bandiera T., Pedemonte N., Bertozzi F.
Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1 H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators
Journal of Medicinal Chemistry, vol. 63, (no. 19), pp. 11169-11194
Colleagues of Research Organization Directorate
