The main mission of Computational and Chemical Biology is to develop innovative computational tools and algorithms to enhance the discovery of novel and better medicines. A further strategic asset of our research line is to design, synthesize, and biologically evaluate novel lead candidates for cancer, neurodegenerative diseases, and neglected tropical diseases. The team is composed of a core of computational scientists, who work in strict collaboration with chemists and biologists towards interdisciplinary goals in drug discovery.
Computational and Chemical Biology
Projects
Progetto 5000genomi@VdA, supported by Programma Investimenti per la crescita e l’occupazione 2014/20 (FESR) and Programma Investimenti in favore della crescita e dell’occupazione 2014/20 (FSE) Per maggiori dettagli si veda il sito del Progetto www.5000genomivda.it
The latest publications
2023
Poppi L., Myers S.H., Previtali V., Rinaldi F., Farabegol F., Di Stefano G., Walsh N., Roberti M., Cavalli A.
A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer
EACR
2023
Rocutto L., Maronese M., Traversa F.L., Decherchi S., Cavalli A.
Assessing the Effectiveness of Non-Turing Computing paradigms
IEEE Access
2023
Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A.
Dissecting the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics
EMBO Practical Course Integrative modelling of protein interactions
People
Principal Investigator
Computational and Chemical Biology
- Offerte di lavoro
- Software Developer