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Mattia Pelizzola

Affiliated Researcher
Genomic Science
Research center
About

I am a computational biologist with background in biotechnology and Associate Professor at the Dept. of Biotechnology and Biosciences, Milano-Bicocca University. I lead a research group studying how co- and post- transcriptional events shape gene expression programs. We employ an interdisciplinary approach combining cutting edge experimental and computational methods, including the profiling of nascent and modified RNA, single-molecule Nanopore sequencing, and mathematical modelling (https://www.iit.it/it/web/genomic-science/pelizzola).

Education

Title: PhD in Complexity in Post-Genomic Biology
Institute: University of Torino
Location: Torino
Country: Italy
From: 2004 To: 2006

Title: Master in Bioinformatics
Institute: Milano-Bicocca University
Location: Milano
Country: Italy
From: 2002 To: 2003

Title: Master’s degree in Industrial Biotechnologies
Institute: Milano-Bicocca University
Location: Milano
Country: Italy
From: 1995 To: 2001

Experience External

Title: Postdoctoral Research Associate
Institute: Salk Institute for Biological Science
Location: La Jolla, CA
Country: USA
From: 2009 To: 2011

Title: Postdoctoral Research Associate
Institute: Yale University
Location: New Haven , CT
Country: USA
From: 2007 To: 2009

Top Publications
2017
De Pretis S., Kress T.R., Morelli M.J., Sabo A., Locarno C., Verrecchia A., Doni M., Campaner S., Amati B., Pelizzola M.
Integrative analysis of RNA polymerase II and transcriptional dynamics upon MYC activation
Genome Research, vol. 27, (no. 10), pp. 1658-1664
2014
Sabo A., Kress T.R., Pelizzola M., De Pretis S., Gorski M.M., Tesi A., Morelli M.J., Bora P., Doni M., Verrecchia A., Tonelli C., Faga G., Bianchi V., Ronchi A., Low D., Muller H., Guccione E., Campaner S., Amati B.
Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis
Nature, vol. 511, (no. 7510), pp. 488-492
2011
Lister R., Pelizzola M., Kida Y.S., Hawkins R.D., Nery J.R., Hon G., Antosiewicz-Bourget J., Ogmalley R., Castanon R., Klugman S., Downes M., Yu R., Stewart R., Ren B., Thomson J.A., Evans R.M., Ecker J.R.
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
Nature, vol. 471, (no. 7336), pp. 68-73
2009
Lister R., Pelizzola M., Dowen R.H., Hawkins R.D., Hon G., Tonti-Filippini J., Nery J.R., Lee L., Ye Z., Ngo Q.-M., Edsall L., Antosiewicz-Bourget J., Stewart R., Ruotti V., Millar A.H., Thomson J.A., Ren B., Ecker J.R.
Human DNA methylomes at base resolution show widespread epigenomic differences
Nature, vol. 462, (no. 7271), pp. 315-322
All Publications
2022
Leone M., Galeota E., Masseroli M., Pelizzola M.
Identification, semantic annotation and comparison of combinations of functional elements in multiple biological conditions
Bioinformatics, vol. 38, (no. 5), pp. 1183-1190
2021
Lepesant J.M.J., Iampietro C., Galeota E., Auge B., Aguirrenbengoa M., Merce C., Chaubet C., Rocher V., Haenlin M., Waltzer L., Pelizzola M., Di Stefano L.
A dual role of dLsd1 in oogenesis: Regulating developmental genes and repressing transposons
Nucleic Acids Research, vol. 48, (no. 3), pp. 1206-1224
2021
Furlan M., Delgado-Tejedor A., Mulroney L., Pelizzola M., Novoa E.M., Leonardi T.
Computational methods for RNA modification detection from nanopore direct RNA sequencing data
RNA Biology, vol. 18, (no. S1), pp. 31-40
2021
Furlan M., de Pretis S., Pelizzola M.
Dynamics of transcriptional and post-transcriptional regulation
Briefings in Bioinformatics, vol. 22, (no. 4)
2021
de Pretis S., Furlan M., Pelizzola M.
Identification of Genes Post-Transcriptionally Regulated from RNA-seq: The Case Study of Liver Hepatocellular Carcinoma
Methods in molecular biology (Clifton, N.J.), vol. 2284, pp. 271-287
Book Chapter Book Series