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Valentina Di Francesco

Post Doc - Fellow
Nanotechnology for Precision Medicine
Research center

Valentina Di Francesco is a PhD Student in “Bioengineering and Robotics” at the university of Genoa. She is carrying out the doctoral activities at the laboratory of the Nanotechnology for Precision Medicine of Professor Paolo Decuzzi at Istituto Italiano di Tecnologia, since November 2017. Her research activities have focused on the design, preparation, physicochemical characterization, in vitro and in vivo evaluation of Supramolecular Nanotherapeutics for systemic delivery of bioactive compounds for cardiovascular disease, in particular Atherosclerosis.

She achieved her MSc Degree in Chemistry and Pharmacology Technology in at the “G. d’Annunzio” University of Chieti – Pescara in March 2016, with a thesis on "Therapeutic non phospholipid vesicles for neuronal anticancer treatment" under the supervision of Prof. Luisa Di Marzio (University of Chieti-Pescara “G.d’Annunzio”).

All Publications
Di Francesco V., Di Francesco M., Decuzzi P., Palomba R., Ferreira M.
Synthesis of two methotrexate prodrugs for optimizing drug loading into liposomes
Pharmaceutics, vol. 13, (no. 3), pp. 1-16
Di Francesco M., Primavera R., Summa M., Pannuzzo M., Di Francesco V., Di Mascolo D., Bertorelli R., Decuzzi P.
Engineering shape-defined PLGA microPlates for the sustained release of anti-inflammatory molecules
Journal of Controlled Release, vol. 319, pp. 201-212
Article Journal
Di Francesco V., Gurgone D., Palomba R., Ferreira M.F.M.M., Catelani T., Cervadoro A., Maffia P., Decuzzi P.
Modulating Lipoprotein Transcellular Transport and Atherosclerotic Plaque Formation in ApoE-/-Mice via Nanoformulated Lipid-Methotrexate Conjugates
ACS Applied Materials and Interfaces, vol. 12, (no. 34), pp. 37943-37956
Ferreira M., Rizzuti I.F., Palange A.L., Barbato M.G., Di Francesco V., Di Francesco M., Decuzzi P.
Optimizing the Pharmacological Properties of Discoidal Polymeric Nanoconstructs Against Triple-Negative Breast Cancer Cells
Frontiers in Bioengineering and Biotechnology, vol. 8