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Davide De Pietri Tonelli

Senior Researcher Tenured - Principal Investigator
Neurobiology of miRNA
Phone
Research center
About

We aim at dissecting the molecular control of Neural Stem Cell (NSC) fate in mammalian neurogenesis by focusing on noncoding RNAs and other post-transcriprional mechanisms, as key to understand/cure brain (mal)formation, aging and tumours. Current Research in my group focuses on:i) Small RNAs in basic and translational aspects of neurogenesis in mammals. ii) New technological approaches enabling oligotherapy for human brain dysfunctions

Experience External

Title: Contract Professor of “Developmental Neurobiology” for the Master degree in biotechnology
Institute: Università di Genova
Location: Genoa
Country: italy
From: 2018 To: null

Title: Contract Professor of “Neural stem cell differentiation” for the Master degree in Molecular and Cell Biology
Institute: Università di Genova
Location: Genoa
Country: italy
From: 2008 To: 2010

Title: External collaborator
Institute: Clontech inc. (Mountain View, CA, USA).
Location: Mountain View (CA)
Country: USA
From: 2006 To: 2006

Title: Researcher
Institute: Max-Planck Institute of Molecular Cell-Biology and Genetics
Location: Dresden
Country: Germany
From: 2004 To: 2008

Title: Fellow
Institute: DIBIT-San Raffaele Reserch Institute
Location: Milan
Country: Italy
From: 1999 To: 2003

Top Publications
2019
Pons-Espinal M., Gasperini C., Marzi M.J., Braccia C., Armirotti A., Potzsch A., Walker T.L., Fabel K., Nicassio F., Kempermann G., De Pietri Tonelli D.
MiR-135a-5p Is Critical for Exercise-Induced Adult Neurogenesis
Stem Cell Reports, vol. 12, (no. 6), pp. 1298-1312
2017
Barca-Mayo O., Pons-Espinal M., Follert P., Armirotti A., Berdondini L., De Pietri Tonelli D.
Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling
Nature Communications, vol. 8
2017
De Pietri Tonelli D.
Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain
Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain, pp. 1-316, Publisher: Elsevier Inc.
Book Book
2017
Marinaro F., Marzi M.J., Hoffmann N., Amin H., Pelizzoli R., Niola F., Nicassio F., De Pietri Tonelli D.
MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression
EMBO Reports, vol. 18, (no. 4), pp. 603-618
2017
Pons-Espinal M., de Luca E., Marzi M.J., Beckervordersandforth R., Armirotti A., Nicassio F., Fabel K., Kempermann G., De Pietri Tonelli D.
Synergic Functions of miRNAs Determine Neuronal Fate of Adult Neural Stem Cells
Stem Cell Reports, vol. 8, (no. 4), pp. 1046-1061
All Publications
2024
Pezzilli S., Ferranti F., Perilli S., Tuntevski K., Cialdai F., Giantomasi L., Di Fino L., Negri B., Masotti A., De Pietri Tonelli D., Monici M.
AstRNAuts and NUT: using commercial flight opportunities to study the response of the human organism to the space environment
COSPAR 2024 45th Scientific Assembly
Poster Conference
2024
Tuntevski K., Beatini S., Giantomasi L., Gasperini C., Pelizzoli R., Cossu R.M., Sanges R., Gustincich S., De Pietri Tonelli D.
Dissecting the Mechanism of piRNA Biogenesis and Function in Adult Somatic Stem Cells of the Murine Hippocampal Niche
5th International Conference on the Long and the Short of Non-Coding RNAs (06/17/2024 - 06/22/2024; Chania, Crete, Greece)
Poster Conference
2024
Giantomasi L., Beatini S., Tuntevski K., Pelizzoli R., Sanges R., De Pietri Tonelli D.
Exploring the role of the piRNA pathway in microglia and neuroinflammation
5th International Conference on the Long and the Short of Non-Coding RNAs
Poster Conference
2024
Comas M., De Pietri Tonelli D., Berdondini L., Astiz M.
Ontogeny of the circadian system: a multiscale process throughout development
Trends in Neurosciences, vol. 47, (no. 1), pp. 36-46
2023
Giantomasi L., Ribeiro J.F., Barca-Mayo O., Malerba M., Miele E., De Pietri Tonelli D., Berdondini L.
Astrocytes actively support long-range molecular clock synchronization of segregated neuronal populations
Scientific Reports, vol. 13, (no. 1)
Article Journal
Organized Events
2022
De Pietri Tonelli D., Nicassio F., Tartaglia GG.
Co-coordinator of the “RNA Collaborative Seminar Series” by the RNA society (USA)
2022
Prochiantz A., De Pietri Tonelli D., Gustincich S.
Co-organizer of the 1st IIT-Collège de France Joint Neuroscience Meeting
2017
De Pietri Tonelli D.
Co-organiser of the symposium: "Emerging complexity and functions of miRNAs-dependent regulation in neuroscience"
2014
De Pietri Tonelli D.
Co-organiser of the Symposium "microRNAs in brain development ad function"
2012
De Pietri Tonelli D.
Chairman and Lecturer at the Symposium "MicroRNAs in Development"