Our aim is to uncover the mechanisms underlying cognitive and social alterations relevant to psychiatric and neurodevelopmental disorders with the final goal of developing biologically-based and personalized therapeutic strategies. We employ cross-disciplinary approaches including detailed in vivo studies in genetically modified mice strictly combined with clinical investigations.

• To implement more efficient and biologically-supported personalized medicine for cognitive and social alterations relevant to psychiatric and neurodevelopmental disorders.
• To develop a bidirectional mouse-human approach to accelerate the development of precision medicine strategies, with a deeper understanding of the biological mechanisms involved.
• To investigate genetics, circuits, and cell-type specific mechanisms underlying higher-order cognitive and social processes.
• To understand the brain-immune system interplay in modulating cognitive and social functions, their developmental trajectories, and the impact of early treatments.

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