18 publications found

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  • 2017
    *Barca-Mayo O.iit , Pons-Espinal M.iit , Follert P.iit , Armirotti A.iit , Berdondini L.iit , *De Pietri Tonelli D.iit

    Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling

    Nature Communications, vol. 8
    Article
  • 2017
    *Amin H.iit , Marinaro F.iit , De Pietri Tonelli D.iit , Berdondini L.iit

    Developmental excitatory-toinhibitory GABA-polarity switch is disrupted in 22q11.2 deletion syndrome: a potential target for clinical therapeutics

    Scientific Reports, vol. 7, (no. 15752)
    Article
  • 2017
    *De Pietri Tonelli D.iit

    Essentials of Noncoding RNA in Neuroscience 1st Edition Ontogenetics, Plasticity of the Vertebrate Brain

    Essentials of Noncoding RNA in Neuroscience 1st Edition Ontogenetics, Plasticity of the Vertebrate Brain, Publisher: Elsevier
    Book
  • 2017
    *De Pietri Tonelli D.iit

    Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain

    Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain, pp. 1-316, Publisher: Elsevier Inc.
    Book
  • 2017
    Marinaro F.iit , Pons-Espinal M.iit , *De Pietri Tonelli D.iit

    Methodological Challenges in Functional Investigation and Therapeutic Use of microRNAs

    Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain, pp. 61-79, Publisher: Elsevier Inc.
    Book Chapter
  • 2017
    Marinaro F. , Pons Espinal M. , *De Pietri Tonelli D.iit

    Methodological challenges in functional investigation and therapeutic use of miRNAs

    Essentials of Noncoding RNA in Neuroscience 1st Edition Ontogenetics, Plasticity of the Vertebrate Brain, Publisher: Elsevier
    Book Chapter
  • 2017
    Marinaro F.iit , Marzi M.J.iit , Hoffmann N.iit , Amin H.iit , *Pelizzoli R.iit , Niola F.iit , Nicassio F.iit , *De Pietri Tonelli D.iit

    MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression

    EMBO Reports, vol. 18, (no. 4), pp. 603-618
    Article
  • 2017
    *De Pietri Tonelli D.iit

    Preface

    Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain, pp. xvii-xx, Publisher: Elsevier Inc.
    Editorial
  • 2017
    Pons-Espinal M.iit , de Luca E.iit , Marzi M.J. , Beckervordersandforth R. , Armirotti A.iit , Nicassio F. , Fabel K. , Kempermann G. , *De Pietri Tonelli D.iit

    Synergic Functions of miRNAs Determine Neuronal Fate of Adult Neural Stem Cells

    Stem Cell Reports, vol. 8, (no. 4), pp. 1046-1061
    Article
  • 2014
    Barca-Mayo O.iit , *De Pietri Tonelli D.iit

    Convergent microRNA actions coordinate neocortical development

    Cellular and Molecular Life Sciences, vol. 71, (no. 16), pp. 2975-2995
    Review
  • 2014
    De Pietri Tonelli D.iit , Clovis Y.M.iit , Huttner W.B.

    Detection and monitoring of microRNA expression in developing mouse brain and fixed brain cryosections

    Methods in molecular biology (Clifton, N.J.), vol. 1092, pp. 31-42
    Article
  • 2013
    Petrelli A.iit , Marconi E.iit , Salerno M.iit , De Pietri Tonelli D.iit , *Berdondini L.iit , *Dante S.iit

    Nano-volume drop patterning for rapid on-chip neuronal connect-ability assays

    Lab on a Chip - Miniaturisation for Chemistry and Biology, vol. 13, (no. 22), pp. 4419-4429
    Article
  • 2012
    Clovis Y.M.iit , Enard W. , Marinaro F.iit , Huttner W.B. , *de Pietri Tonelli D.iit

    Convergent repression of Foxp2 3 ́UTR by miR-9 and miR-132 in embryonic mouse neocortex: Implications for radial migration of neurons

    Development (Cambridge), vol. 139, (no. 18), pp. 3332-3342
    Article
  • 2012
    Nigro A. , Menon R. , Bergamaschi A. , Clovis Y.M.iit , Baldi A. , Ehrmann M. , Comi G. , De Pietri Tonelli D.iit , Farina C. , Martino G. , *Muzio L.

    MiR-30e and miR-181d control Radial Glia cell proliferation via HtrA1 modulation

    Cell Death and Disease, vol. 3, (no. 8)
    Article
  • 2011
    *Candiani S. , *Moronti L. , *De Pietri Tonelli D.iit , *Garbarino G. , *Pestarino M.

    A study of neural-related microRNAs in the developing amphioxus

    EvoDevo, vol. 2, (no. 1)
    Article
  • 2010
    Klempin F. , Babu H. , De Pietri Tonelli D.iit , Alarcon E. , Fabel K. , *Kempermann G.

    Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis

    Frontiers in Molecular Neuroscience, vol. 3, (no. JUL)
    Article
  • 2008
    *De Pietri Tonelli D.iit , Pulvers J.N. , Haffner C. , Murchison E.P. , Hannon G.J. , *Huttner W.B.

    miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex

    Development (Cambridge), vol. 135, (no. 23), pp. 3911-3921
    Article
  • 2008
    *Pelizzoli R.iit , Tacchetti C. , Luzzi P. , Strangio A. , Bellese G. , Zappia E. , *Guazzi S.

    TTF-1/NKX2.1 up-regulates the in vivo transcription of nestin

    International Journal of Developmental Biology, vol. 52, (no. 1), pp. 55-62
    Article

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I numeri di IIT

L’Istituto Italiano di Tecnologia (IIT) è una fondazione di diritto privato - cfr. determinazione Corte dei Conti 23/2015 “IIT è una fondazione da inquadrare fra gli organismi di diritto pubblico con la scelta di un modello di organizzazione di diritto privato per rispondere all’esigenza di assicurare procedure più snelle nella selezione non solo nell’ambito nazionale dei collaboratori, scienziati e ricercatori ”.

IIT è sotto la vigilanza del Ministero dell'Istruzione, dell'Università e della Ricerca e del Ministero dell'Economia e delle Finanze ed è stato istituito con la Legge 326/2003. La Fondazione ha l'obiettivo di promuovere l'eccellenza nella ricerca di base e in quella applicata e di favorire lo sviluppo del sistema economico nazionale. La costruzione dei laboratori iniziata nel 2006 si è conclusa nel 2009.

Lo staff complessivo di IIT conta circa 1440 persone. L’area scientifica è rappresentata da circa l’85% del personale. Il 45% dei ricercatori proviene dall’estero: di questi, il 29% è costituito da stranieri provenienti da oltre 50 Paesi e il 16% da italiani rientrati. Oggi il personale scientifico è composto da circa 60 principal investigators, circa 110 ricercatori e tecnologi di staff, circa 350 post doc, circa 500 studenti di dottorato e borsisti, circa 130 tecnici. Oltre 330 posti su 1400 creati su fondi esterni. Età media 34 anni. 41% donne / 59 % uomini.

Nel 2015 IIT ha ricevuto finanziamenti pubblici per circa 96 milioni di euro (80% del budget), conseguendo fondi esterni per 22 milioni di euro (20% budget) provenienti da 18 progetti europei17 finanziamenti da istituzioni nazionali e internazionali, circa 60 progetti industriali

La produzione di IIT ad oggi vanta circa 6990 pubblicazioni, oltre 130 finanziamenti Europei e 11 ERC, più di 350 domande di brevetto attive, oltre 12 start up costituite e altrettante in fase di lancio. Dal 2009 l’attività scientifica è stata ulteriormente rafforzata con la creazione di dieci centri di ricerca nel territorio nazionale (a Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) e internazionale (MIT ed Harvard negli USA) che, unitamente al Laboratorio Centrale di Genova, sviluppano i programmi di ricerca del piano scientifico 2015-2017.

IIT: the numbers

Istituto Italiano di Tecnologia (IIT) is a public research institute that adopts the organizational model of a private law foundation. IIT is overseen by Ministero dell'Istruzione, dell'Università e della Ricerca and Ministero dell'Economia e delle Finanze (the Italian Ministries of Education, Economy and Finance).  The Institute was set up according to Italian law 326/2003 with the objective of promoting excellence in basic and applied research andfostering Italy’s economic development. Construction of the Laboratories started in 2006 and finished in 2009.

IIT has an overall staff of about 1,440 people. The scientific staff covers about 85% of the total. Out of 45% of researchers coming from abroad 29% are foreigners coming from more than 50 countries and 16% are returned Italians. The scientific staff currently consists of approximately 60 Principal Investigators110 researchers and technologists350 post-docs and 500 PhD students and grant holders and 130 technicians. External funding has allowed the creation of more than 330 positions . The average age is 34 and the gender balance proportion  is 41% female against 59% male.

In 2015 IIT received 96 million euros in public funding (accounting for 80% of its budget) and obtained 22 million euros in external funding (accounting for 20% of its budget). External funding comes from 18 European Projects, other 17 national and international competitive projects and approximately 60 industrial projects.

So far IIT accounts for: about 6990 publications, more than 130 European grants and 11 ERC grants, more than 350 patents or patent applications12 up start-ups and as many  which are about to be launched. The Institute’s scientific activity has been further strengthened since 2009 with the establishment of 11 research nodes throughout Italy (Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) and abroad (MIT and Harvard University, USA), which, along with the Genoa-based Central Lab, implement the research programs included in the 2015-2017 Strategic Plan.