202 publications found

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  • 2020
    Musio B. , Ragone R. , Todisco S. , Rizzuti A. , Latronico M. , Mastrorilli P. , Pontrelli S. , Intini N. , Scapicchio P. , Triggiani M. , Di Noia T. , Acquotti D. , Airoldi C. , Assfalg M. , Barge A. , Bateman L. , Benevelli F. , Bertelli D. , Bertocchi F. , Bieliauskas A. , Borioni A. , Caligiani A. , Callone E. , Camra A. , Cesare Marincola F. , Chalasani D. , Consonni R. , Dambruoso P. , Davalli S. , David T. , Diehl B. , Donarski J. , Gil A.M. , Gobetto R. , Goldoni L.iit , Hamon E. , Harwood J.S. , Kobrlova A. , Longobardi F. , Luisi R. , Mallamace D. , Mammi S. , Martin-Biran M. , Mazzei P. , Mele A. , Milone S. , Molero Vilchez D. , Mulder R.J. , Napoli C. , Ragno D. , Randazzo A. , Rossi M.C. , Rotondo A. , Sackus A. , Saez Barajas E. , Schievano E. , Sitaram B. , Stevanato L. , Takis P.G. , Teipel J. , Thomas F. , Torregiani E. , Valensin D. , Veronesi M.iit , Warren J. , Wist J. , Zailer-Hafer E. , Zuccaccia C. , Gallo V.

    A community-built calibration system: The case study of quantification of metabolites in grape juice by qNMR spectroscopy

    Talanta, vol. 214
    Article
  • 2020
    Cristo L.D.iit , Boccuni F. , Iavicoli S. , *Sabella S.iit

    A human-relevant 3d in vitro platform for an effective and rapid simulation of workplace exposure to nanoparticles: Silica nanoparticles as case study

    Nanomaterials, vol. 10, (no. 9), pp. 1-10
    Article
  • 2020
    Cibecchini G. , Veronesi M.iit , Catelani T. , Bandiera T.iit , Guarnieri D. , *Pompa P.P.iit

    Anti-angiogenic effect of graphene oxide in primary human endothelial cells

    ACS applied materials & interfaces
    Article in Press
  • 2020
    Colombo G. , Paladino A. , Woodford M.R. , Backe S.J. , Sager R.A. , Kancherla P. , Daneshvar M.A. , Chen V.Z. , Ahanin E.F. , Bourboulia D. , Prodromou C. , Bergamaschi G. , Strada A. , Cretich M. , Gori A. , Veronesi M.iit , Bandiera T.iit , Vanna R. , Bratslavsky G. , Serapia S. A. , Mollapour M.

    Chemical Perturbation of Oncogenic Protein Folding: from the Prediction of Locally Unstable Structures to the Design of Disruptors of Hsp90-Client Interactions

    Chemistry a European Journal
    Article in Press
  • 2020
    Caputo S.iit , Di Martino S.iit , Cilibrasi V.iit , Tardia P.iit , Mazzonna M.iit , Russo D.iit , Penna I.iit , Summa M.iit , Mandrup Bertozzi S.iit , Realini N.iit , Margaroli N. , Migliore M.iit , Ottonello G.iit , Liu M. , Lansbury P. , Armirotti A.iit , Bertorelli R.iit , Ray S.S. , Skerlj R. , Scarpelli R.iit

    Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors

    Journal of Medicinal Chemistry, vol. 63, (no. 24), pp. 15821-15851
    Article
  • 2020
    Pedemonte N. , Bertozzi F.iit , Caci E. , Sorana F.iit , Fruscia P.D.iit , Tomati V. , Ferrera L. , Rodriguez-Gimeno A.iit , Berti F.iit , Pesce E. , Sondo E. , Gianotti A. , Scudieri P. , Bandiera T.iit , Galietta L.J.V.

    Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel

    Science advances, vol. 6, (no. 8)
    Article
  • 2020
    Liessi N.iit , Pesce E. , Braccia C.iit , Bertozzi S.M.iit , Giraudo A.iit , Bandiera T.iit , Pedemonte N. , *Armirotti A.iit

    Distinctive lipid signatures of bronchial epithelial cells associated with cystic fibrosis drugs, including Trikafta

    JCI insight, vol. 5, (no. 16)
    Article
  • 2020
    Dalvit C. , Veronesi M.iit , Vulpetti A.

    Fluorine NMR functional screening: from purified enzymes to human intact living cells

    Journal of Biomolecular NMR, vol. 74, (no. 10-11), pp. 613-631
    Article
  • 2020
    Linciano P. , Cullia G. , Borsari C. , Santucci M. , Ferrari S. , Witt G. , Gul S. , Kuzikov M. , Ellinger B. , Santarem N. , Cordeiro da Silva A. , Conti P. , Bolognesi M.L. , Roberti M. , Prati F. , Bartoccini F.iit , Retini M. , Piersanti G. , Cavalli A.iit , Goldoni L.iit , Bertozzi S.M.iit , Bertozzi F.iit , Brambilla E.iit , Rizzo V.iit , Piomelli D. , Pinto A. , Bandiera T.iit , Costi M.P.

    Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign

    European Journal of Medicinal Chemistry, vol. 189
    Article
  • 2020
    Brindani N.iit , Gianotti A. , Giovani S.iit , Giacomina F.iit , Di Fruscia P.iit , Sorana F.iit , Bertozzi S.M.iit , Ottonello G.iit , Goldoni L.iit , Penna I.iit , Russo D.iit , Summa M.iit , Bertorelli R.iit , Ferrera L. , Pesce E. , Sondo E. , Galietta L.J.V. , Bandiera T.iit , Pedemonte N. , Bertozzi F.iit

    Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1 H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators

    Journal of Medicinal Chemistry, vol. 63, (no. 19), pp. 11169-11194
    Article
  • 2020
    Blanco M.E. , Barca-Mayo O. , Bandiera T.iit , De Pietri Tonelli D.iit , Armirotti A.

    LC–MS/MS analysis of twelve neurotransmitters and amino acids in mouse cerebrospinal fluid

    Journal of Neuroscience Methods
    Article
  • 2020
    Di Martino S.iit , Tardia P.iit , Cilibrasi V.iit , Caputo S.iit , Mazzonna M.iit , Russo D.iit , Penna I.iit , Realini N.iit , Margaroli N.iit , Migliore M.iit , Pizzirani D.iit , Ottonello G.iit , Bertozzi S.M.iit , Armirotti A.iit , Nguyen D. , Sun Y. , Bongarzone E.R. , Lansbury P. , Liu M. , Skerlj R. , *Scarpelli R.iit

    Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors

    Journal of Medicinal Chemistry, vol. 63, (no. 7), pp. 3634-3664
    Article
  • 2020
    Di Martino R.M.C.iit , Bottegoni G. , Seghetti F. , Russo D.iit , Penna I.iit , De Simone A. , Ottonello G.iit , Mandrup Bertozzi S.iit , Armirotti A.iit , Bandiera T.iit , Belluti F. , Cavalli A.iit

    Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation

    ChemMedChem, vol. 15, (no. 11), pp. 949-954
    Article
  • 2020
    Ursini C. L. , Fresegna A. M. , Ciervo A. , Maiello R. , Del Frate V. , Folesani G. , Galetti M. , Poli D. , Buresti G. , Di Cristo L. , Sabella S.iit , Iavicoli S. , Cavallo D.

    Occupational exposure to graphene and silica nanoparticles. Part II: pilot study to identify a panel of sensitive biomarkers of genotoxic, oxidative and inflammatory effects on suitable biological matrices

    Nanotoxicology
    Article
  • 2020
    Boccuni F. , Ferrante R. , Tombolini F. , Natale C. , Gordiani A. , *Sabella S.iit , Iavicoli S.

    Occupational exposure to graphene and silica nanoparticles. Part I: workplace measurements and samplings

    Nanotoxicology, vol. 14, (no. 9), pp. 1280-1300
    Article
  • 2020
    Rigoldi F. , Donini S.iit , Torretta A.iit , Carbone A.iit , Redaelli A. , Bandiera T.iit , Parisini E.iit , Gautieri A.

    Rational backbone redesign of a fructosyl peptide oxidase to widen its active site access tunnel

    Biotechnology and Bioengineering, vol. 117, (no. 12), pp. 3688-3698
    Article
  • 2020
    Di Cristo L.iit , Grimaldi B.iit , Catelani T.iit , Vazquez E. , Pompa P.P.iit , Sabella S.iit

    Repeated exposure to aerosolized graphene oxide mediates autophagy inhibition and inflammation in a three-dimensional human airway model

    Materials Today Bio, vol. 6
    Article
  • 2020
    Azadniya E. , Goldoni L.iit , Bandiera T.iit , Morlock G.E.

    Same analytical method for both (bio)assay and zone isolation to identify/quantify bioactive compounds by quantitative nuclear magnetic resonance spectroscopy

    Journal of Chromatography A, vol. 1628
    Article
  • 2019
    Bramini M. , Chiacchiaretta M. , Armirotti A. , Rocchi A. , Kale D.D. , Martin Jimenez C. , Vázquez E. , Bandiera T.iit , Ferroni S. , Cesca F.iit , Benfenati F.

    An increase in membrane cholesterol by graphene oxide disrupts calcium homeostasis in primary astrocytes.

    Small
    Article
  • 2019
    Foggetti G. , Ottaggio L. , Russo D.iit , Mazzitelli C. , Monti P. , Degan P. , Miele M. , Fronza G. , Menichini P.

    Autophagy induced by SAHA affects mutant P53 degradation and cancer cell survival

    Bioscience Reports, vol. 39, (no. 2)
    Article

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