Publications And Talks

Publications and Talks

IIT monitors the scientific results ensuing from all of its research lines and groups them in the following sections:

Publications groups IIT scientific publications (books, papers and congresses) since the institute was founded back in 2006. Below you can discover our scientific production.

Scientific Talks gathers talks delivered by our researchers at congresses, workshop and seminars as invited speakers. All scientific talks, filtered by research structure, can be found on a dedicated page.

Dissemination Talks contains all publications and talks that are not strictly scientific, but fundamental to disseminate research results. Explore our dissemination talks.

IIT Publications Search

2020
Pedemonte N., Bertozzi F., Caci E., Sorana F., Fruscia P.D., Tomati V., Ferrera L., Rodriguez-Gimeno A., Berti F., Pesce E., Sondo E., Gianotti A., Scudieri P., Bandiera T., Galietta L.J.V.
Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel
Science advances, vol. 6, (no. 8)
2020
Linciano P., Cullia G., Borsari C., Santucci M., Ferrari S., Witt G., Gul S., Kuzikov M., Ellinger B., Santarem N., Cordeiro da Silva A., Conti P., Bolognesi M.L., Roberti M., Prati F., Bartoccini F., Retini M., Piersanti G., Cavalli A., Goldoni L., Bertozzi S.M., Bertozzi F., Brambilla E., Rizzo V., Piomelli D., Pinto A., Bandiera T., Costi M.P.
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign
European Journal of Medicinal Chemistry, vol. 189
2020
Brindani N., Gianotti A., Giovani S., Giacomina F., Di Fruscia P., Sorana F., Bertozzi S.M., Ottonello G., Goldoni L., Penna I., Russo D., Summa M., Bertorelli R., Ferrera L., Pesce E., Sondo E., Galietta L.J.V., Bandiera T., Pedemonte N., Bertozzi F.
Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1 H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators
Journal of Medicinal Chemistry, vol. 63, (no. 19), pp. 11169-11194
2019
Bertozzi F., Rodríguez-Gimeno A., Berti F., Giraudo A., Bertozzi S.M., Ottonello G., Armirotti A., Caci E., Ferrera L., Tomati V., Sondo E., Pesce E., Pedemonte N., Galietta L.J.V., Bandiera T.
DISCOVERY AND DEVELOPMENT OF A NOVEL NANOMOLAR F508-del CFTR CORRECTOR FOR THE TREATMENT OF CYSTIC FIBROSIS
XXVI National Meeting in Medicinal Chemistry
2018
Ponzano S., Nigrelli G., Fregonese L., Eichler I., Bertozzi F., Bandiera T., Galietta L.J.V., Papaluca M.
A European regulatory perspective on cystic fibrosis: Current treatments, trends in drug development and translational challenges for CFTR modulators
European Respiratory Review, vol. 27, (no. 148)
2018
Bandiera T., Sorana F., Berti F., Rodríguez-Gimeno A., Brindani N., Bertozzi S.M., Ottonello G., Armirotti A., Spanò R., Summa M., Bertorelli R., Penna I., Margaroli N., Russo D., Caci E., Ferrera L., Tomati V., Sondo E., Pesce E., Scudieri P., Bertozzi F., Pedemonte N., Galietta L.J.V.
New correctors rescue f508del-cftr activity at low nanomolar concentrations
European Cystic Fibrosis Society (ECFS) Basic Science Conference
2018
Rodríguez-Gimeno A., Sorana F., Berti F., Brindani N., Bertozzi S.M., Ottonello G., Armirotti A., Spanò R., Summa M., Bertorelli R., Penna I., Margaroli N., Russo D., Caci E., Ferrera L., Tomati V., Sondo E., Pesce E., Scudieri P., Pedemonte N., Galietta L.J.V., Bertozzi F., Bandiera T.
Targeting basic defect in cystic fibrosis: discovery and development of novel nanomolar F508-del CFTR correctors
XXV EFMC International Symposium on Medicinal Chemistry
2017
Bandiera T., Sorana F., Berti F., Rodriguez-Gimeno A., Di Fruscia P., Brindani N., Mandrup Bertozzi S., Ottonello G., Armirotti A., Spanò R., Bertorelli R., Penna I., Margaroli N., Russo D., Caci E., Ferrera L., Tomati V., Pesce E., Scudieri P., Bertozzi F., Pedemonte N., Galietta L.J.V.
DISCOVERY AND CHARACTERIZATION OF POTENT F508DEL-CFTR CORRECTORS
North American Cystic Fibrosis Conference
2017
Petracca R., Ponzano S., Bertozzi S.M., Sasso O., Piomelli D., Bandiera T., Bertozzi F.
Progress in the development of β-lactams as N-Acylethanolamine Acid Amidase (NAAA) inhibitors: Synthesis and SAR study of new, potent N-O-substituted derivatives
European Journal of Medicinal Chemistry, vol. 126, pp. 561-575
2016
Bonezzi F.T., Sasso O., Pontis S., Realini N., Romeo E., Ponzano S., Nuzzi A., Fiasella A., Bertozzi F., Piomelli D.
An important role for N-acylethanolamine acid amidase in the complete freund's adjuvant rat model of arthritis
Journal of Pharmacology and Experimental Therapeutics, vol. 356, (no. 3), pp. 656-663
2016
Nuzzi A., Fiasella A., Ortega J.A., Pagliuca C., Ponzano S., Pizzirani D., Bertozzi S.M., Ottonello G., Tarozzo G., Reggiani A., Bandiera T., Bertozzi F., Piomelli D.
Potent α-amino-β-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure-activity relationship (SAR) studies
European Journal of Medicinal Chemistry, vol. 111, pp. 138-159
2016
Diamanti E., Bottegoni G., Goldoni L., Realini N., Pagliuca C., Bertozzi F., Piomelli D., Pizzirani D.
Pyrazole-Based Acid Ceramidase Inhibitors: Design, Synthesis, and Structure-Activity Relationships
Synthesis, vol. 48, (no. 17), pp. 2739-2756
2015
Petracca R., Bertozzi F., Ponzano S., Bandiera T.
2-Oxopyridine-1-carboxylates, highly reactive carbamoylating agents of β-hydroxy α-aminoacids
Tetrahedron Letters, vol. 56, (no. 22), pp. 2887-2891
2015
Romeo E., Ponzano S., Armirotti A., Summa M., Bertozzi F., Garau G., Bandiera T., Piomelli D.
Activity-Based Probe for N-Acylethanolamine Acid Amidase
ACS chemical biology, vol. 10, (no. 9), pp. 2057-2064
2015
Ribeiro A., Pontis S., Mengatto L., Armirotti A., Chiurchiu V., Capurro V., Fiasella A., Nuzzi A., Romeo E., Moreno-Sanz G., Maccarrone M., Reggiani A., Tarzia G., Mor M., Bertozzi F., Bandiera T., Piomelli D.
A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation
ACS chemical biology, vol. 10, (no. 8), pp. 1838-1846