• CSFT 9885
  • CSFT 9886
  • CSFT 9887
  • CSFT 9888
  • CSFT 9889
  • CSFT 9890
  • CSFT 9891
  • CSFT 9892
  • CFST 9894

The Systems and Synthetic Biology research lines is built upon its wide set of equipment and the multidisciplinary expertise of its enthusiastic and committed research staff to enforce a new mission: the development of cutting-edge technologies to achieve fast the ambitious targets set up in Paris (December 2015) by the COP21 assembly of 195 Countries to cope with the global warming effect.

Use of CO2 as raw material for the synthesis of chemicals, materials or fuels so as to achieve the square  effect of its removal from the atmosphere or the emission sources and the production of renewable products substituting fossil ones.

Distributed Manufacturing, i.e. the development of production systems fed by renewable energy sources (heat, radiation, electric power, organic wastes) and following the distributed nature of these sources with a proper scale-down and process intensification to achieve cost-effective synthesis of high-added-value products (e.g. bioplastics, anti-oxidants, medicines, methane, hydrogen, biofuels, etc.) through electro-, bio- or photochemical techniques

Low temperature heat storage and exploitation, released or lost in the atmosphere for economic reasons from various application contexts (process industry, automobiles, residential heat and power plants, etc.), or generated from renewable energy sources (e.g. solar thermal, geothermal sources).

New premises and selected investments in key research areas (Synthetic and Systems Biology) and services (Multiscale Modelling) provide this Centre with a unique mix of synergistic competences distributed in four main divisions: Advanced materials, Additive Manufacturing, Reactors and Processes, Synthetic and Systems Biology.

A strategic alliance with the Politecnico di Torino is enforced on the above mentioned research themes.

Common lab spaces:

  • Nano materials Lab.
  • TEM lab.
  • FIB-FESEM lab.
  • Chemical systhesis and material processing lab.
  • CHEM lab.
  • Multiscale modelling Lab
  • Electronics for control, power management and on board diagnostics (in cooperation with the Department of Electronics and Telecommunications of Politecnico di Torino)


The main goal of the Additive Manufacturing (AM) division is the development of advanced novel materials  to fabricate lightweight functional systems, passing through a bio-inspired design, complex in their structure, shape, size, hierarchy, surface and materials usage. A joint initiative with Politecnico di Torino is enforced.

The whole group conducts research in all facets of additive manufacturing processes such as:

  • Development of advanced structural materials (lightweight alloys and composites, titanium alloys and composites, high-temperature alloys) for Selective Laser Melting
  • Characterization at the nano-scale
  • Surface post processing
  • Strengthen the design capabilities to produce lightweight complex shapes, non-assembly parts and bioinspired structures (radiant burners, heat exchangers, percolative structures, etc.
  • Improvement of additive manufacturing/3D printing techniques

AM Laboratories

  • AMMLab - Direct Metal Laser Sintering Machine (DMLS - EOSINT M270 Dual Mode), sand-blasting machine (SD9 Northblast)
  • HTLab - Heat treatments oven (up to 1200°C in high vacuum  or inert atmosphere)
  • REMLab - Gom’s Atos Compact Scan 2M (scanner 3D), RPT 80 Roughness tester

External Collaborations and Projects

STAMP, “Sviluppo Tecnologico dell’Additive Manufacturing in Piemonte(2016-2019) – Regional Project, Fabbrica Intelligente

HELMETH, “Integrated High-Temperature Electrolysis and Methanation for Effective Power to Gas Conversion” (2014-2016) - European Project FP7

CONTR. ASE “Ottimizzazione e realizzazione di un componente strutturale di uno starter generator grazie ai benefici derivanti dall’utilizzo di tecnologie additive” (2015-2016)

CONTR. ASI “Portable On board Printer 3D” (2014-2016)

CONTR. FBK “Realizzazione di particolari meccanici mediante tecnologia additiva Direct Metal Laser Sintering (DMLS)” (2015)

CONTR. ASTRA “Design e fabbricazione di uno scambiatore di calore mediante tecnologia additiva Direct Metal Laser Sintering (DMLS)” (2014)


  1. F. Calignano, M. Lorusso, J. Pakkanen, F. Trevisan, E. P. Ambrosio, D. Manfredi, P. Fino, Investigation of accuracy and dimensional limits of part produced in aluminum alloy by selective laser melting, The International Journal of Advanced Manufacturing Technology 2016, DOI: 10.1007/s00170-016-8788-9
  2. M. Cabrini, S. Lorenzi, T. Pastore, S. Pellegrini, E.P. Ambrosio, F. Calignano, D. Manfredi, M. Pavese, P. Fino, Effect of heat treatment on corrosion resistance of DMLS AlSi10Mg alloy, Electrochimica Acta 2016, DOI: 10.1016/j.electacta.2016.04.157
  3. F. Calignano, T. Tommasi, D. Manfredi, A. Chiolerio, Additive Manufacturing of a Microbial Fuel Cell—A detailed study, Scientific Reports 2015, DOI: 10.1038/srep17373
  4. D. Manfredi, F. Calignano, M. Krishnan, R. Canali, E.P. Ambrosio, E. Atzeni, From Powders to Dense Metal Parts: Characterization of a Commercial AlSiMg Alloy Processed through Direct Metal Laser Sintering, Materials, 2013, DOI: 10.3390/ma6030856
  5. F. Calignano, D. Manfredi, E. P. Ambrosio, L. Iuliano, P. Fino, Influence of process parameters on surface roughness of aluminum parts produced by DMLS, Int J Adv Manuf Technol 2013, DOI: 10.1007/s00170-012-4688-9

The main goal of the Reactors and Processes division is to develop a new class of reactors and devices for the valorisation of renewable sources (organic wastes, solar energy, renewable electricity, renewable heat). This spans over a wide range of reactors:

  • Microbial Fuel Cells for environmental monitoringand water-soil remediation
  • Electrochemical and bio-electrochemical reactors
  • (Photo)-biological reactors
  • Enzymatic structured reactors
  • Photo-electro-chemical reactors for solar fuels synthesis
  • H2 production, storage and utilisation systems, including artificial leafs
  • Long term thermal storage modules

RP Laboratories

  • Facilities for Nano Materials Synthesis: Paar Reactor, Microwave Reactor, CO2 Supercritical Dryer, Freeze Dryer, Electrospinner
  • Electrochemical Characterization: RRDE, Arbin BT-2000 test station, Potentiostat and galvanostat, test bench for bio fuel cell characterization
  • Biology: incubators for bacteria growth, biological and chemical woods

External Collaborations and Projects

"Microbial Fuel Cells as Underwater Power Enablers for Sensors _ MUES", project in collaboration with the SPAWAR (Space and Naval Warfare Systems Command) of the USA Navy.

"New Catalytic Materials for Innovative Cathodes in Microbial Fuel Cells for Long-Term Energy Production in Marine Systems", ONRG NICOP grant

FP7-NMP Eco2CO2 "Eco-friendly biorefinery fine chemicals from CO2 photocatalytic reduction" (2012-2016).

H2020-ISIB CELBICON "Cost-effective CO2 conversion into chemicals via combination of Capture, ELectrochemical and BIochemical CONversion technologies" (2016-2019)

H2020-LCE STORE&GO "Innovative large-scale energy STOragE technologies AND Power-to-Gas concepts after Optimisation" (2016-2019)


  1. N. Garino, A. Sacco, M. Castellino, J.A. Muñoz-Tabares, A. Chiodoni, V. Agostino, V. Margaria, M. Gerosa, G. Massaglia, M. Quaglio, Microwave-Assisted Synthesis of Reduced Graphene Oxide/SnO2 Nanocomposite for Oxygen Reduction Reaction in Microbial Fuel Cell, ACS Applied Materials & Interfaces, 2016, DOI: 10.1021/acsami.5b11198
  2. L. Delmondo, G.P. Salvador, J.A. Muñoz-Tabares, A. Sacco, N. Garino, M. Castellino, M. Gerosa, G. Massaglia, A. Chiodoni, M. Quaglio, Nanostructured MnxOy for oxygen reduction reaction (ORR) catalysts, Applied Surface Science, 2016, DOI: 10.1016/j.apsusc.2016.03.224
  3. S. Hernandez,   D. Hidalgo,   A. Sacco,   A. Chiodoni,   A. Lamberti,   V. Cauda,   E. Tresso,   G. Saracco , Comparison of photocatalytic and transport properties of TiO2 and ZnO nanostructures for solar-driven water splitting, Physical Chemistry Chemical Physics, 2015, DOI: 10.1039/C4CP05857G
  4. A. Vitale, M. Quaglio, A. Chiodoni, K. Bejtka, M. Cocuzza, C.F. Pirri, R. Bongiovanni, Oxygen-Inhibition Lithography for the Fabrication of Multipolymeric Structures, Advanced Materials, 2015, DOI: 10.1002/adma.201501737
  5. S. Hernandez, S. Bensaid, M. Armandi, A. Sacco, A. Chiodoni, B. Bonelli, E. Garrone, C.F. Pirri, G. Saracco, A new method for studying activity and reaction kinetics of photocatalytic water splitting systems using a bubbling reactor, Chemical Engineering Journal, 2014, DOI: 10.1016/j.cej.2013.08.094

This brand new division has been launched with an International Tenure track call to enable the sustainable production of chemicals, materials and fuels. In particular, the division will be focused on the design and optimization of microorganisms (cyanobacteria, clostridia, etc.) to produce valuable product from sunlight, CO2 and water, or from CO2 and renewable H2 mixtures. A synergy with the Politecnico di Torino and the Ennvironment Park will be enforced in this fields to maximize the results. The main activities encompassed in this division will be:

  • Synthetic biology approach for the manufacturing of added value products from wastes supported by systems biology tools for the optimization of the productive process
  • Enzyme optimization and genome engineering
  • Metabolic engineering
  • Natural photosynthesis (in cooperation with the  Biosolar Lab from PoliTo)

SSB Laboratories

  • Biosolar lab
  • Bioenergy Lab
  • Green Chemistry
  • Gene editing and analysis

External Collaborations and Projects

  • Imperial College London Prof. J. Barber)
  • University of Padoa (Prof. T. Morossinotto)
  • Queen Mary University of London (Dr. J. Nield)
  • University of Amsterdam (Prof. K. Hellingwerf)
  • University of Nottingham (Prof. N. Minton)


  1. Albanese, P., Nield, J., Tabares, J.A.M., Chiodoni, A., Manfredi, M., Gosetti, F., Marengo, E, Saracco, G., Barber, J., Pagliano, C., Isolation of novel PSII-LHCII megacomplexes from pea plants characterized by a combination of proteomics and electron microscopy, Photosynthesis Research, 2016, in press, DOI: 10.1007/s11120-016-0216-3
  2. Pagliano, C., Nield, J., Marsano, F. Pape, T., Barera, S., Saracco, G., Barber, J., Proteomic characterization and three-dimensional electron microscopy study of PSII-LHCII supercomplexes from higher plants, Biochimica et Biophysica Acta – Bioenergetics, Vol. 1837, Issue 9, 2014, 1454-1462; DOI: 10.1016/j.bbabio.2013.11.004
  3. Pagliano, C., Saracco, G., Barber, J., Structural, functional and auxiliary proteins of photosystem II, 2013,Photosynthesis Research  116 (2-3), pp. 167-188, DOI: 10.1007/s11120-013-9803-8
  4. Barera, S., Pagliano, C., Pape, T., Saracco, G., Barber, J., Characterization of PSII-LHCII supercomplexes isolated from pea thylakoid membrane by one-step treatment with α- and β-dodecyl-D-maltoside, 2012, Philosophical Transactions of the Royal Society B: Biological Sciences, 367 (1608), pp. 3389-3399, DOI: 10.1098/rstb.2012.0056