Research at IIT is carried out in the main laboratory in Genoa, 11 research centers across Italy and 2 outstations in US.

IIT scientific plan 2015-2017 encompassesed 11 programs relating to 3 main areas (Technology oriented, Core and Cross Disciplinary programs). Each program is developed  by a number of fully independent Principal Investigators (PIs) working in the main laboratory or the research centers. 

Since January 2018 a new Strategic Plan has been activated.

Each center is coordinated by a director and its PIs and teams may contribute to one or more Programs while developing their research lines according to the Research Matrix developed by the Institute.

There are currently 72 independent PIs at IIT developing the research activities in a fully cross-disciplinary research environment. Scientists with 21 different profiles  (spanning from medicine to engineering) work together to implement the Institute’s Strategic Plan 2018-2023.