GenEdiDS

GenEdiDS
ERC Consolidator Grant 2017-2022

Rescuing Cognitive Deficits in Neurodevelopmental Disorders by Gene Editing in Brain Development: the Case of Down Syndrome.

The project aims at investigating whether gene editing in a subpopulation of neuronal progenitors in the developing central nervous system can ameliorate cognitive impairment in mouse models of Down syndrome. Investigations on innovative in vivo delivery systems for the gene editing tools at higher translational value will complete the project.