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Raffaele Spano

Support Technician
Nanotechnology for Precision Medicine
Research center
About

Dr. Raffaele Spanò is a Support Technician in the Nanotechnology for Precision Medicine research line at Istituto Italiano di Tecnologia since July 2019. His research activities focus on the development of Discoidal Polimeric Nano-Constructs carrying thrombolytic drugs (e.g. Tissue-Type Plasminogen Activator), for therapeutic applications in vascular diseases.

In January 2013, he started his PhD in Tissue Engineering and Regenerative Medicine under the supervision of Prof. Ranieri Cancedda and Dr. Maddalena Mastrogiacomo. During this period he worked on the development of Human Platelet-Rich Plasma-based additive for cell culture and of dressings to enhance skin hound healing. All this work was collected in his thesis with the title "Platelet derivatives: from the Laboratory bench to the bedside".

Dr Spanò achieved his MSc Degree in Applied Science, Medical and Pharmaceutical Biotechnology in November 2011 at the Università degli Studi di Genova, discussing the thesis “Alteration of bone turnover and growth plate in transgenic mice overexpressing Lipocalin-2 in bone”.


Education

Title: Ph.D. in Tissue Engineering and Regenerative Medicine
Institute: Università degli Studi di Genova
Location: Genova
Country: Italy
From: 2013 To: 2016

Title: Master Degree in Applied Science, Medical and Pharmaceutical Biotechnology
Institute: Università degli Studi di Genova
Location: Genova
Country: Italy
From: 2006 To: 2011

All Publications
2021
Di Mascolo D., Palange A.L., Primavera R., Macchi F., Catelani T., Piccardi F., Spano R., Ferreira M., Marotta R., Armirotti A., Gallotti A.L., Galli R., Wilson C., Grant G.A., Decuzzi P.
Conformable hierarchically engineered polymeric micromeshes enabling combinatorial therapies in brain tumours
Nature Nanotechnology, vol. 16, (no. 7), pp. 820-829
Article Journal
2019
Soldani G., Murzi M.b., Faita F.C., Di Lascio N.C.D., Al Kayal T.A., Spanò R., Canciani B., Losi P.
In vivo evaluation of an elastomeric small-diameter vascular graft reinforced with a highly flexible Nitinol mesh
Journal of Biomedical Materials Research - Part B Applied Biomaterials
Article Journal
2019
Contardi M., Russo D., Suarato G., Heredia-Guerrero J.A., Ceseracciu L., Penna I., Margaroli N., Summa M., Spano R., Tassistro G., Vezzulli L., Bandiera T., Bertorelli R., Athanassiou A., Bayer I.S.
Polyvinylpyrrolidone/hyaluronic acid-based bilayer constructs for sequential delivery of cutaneous antiseptic and antibiotic
Chemical Engineering Journal, vol. 358, pp. 912-923
Article Journal
2018
Suarato G., Spano' R., Bertorelli R., Diaspro A., Athanassiou A., Surdo S.
3D-printed, pocket-size diffusion cells for skin permeation investigation
Eurosensors 2018 Conference
Conference Paper Conference
2018
Bandiera T., Sorana F., Berti F., Rodríguez-Gimeno A., Brindani N., Bertozzi S.M., Ottonello G., Armirotti A., Spanò R., Summa M., Bertorelli R., Penna I., Margaroli N., Russo D., Caci E., Ferrera L., Tomati V., Sondo E., Pesce E., Scudieri P., Bertozzi F., Pedemonte N., Galietta L.J.V.
New correctors rescue f508del-cftr activity at low nanomolar concentrations
European Cystic Fibrosis Society (ECFS) Basic Science Conference
Poster Conference