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Luca Pandolfini

Researcher
Researcher
Non-coding RNAs and RNA-based therapeutics
Telefono
+39 010 2897 623
Indirizzo
Via Enrico Melen 83, Building B 16152 Genova, Italy
Research center
CHT@Erzelli
Interests
Neural Stem Cells
RNA modifications
Planaria
Biografia
Education

Title: PhD in Neurobiology
Institute: Scuola Normale Superiore di Pisa
Location: Pisa
Country: Italy
From: 2011 To: 2015

Title: Master’s degree in Molecular and Cell Biology
Institute: Scuola Normale Superiore di Pisa
Location: Pisa
Country: Italy
From: 2009 To: 2011

Experience External

Title: Research Associate
Institute: Gurdon Institute - University of Cambridge
Location: Cambridge
Country: United Kingdom
From: 2015 To: 2019

Top Publications
2023
Pierattini B., D'Agostino S., Bon C., Peruzzo O., Alendar A., Codino A., Ros G., Persichetti F., Sanges R., Carninci P., Santoro C., Espinoza S., Valentini P., Pandolfini L., Gustincich S.
SINEUP non-coding RNA activity depends on specific N6-methyladenosine nucleotides
Molecular Therapy - Nucleic Acids, vol. 32, pp. 402-414
DOI 10.1016/j.omtn.2023.04.002
Article Journal
2022
Dunville K., Tonelli F., Novelli E., Codino A., Massa V., Frontino A.M., Galfrè S., Biondi F., Gustincich S., Caleo M., Pandolfini L., Alia C., Cremisi F.
Laminin511 and WNT signalling sustain prolonged expansion of hiPSC-derived hippocampal progenitors.
Development (Cambridge)
DOI 10.1242/dev.200353
2022
Valentini P., Pierattini B., Zacco E., Mangoni D., Espinoza S., Webster N.A., Andrews B., Carninci P., Tartaglia G.G., Pandolfini L., Gustincich S.
Towards SINEUP-based therapeutics: Design of an in vitro synthesized SINEUP RNA
Molecular Therapy - Nucleic Acids, vol. 27, pp. 1092-1102
DOI 10.1016/j.omtn.2022.01.021
Article Journal
2021
Leger A., Amaral P.P., Pandolfini L., Capitanchik C., Capraro F., Miano V., Migliori V., Toolan-Kerr P., Sideri T., Enright A.J., Tzelepis K., van Werven F.J., Luscombe N.M., Barbieri I., Ule J., Fitzgerald T., Birney E., Leonardi T., Kouzarides T.
RNA modifications detection by comparative Nanopore direct RNA sequencing
Nature Communications, vol. 12, (no. 1)
DOI 10.1038/s41467-021-27393-3
2019
Pandolfini L., Barbieri I., Bannister A.J., Hendrick A., Andrews B., Webster N., Murat P., Mach P., Brandi R., Robson S.C., Migliori V., Alendar A., d'Onofrio M., Balasubramanian S., Kouzarides T.
METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation
Molecular Cell, vol. 74, (no. 6), pp. 1278-1290.e9
DOI 10.1016/j.molcel.2019.03.040