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Barbara Spagnolo

Technician
Multifunctional Neural Interfaces with deep-brain regions
Phone
Research center
About

Barbara Spagnolo graduated summa cum laude in Neurobiology, at University of Torino , by disserting a thesis on “Analysis of motor nervous systems and motor performance of APPPS1 mice, model for Alzheimer Disease”. Working on this subject she was involved in electrophysiological, behavioral and immunohistochemical experiments and data analysis. This included animal handling during in vivo experiments to analyze motor skills, neurosurgery (cerebellar peduncle lesions), single and multiunit electrophysiology and mouse perfusion/fixation. After a PhD in Biomolecular Nanotechnologies  focused on the application of 3D micro and nanofabrication approaches applied to life science (cancer), she worked on the development of transgenic cell lines for optogenetics. In the last four years she also developed different optrode designs for simultaneous optical control and electrophysiological readout of neural activity and tested them in vivo. In 2021 she started to work in IIT@CBN as a support Technician for the Multifunctional Neural Interfaces with Deep Brain Areas research line where she manages and performs activities and experiments related to the in vivo testing of newly developd optoelectronic devices, partecipating also in their design and fabrication. Additionally, she is responsible for the draw up of the animal use protocols, required in research activities/projects involving vertebrate animals.



All Publications
2021
Pisanello M., Balena A., Pisano F., Spagnolo B., Bianco M., Sileo L., Pisanello F., De Vittorio M.
Back-end processing of optoelectronic devices for neural interfaces based on tapered optical fibers
47th International conference on Micro and Nano Engineering
Poster Conference
2021
Montinaro C., Pisanello M., Bianco M., Spagnolo B., Pisano F., Balena A., De Nuccio F., Lofrumento D. D., Verri T., De Vittorio M., Pisanello F.
Estimating fiber photometry collection volumes across different brain regions
LEbiotec2021
Poster Conference
2021
Montinaro C., Spagnolo B., Pisanello M., Pisano F., Balena A., Bianco M., Brunetti V., De Nuccio F., Lofrumento D. D., Verri T., De Vittorio M., Pisanello F.
Estimating the Spatial Behavior of Fiber Photometry Across Different Brain Regions
OSA Biophotonics Congress
Conference Paper Conference
2021
Spagnolo B., Peixoto Rui T., Sileo L., Pisanello M., Pisano F., Assad J.A., Sabatini B.L., De Vittorio M., Pisanello F.
Fibertrodes: a FIB based fabrication approach for interfacing brain activity with negligible photoelectric noise
MNE 2021
Conference Paper Conference
2021
Spagnolo B., Balena A., Peixoto Rui T., Sileo L., Pisanello M., Pisano F., Assad J.A., Sabatini B.L., De Vittorio M., Pisanello F.
Fibertrodes: a FIB based fabrication approach for interfacing brain activity with negligible photoelectric noise
MNE
Conference Paper Conference
Scientific Talks
2021
Balena A., Spagnolo B., Bianco A., Pisanello M., Pisano F., Rizzo A., Sileo L., De Nuccio F., Lofrumento D., Sabatini B. L., Pisanello F., De Vittorio M.
Non-planar two-photon lithography on tapered fibers to realize implantable interfaces for simultaneous multipoint optical control and electrical recording of neural activity
Laboratoire Kastler Brossel
Institute
2020
Pisanello M., Spagnolo B., Sileo L., Pisano F., Balena A., Pisanello F., De Vittorio M.
Advanced optoelectronic devices for neuroscience
International Conference on Transparent Optical Networks
Conference
2020
Pisano F., Pisanello M., Lee S. J., Lee J., Maglie E., Balena A., Sileo L., Spagnolo B., Bianco M., Hyun M., Sabatini B. L., De Vittorio M., Pisanello F.
Depth-resolved optical monitoring of neural activity in freely moving animals
22nd International Conference on Transparent Optical Networks (ICTON)
Conference
2019
Maglie E., Pisanello M., Pisano F., Balena A., Spagnolo B., Sabatini B.L., De Vittorio M., Pisanello F.
Modeling brain tissue scattering for optical neural interfaces
International Conference on Transparent Optical Networks ICTON 2019
Conference
2019
Pisano F., Pisanello M., Balena A., Kashif M.F., Maglie E., Rizzo A., Lemma E.D., Spagnolo B., Bianco M., Sileo L., Qualtieri A., Stomeo T., Lee S.J., Lee J., D'Orazio A., Sabatini B.L., Grande M., De Vittorio M., Pisanello F.
Multifunctional neural interfaces combining optics, photonics and nanotechnology
Universita di Torino
Institute
Oral presentations
2021
Spagnolo B., Peixoto Rui T., Sileo L., Pisanello M., Pisano F., Assad J.A., Sabatini B.L., De Vittorio M., Pisanello F.
Fibertrodes: a FIB based fabrication approach for interfacing brain activity with negligible photoelectric noise
MNE 2021
Conference
2021
Spagnolo B., Balena A., Peixoto Rui T., Sileo L., Pisanello M., Pisano F., Assad J.A., Sabatini B.L., De Vittorio M., Pisanello F.
Fibertrodes: a FIB based fabrication approach for interfacing brain activity with negligible photoelectric noise
MNE
Conference
2021
Spagnolo B., Sileo L., Pisanello M., Pisano F., Balena A., DeVittorio M., Pisanello F.
Interfacing with small brain volumes taperedfiber-based optrode
OSA: Biophotonics Congress
Conference
2020
Spagnolo B., Pisanello M., Sileo L., Pisano F., Balena A., Pisanello F., DeVittorio M.
Advanced optoelectronic devices for neuroscience
ICTON 2020
Conference
2019
Spagnolo B., Sileo L., Peixoto R., Pisanello M., Pisano F., Maglie E., Sabatini B., Pisanello F., De Vittorio M.
A single integrated fiberoptrode for optogenetic stimulation and electrical recording of neural activity
MNE 2019
Conference