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Denis Garoli

Post Doc
Researcher

Research Line

Optoelectronics

Center

IIT Central Research Labs Genova

Contacts

Via Morego 30
Contact Me

About

Born in Padova , get a master Degree in Physics at Padova University. I awarded a PhD in Space Science and Technology at University of Padova with a thesis on the development of innovative technologies for the environmental conservation. In 2011 I get a Degree in Biotechnology at Padova University.
Between 2007 and 2009 I mainly worked on material science R&D for space applications also taking part to a Space Agency’s project (during my collaboration with Media-Lario Technologies – see D. Garoli et al. doi.org/10.1117/12.820428). After this first industrial experience I back to academic research starting my collaboration with Laboratory for Nanofabrication of Nanodevices (LaNN - Venetonanotech) and University of Padova in Padova where I was scientist in charge with Clean Room facilities for nanofabrication. There I extended my view from coatings and material-science to plasmonics and nanotechnologies focusing on nanofabrication and optical applications (see for example D. Garoli et al. doi.org/10.1364/OE.20.016224; doi.org/10.1116/1.4769975).

In the end of 2014 I moved to Istituto Italiano di Tecnologia (IIT), where I’m working as researcher. In 2015 I proposed the idea and write the winning Horizon 2020 FET project ProseqO (co-coordinator and main WP leader within two italian partners – rank #1 among more than 900 proposals): PROtein SEQuencing using Optical single molecule real-time detection. The project regards the development of new technologies for single molecule detection and manipulation with the final goal of DNA/RNA and protein sequencing. Within this project I also started a continuous collaboration with the Biotech company AbAnalitica in Padova (partner in FET project) where I coordinate the ProseqO project and supports the R&D activities. The main results of the research during these years regard the design, fabrication and test of innovative plasmonic devices for several applications, from material science, to biosensing and optical beam manipulation (see list of publication below). During the last two years I mainly focused my activities on nanopore technology for single molecule detection and significant results of the work are now published or under review in high level journals.

Interests

Single molecule spectroscopy nanopores 2D materials plasmonics

Projects

Horizon 2020 FET Open ProseqO (2016 - 2019) - Coordinator

The project regards the development of new technologies for single molecule detection and manipulationwith the final goal of DNA/RNA and protein sequencing. In particular, the advent of analytical techniques withextremely low limits of detection has led to dramatic progresses in the field of nucleic acids sequencing. Despitethe development of next generation sequencing platforms, the current genome sequencing task remains formidable, and revolutionary advances in DNA sequencing technology are still demanded. Another technological revolution would be a fast and reliable sequencing of proteins, which are the primary actors invirtually all life processes and are coded by DNA sequences known as genes.

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