Emotion Discrimination Task part1

Emotion Discrimination Task

Fear Emotion Discrimination test for mice. (A) Schematic drawing of the test setting. (B) Timeline of pre-test and test procedures to evoke in one of the demonstrators a ‘‘fear’’ state by delivering the conditioned tone in the 2- to 4-min epoch. (C and D) Time (in seconds) spent sniffing demonstrators in neutral (gray bars) or tone-induced fear (red bars) state displayed by (C) male and (D) female observer mice during the 6-min test, divided into three consecutive 2-min epochs. *p < 0.05 versus the exploration of the neutral demonstrator. n = 8/15 observers per group. Modified from Ferretti et al Current Biology 2019.

Emotion Discrimination Task part2

Relief Emotion Discrimination test for mice. (A) Schematic drawing of the test setting. (B) Timeline of pre-test and test procedures to evoke in one of the two demonstrators a ‘‘relief’’ state during the testing phase. (C and D) Time (in seconds) spent sniffing demonstrators in neutral (gray bars) or water-induced relief (yellow bars) states displayed by (C) male and (D) female observer mice during the 6 min of the test, divided into three consecutive 2-min epochs. **p < 0.005 versus the exploration of the neutral demonstrator. n=15 observers per group. Modified from Ferretti et al Current Biology 2019.