Advanced in vitro physiological models: Towards real-scale, biomimetic and biohybrid barriers-on-a-chip

The project is focused on the design, production, and proposal for commercialization of the first 1:1 scale 3D printed realistic model of the brain tumor microenvironment, with its associated blood neurovasculature. The proposed model can be easily adopted as multi-compartmental scaffold for the development of advanced co-culture systems.

Magnetic Solid Lipid Nanoparticles as a Multifunctional Platform against Glioblastoma Multiforme

The SLaMM project aims at the development of multifunctional lipid-based nanovectors for the delivery and the targeting of drugs to the brain, in the treatment of extremely aggressive brain tumors. The nanovectors will be tested on a specifically developed in vitro model, before their final validation in vivo.