IIT Publications Search

Publications
2023
Ruiz Munevar M.J., Rizzi V., Portioli C., Vidossich P., Cao E., Parrinello M., Cancedda L., De Vivo M.
Cation Chloride Cotransporter NKCC1 Operates through a Rocking-Bundle Mechanism
Journal of the American Chemical Society
2023
Smith J.B., Cancedda L., Jozwiak S., Mercer A.C.
Editorial: Viral vector-based gene therapy in neurological disease: The future is now
Frontiers in Neurology, vol. 14
2023
Prakasam R., Bonadiman A., Andreotti R., Zuccaro E., Dalfovo D., Marchioretti C., Tripathy D., Petris G., Anderson E.N., Migazzi A., Tosatto L., Cereseto A., Battaglioli E., Soraru G., Lim W.F., Rinaldi C., Sambataro F., Pourshafie N., Grunseich C., Romanel A., Pandey U.B., Contestabile A., Ronzitti G., Basso M., Pennuto M.
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice
Nature Communications, vol. 14, (no. 1)
2023
Savardi A., Patricelli Malizia A., De Vivo M., Cancedda L., Borgogno M.
Preclinical Development of the Na-K-2Cl Co-transporter-1 (NKCC1) Inhibitor ARN23746 for the Treatment of Neurodevelopmental Disorders
ACS Pharmacology and Translational Science, vol. 6, (no. 1), pp. 1-11
Article Journal
2023
Savardi A., Colombi I., Alberti M., Parrini M., Ziogas I., Borgogno M., De Vivo M., Contestabile A., Cancedda L.
Role of Intracellular Chloride Accumulation in Down Syndrome Physiopathology and Therapeutic Strategies
XXI Telethon Scientific Convention
Poster Conference
2023
Savardi A., Borgogno M., De Vivo M., Cancedda L.
Selective NKCC1 Inhibitors for the Treatment of Drug-Resistant Epilepsy
Discussione in Epilessia Sperimentale 2
Poster Conference
2023
Savardi A., Borgogno M., De Vivo M., Cancedda L.
Selective NKCC1 Inhibitors for the Treatment of Neurodevelopmental and Neurological Disorders with defective NKCC1/KCC2 expression-ratio
American Academy of Neurology Annual Meeting
Poster Conference
2022
Cwetsch A.W., Ziogas I., Narducci R., Savardi A., Bolla M., Pinto B., Perlini L.E., Bassani S., Passafaro M., Cancedda L.
A rat model of a focal mosaic expression of PCDH19 replicates human brain developmental abnormalities and behaviours
Brain Communications, vol. 4, (no. 3)
2022
Stuefer A., Balasco L., Bertozzi S., Coletta L., Hayward A., Rocchi F., Montani C., Alvino F., Galbusera A., Aldrighetti M., Gini S., Curcic V., Papaleo F., Iurilli G., Cancedda L., Armirotti A., Bozzi Y., Gozzi A.
Chemogenetic excitation of pyramidal neurons during early development: a longitudinal behavioral and imaging study
SfN
Poster Conference
2022
Montani C., Hayward A., Gutierrez-Barragan D., Morelli G., Alvino F. G., Coletta L., Galbusera A., Pasqualetti M., Cancedda L., Gozzi A.
Chemogenetic stimulation of oxytocinergic neurons dynamically modulates fMRI connectivity
Annual Meeting of the Society for Neuroscience 2022
Poster Conference
2022
Montani C., Hayward A., Gutierrez-Barragan D., Morelli G., Alvino F., Coletta L., Galbusera A., Rocchi F., Pasqualetti M., Cancedda L., Gozzi A.
Chemogenetic stimulation of oxytocinergic neurons dynamically modulates fMRI connectivity
FENS Forum 2022
Poster Conference
2022
POTENZIERI A., UCCELLA S., PREITI D., ROSATI S., LAVARELLO C., DEBELLIS D., CATALANO F., MAROTTA R., PETRETTO A., TUCCI V., RAMENGHI L., SAVARDI A., CANCEDDA L.
Early IGF-1 Receptor Inhibition in Mice Mimics Preterm Human Brain Disorders
Annual Meeting of the Society for Neuroscience 2022
Poster Conference
2022
Savardi A., Malizia A.P., De Vivo M., Cancedda L., Borgogno M.
Preclinical development of the NKCC1 inhibitor ARN23746 for the treatment of neurodevelopmental disorders
ACS Pharmacology & Translational Science
Article in Press Journal
2022
Savardi A., Borgogno M., De Vivo M., Cancedda L.
Selective NKCC1 inhibitors for the treatment of Autism, Down syndrome and brain disorders with defective neuronal Cl homeostasis
FENS Forum 2022, Paris, France
Poster Conference
2022
Zhao Y., Roy K., Vidossich P., Cancedda L., De Vivo M., Forbush B., Cao E.
Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide
Nature Communications, vol. 13, (no. 1)

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