Dr. Gabriella Costabile is a Fondazione Veronesi Postdoctoral fellow in the Nanotechnology for Precision Medicine Laboratory (nPMed) of Prof. Paolo Decuzzi at Istituto Italiano di Tecnologia (GE, Italy) since April 2019.
Her research interests focus on the design and development of innovative delivery systems, from formulation design to preclinical in vivo evaluation, to allow a bioactive compound (i.e., low molecular weight drugs, peptides, proteins and nucleic acid therapeutics) to pass effectively through biological barriers in the body (i.e. airways, skin, BBB).
She received her M.S. degree in chemistry and pharmaceutical technology in 2012 at the University of Naples Federico II (IT). In 2016, she received her Ph.D. degree under the supervision of Prof. Francesca Ungaro in pharmaceutical sciences with a thesis titled “New strategies to deliver drugs for the local treatment of severe pulmonary diseases” at the University of Naples Federico II (IT). During her PhD, she received an award from the International Society for Aerosols in Medicine (ISAM) to spend time as visiting Ph.D. student in the laboratory of Prof. Rothen-Rutishauser at the Adolphe Merkle Institute, University of Fribourg (CH). Following her Ph.D. degree, in 2017 she joined the research group of Prof. Olivia M. Merkel at the Ludwig-Maximilians-University in Munich (DE), first as postdoc partially funded by the travel grant PROGRAMMA STAR-Linea 2 University of Napoli Federico II and then as group leader.
After being awarded with a 1 year fellowship with the Fondazione Veronesi, she joined the nPMed laboratory to design, develop and test nanoparticles for the treatment of brain cancer.
viaNOSE: Through the nose into the brain with bio-inspired polymeric nanoparticles for siRNA delivery in glioblastoma therapy