He did his Master's Degree in Manufacturing and Material Engineering in 2011, from University Technology Malaysia (UTM), Malaysia.
Currently, he's PhD Student in "BIOENGINEERING AND ROBOTICS " in the Scanning Probe Microscopy group of Nanophysics Department at the Italian Institute of Technology, Genova, Italy.
His current research interests in the field of Nanotechnology deal with dental composites, Anodic Porous Alumina fabrication and its application in different areas.
Anodic porous alumina (APA) is a nanostructured form of aluminum oxide that has already proven to be biocompatible and thus is potentially useful for permanent implants in orthopedics and dentistry. Label-free surface-enhanced Raman scattering (SERS) sensing based on gold (Au) coated APA substrate has also been reported, with both thick (>10 um) and thin (500-100 nm) or ultrathin (<50 nm) forms of APA (TAPA, tAPA and utAPA, respectively). We aim at a novel combination of APA as both a SERS sensor surface and a cell seeding substrate, additionally endowed with drug delivery capabilities of the pores. Initially, loading and subsequent elution of test pharmaceutical molecules (e.g. Diclofenac) or active nanoparticles (e.g. antibacterial silver or remineralizing hydroxyapatite) will be tested. Means of triggering the release or at least modulating its rate, by control of either the medium (temperature, pH, etc) or a sealing layer on top (e.g. lipid bilayer or polymer film) will be explored. The presence of loaded drugs/mNPs and its release can will be verified by optical techniques based on fluorescence labeling or by quartz crystal microbalance (QCM). Indirectly, their effect can be assessed by SERS on different types of living cells cultured on the bioactive Au-tAPA substrates (e.g. osteoblasts, fibroblasts, and even neurons). Alternative metals would also be investigated in the future (mainly titanium).
Another anodic oxide that may find applications in dentistry is that of titanium, the metal of which most permanent implants inserted in the bone are made. The anodization treatment is additive and can be combined with traditional micro-roughening (etching, sandblasting). Dental companies (Sweden&Martina, Nobel Biocare) have already patented anodization applied on their endosseous implants. However much room exists in improvement, in both aspects of surface pattern (texture, amplitude) and in functionalization of the surface to make it bioactive.