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Research activities at the IIT Center for Synaptic Neuroscience and Technology apply multidisciplinary approaches to study brain function and diseases, and seek to develop novel technologies for neuroscience applications.

Laboratories

The Center occupies about 700 sqm inside within the IRCCS San Martino University Hospital in Genova, a site of excellence for neurology and clinical neuroscience. The Center is provided with state-of-the-art electrophysiology, molecular neurobiology and neurotechnology facilities.

Patch-clamp and conventional electrophysiology

Twelve patch-clamp setups for primary neuron cultures and acute brain slices, five MEA setups and three in vivo physiology setups.

Cell culture

Primary and organotypic cultures, stem cells and viral preparations. 

Imaging

Histochemistry and immunocyto/histochemistry; 1 Leica SP8 confocal microscope; 1 Leica TIRF workstation; epifluorescence and chemiluminescence microscopes and Neurolucida system.

Cellular and molecular biology

PCR and real time-PCR machines, phosphoimagers, Biacore SPR, spectrophotometers.

Computation

Modeling and Molecular Dynamics simulations of neuronal proteins.

Animal facility

300 sqm laboratory area for general services and in vivo laboratories (surgery and behavior, EEG and mouse genetics).

Research Lines

The Center hosts the Neuroscience and Smart Materials line. Research activities focus on two main areas: Brain function and diseases, and Neurotechnologies for health. Read More