Researcher in “RNA synthesis” - [ Researcher ]

Workplace: Genova, IIT
Added on: 05/04/2019 - Expires on: 30/05/2019

“Computational and Chemical Biology” Research Line is looking for an experienced PhD level Scientist to head a new small research group devoted to the design, chemical synthesis and testing of innovative nucleic acid-based drugs.

Candidates’ areas of expertise should include short and long noncoding RNAs, siRNAs and antisense oligonucleotides.

The research activities in which the scientist will be particularly involved are  the use of chemical epitranscriptome modifications and the therapeutics for neurodevelopment and neurodegenerative diseases. The scientist will be also responsible for managing the operation of an oligonucleotide synthesis facility and an analytical team working on purification and quality assessment of the oligonucleotide products. The scientist will take advantage of the highly competitive environment in molecular and cellular neurobiology as well as in molecular modeling and drug design which IIT can offer. 

Main responsibilities:

  • Operate and maintain oligonucleotide synthesis machinery
  • Manage and develop a small team of nucleic acid scientists and RA’s
  • Assist in the development of new technology for the synthesis and application of oligonucleotides and other nucleic acid reagents
  • Perform advanced data analysis as well as trouble-shooting under minimal supervision
  • Communicate and report study findings at meetings
  • Work cooperatively with an advisory team to optimize screening strategies and develop functional assays
  • Contribute to group goals and objectives with new ideas and creative approaches.


  • This position requires a PhD in Chemistry, Biology and related disciplines, at least two years of postdoctoral experience, and at least three additional years of relevant experience.
  • A strong knowledge of nucleic acid biochemistry
  • Experience with chemical synthesis of nucleic acids is highly desirable
  • A high level of understanding of cellular and molecular biology and biochemistry experimental techniques
  • Ability to work independently but also to be a productive and cooperative member of a diverse research team
  • Ability to manage multiple projects
  • Prior experience in managing research groups is desirable
  • Strong written and oral communication skills

Salary will be commensurate to qualifications and experience and in line with international standards.

Please submit your applications, including detailed curriculum vitae, 3 representative publications and 3 pages of research statement in PDF format to, quoting “Researcher position “RNA synthesis” CB 76606” in the subject line.

Candidates should also request 3 evaluation letters from international experts, who should send them directly in PDF format to

 Deadline: May 30, 2019

The selection process will include a panel interview and a presentation.

Istituto Italiano di Tecnologia, with its headquarters in Genoa, Italy, is a non-profit institution with the primary goal of creating and disseminating scientific knowledge and strengthening Italy's technological competitiveness. IIT was established in 2003 and successfully created a large-scale infrastructure in Genova along with a network of 10 state-of-the-art laboratories countrywide. The institute has been recruiting an international staff of about 1200 people from more than 50 countries. Its research endeavour focuses on high-tech and innovation, representing the forefront of technology with possible application from medicine to industry, computer science, robotics, life sciences and nanobiotechnologies.

Please note that the data that you provide will be used exclusively for the purpose of professional profiles’ evaluation and selection, and in order to meet the requirements of Istituto Italiano di Tecnologia.

Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security.

Please also note that, pursuant to articles 15 et. seq. of European Regulation no. 679/2016 (General Data Protection Regulation), you may exercise your rights at any time by contacting the Data Protection Officer (phone +39 010 71781 - email: dpo[at]

Istituto Italiano di Tecnologia is an Equal Opportunity Employer that actively seeks diversity in the workforce.

Involved Research lines
Computational and Chemical Biology


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