Post-doctoral position - Laboratory of Cancer Biology - [ Postdoc ]

Workplace: Milano, IIT@SEMM
Added on: 04/02/2019 - Expires on: 19/02/2019

We are seeking a post-doctoral candidate to join the Cancer Biology team lead by Dr. Stefano Campaner within the Genomic Science Research Line at the Center for Genomic Science of Istituto Italiano di Tecnologia (IIT) in Milan, Italy (https://cgs.iit.it/research/cancer-biology), coordinator Dr. Francesco Nicassio. Our group has a long-standing interest in understanding the molecular mechanisms of transformation induced by oncogenic transcription factors such as Myc and the Hippo pathway co-activators YAP and TAZ.

The successful candidate will be involved in the study of the transcriptional co-activators YAP and TAZ, focusing in particular on their role in lineage restriction and in the control of cellular proliferation. This study is based on a combination of in-vivo and in-vitro studies aimed at dissecting the role of YAP/TAZ by using genome wide chromatin studies (ChIP-seq, ATAC-seq) coupled with genome wide mRNA expression (RNA-seq, Quanta-seq and SLAM-seq) and single cell analyses (sc-RNA-seq and sc-ATAC-seq). We are seeking a highly motivated, ambitious and talented scientist to join our lab. The ideal candidate should be highly skilled in computational biology and bioinformatics, with proven experience in coding using both scripting languages as C/C++, Phyton and statistical languages as R.

Ability to program, operate and transfer data in Unix, Linux and Macintosh OS X systems will be a plus. Problem solving abilities and a team working attitude will be essential.

The Center for Genomic Science of IIT@SEMM (http://genomics.iit.it ) is located in Milan, Italy and is one of IIT’s national nodes. The Center benefits from state-of-the-art facilities and advanced technologies. The successful candidate will be integrated in a lively community of experimental and computational scientists.

Required skills and experience

  • A PhD in Computational Biology/Bioinformatics with or without post-doctoral experience.
  • Documented research experience in Computational Biology as well as in cellular and cancer biology.
  • Fluency in written and oral English.

Applications should be e-mailed both to applications@iit.it and stefano.campaner@iit.it and include a CV, contacts and name of 2 referees and a short statement about professional skills and interests.

Application deadline: February 19, 2019

Fondazione Istituto Italiano di Tecnologia – IIT (www.iit.it) - was founded with the objective of promoting Italy’s technological development and further education in science and technology. In this sense IIT is committed to achieving its scientific program, which sees a major inspirational principle in the integration between basic scientific research and the development of technical applications. Research at IIT cover scientific areas of high innovative content, representing the most advanced frontiers of modern technology, with wide application possibilities in various fields from medicine to industry, from computer science to robotics, life sciences and nanobiotechnology.

Istituto Italiano di Tecnologia is an Equal Opportunity Employer that actively seeks diversity in the workforce.

Please note that the data that you provide will be used exclusively for the purpose of  professional profiles’ evaluation and selection, and in order to meet the requirements of Istituto Italiano di Tecnologia.

Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security.

Please also note that, pursuant to articles 15 et. seq. of European Regulation no. 679/2016 (General Data Protection Regulation), you may exercise your rights at any time by contacting the Data Protection Officer (phone +39 010 71781 - email: dpo[at]iit.it)

Contacts

applications@iit.it
Stefano Campaner
stefano.campaner@iit.it
Involved Research lines
Genomic Science

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I numeri di IIT

L’Istituto Italiano di Tecnologia (IIT) è una fondazione di diritto privato - cfr. determinazione Corte dei Conti 23/2015 “IIT è una fondazione da inquadrare fra gli organismi di diritto pubblico con la scelta di un modello di organizzazione di diritto privato per rispondere all’esigenza di assicurare procedure più snelle nella selezione non solo nell’ambito nazionale dei collaboratori, scienziati e ricercatori ”.

IIT è sotto la vigilanza del Ministero dell'Istruzione, dell'Università e della Ricerca e del Ministero dell'Economia e delle Finanze ed è stato istituito con la Legge 326/2003. La Fondazione ha l'obiettivo di promuovere l'eccellenza nella ricerca di base e in quella applicata e di favorire lo sviluppo del sistema economico nazionale. La costruzione dei laboratori iniziata nel 2006 si è conclusa nel 2009.

Lo staff complessivo di IIT conta circa 1440 persone. L’area scientifica è rappresentata da circa l’85% del personale. Il 45% dei ricercatori proviene dall’estero: di questi, il 29% è costituito da stranieri provenienti da oltre 50 Paesi e il 16% da italiani rientrati. Oggi il personale scientifico è composto da circa 60 principal investigators, circa 110 ricercatori e tecnologi di staff, circa 350 post doc, circa 500 studenti di dottorato e borsisti, circa 130 tecnici. Oltre 330 posti su 1400 creati su fondi esterni. Età media 34 anni. 41% donne / 59 % uomini.

Nel 2015 IIT ha ricevuto finanziamenti pubblici per circa 96 milioni di euro (80% del budget), conseguendo fondi esterni per 22 milioni di euro (20% budget) provenienti da 18 progetti europei17 finanziamenti da istituzioni nazionali e internazionali, circa 60 progetti industriali

La produzione di IIT ad oggi vanta circa 6990 pubblicazioni, oltre 130 finanziamenti Europei e 11 ERC, più di 350 domande di brevetto attive, oltre 12 start up costituite e altrettante in fase di lancio. Dal 2009 l’attività scientifica è stata ulteriormente rafforzata con la creazione di dieci centri di ricerca nel territorio nazionale (a Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) e internazionale (MIT ed Harvard negli USA) che, unitamente al Laboratorio Centrale di Genova, sviluppano i programmi di ricerca del piano scientifico 2015-2017.

IIT: the numbers

Istituto Italiano di Tecnologia (IIT) is a public research institute that adopts the organizational model of a private law foundation. IIT is overseen by Ministero dell'Istruzione, dell'Università e della Ricerca and Ministero dell'Economia e delle Finanze (the Italian Ministries of Education, Economy and Finance).  The Institute was set up according to Italian law 326/2003 with the objective of promoting excellence in basic and applied research andfostering Italy’s economic development. Construction of the Laboratories started in 2006 and finished in 2009.

IIT has an overall staff of about 1,440 people. The scientific staff covers about 85% of the total. Out of 45% of researchers coming from abroad 29% are foreigners coming from more than 50 countries and 16% are returned Italians. The scientific staff currently consists of approximately 60 Principal Investigators110 researchers and technologists350 post-docs and 500 PhD students and grant holders and 130 technicians. External funding has allowed the creation of more than 330 positions . The average age is 34 and the gender balance proportion  is 41% female against 59% male.

In 2015 IIT received 96 million euros in public funding (accounting for 80% of its budget) and obtained 22 million euros in external funding (accounting for 20% of its budget). External funding comes from 18 European Projects, other 17 national and international competitive projects and approximately 60 industrial projects.

So far IIT accounts for: about 6990 publications, more than 130 European grants and 11 ERC grants, more than 350 patents or patent applications12 up start-ups and as many  which are about to be launched. The Institute’s scientific activity has been further strengthened since 2009 with the establishment of 11 research nodes throughout Italy (Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) and abroad (MIT and Harvard University, USA), which, along with the Genoa-based Central Lab, implement the research programs included in the 2015-2017 Strategic Plan.