Post-doc position – Brain slice and brain organoid electrophysiology for biohybrid systems to heal epilepsy - [ Postdoc ]

Workplace: Genova, IIT
Added on: 07/11/2018 - Expires on: 15/12/2018

The Laboratory of Enhanced Regenerative Medicine invites applications for 1 post-doc position to conduct brain slice and brain organoid electrophysiology experiments within the context of an exciting visionary cross-disciplinary European project aimed at repairing the epileptic brain by means of functional intelligent biohybrids. This is a high-risk/high-gain visionary project, recently selected for funding within the EU funding scheme FET Proactive (Grant Agreement n°824164 - Acronym: HERMES). The research consortium gathers together experts in tissue/organoid bioengineering, in vitro and in vivo electrophysiology, neuromorphic engineering, machine learning and artificial intelligence. If selected, you will work in a highly stimulating environment promoting close collaboration and cross-fertilization with all these experts.

You must have a degree in Medicine or Biology and a PhD in Neuroscience, Biophysics, Physiology or related disciplines, and a strong track record of hands-on experience with rodent brain slice electrophysiology and in vitro models of epilepsy.

Within the team, you will be responsible for:

  • designing and conducting brain slice and brain organoid (canonical and closed-loop) electrophysiology
  • collect and archive experimental data according to the Data Management Plan
  • analyze and interpret experimental data
  • present results during laboratory meetings, project review meetings and conferences
  • write manuscripts for publication
  • contribute to the preparation of the project periodic reports

Fundamental experimental skills:

  • preparation and maintenance of rodent brain slices for in vitro electrophysiology
  • microelectrode array and/or field potential recording techniques applied to rodent brain slices
  • knowledge of in vitro models of epilepsy (4-aminopyridine and/or high potassium) applied to brain slices

Fundamental personal skills:

  • highly motivated, curious and goal-oriented
  • creative thinking
  • proactive mindset and independent thinking
  • team-oriented collaborative attitute
  • capable of working under pressure in a fast-paced environment
  • excellent written and spoken English

Plus:

  • knowledge of MATLAB programming language and Simulink environment
  • work experience within multi/cross-disciplinary teams
  • FELASA or equivalent personal certification

The application package should include:

  • extended CV, highlighting the names of supervisors and 1-2 lines describing your specific contribution within multi-authored publications
  • letter of motivation (max 1 page)
  • name and contact information of 2-3 referees

The letter of motivation should not be a summary of the CV, but it should describe your long-term research vision, the reason for applying to be part of our team and why you think you are the right candidate to fill this position.

Please send your application by email to This email address is being protected from spambots. You need JavaScript enabled to view it. by December 15th 2018 quoting “Post-doc position – Brain slice electrophysiology for biohybrid systems to heal epilepsy CB 76154” in the subject line.

The position will be available upon funding release from the European Commission, with tentative start date on February 1st 2019.

The salary will be commensurate to your experience and qualification and in line with international standards.

For informal inquiries contact: Dr Gabriella Panuccio: This email address is being protected from spambots. You need JavaScript enabled to view it..

Fondazione Istituto Italiano di Tecnologia - IIT - was founded with the objective of promoting Italy’s technological development and further education in science and technology. In this sense, IIT’s scientific program is based on the combination between basic scientific research and the development of technical applications, a major inspirational principle. Research areas cover scientific topics of high innovative content, representing the most advanced frontiers of modern technology with wide application possibilities in various fields ranging from medicine to industry, from computer science to robotics, life sciences, and nanobiotechnology.

Please note that the data that you provide will be used exclusively for the purpose of  professional profiles’ evaluation and selection, and in order to meet the requirements of Istituto Italiano di Tecnologia.

Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security.

Please also note that, pursuant to articles 15 et. seq. of European Regulation no. 679/2016 (General Data Protection Regulation), you may exercise your rights at any time by contacting the Data Protection Officer (phone +39 010 71781 - email: This email address is being protected from spambots. You need JavaScript enabled to view it.)

Istituto Italiano di Tecnologia is an Equal Opportunity Employer that actively seeks diversity in the workforce.

Contacts

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I numeri di IIT

L’Istituto Italiano di Tecnologia (IIT) è una fondazione di diritto privato - cfr. determinazione Corte dei Conti 23/2015 “IIT è una fondazione da inquadrare fra gli organismi di diritto pubblico con la scelta di un modello di organizzazione di diritto privato per rispondere all’esigenza di assicurare procedure più snelle nella selezione non solo nell’ambito nazionale dei collaboratori, scienziati e ricercatori ”.

IIT è sotto la vigilanza del Ministero dell'Istruzione, dell'Università e della Ricerca e del Ministero dell'Economia e delle Finanze ed è stato istituito con la Legge 326/2003. La Fondazione ha l'obiettivo di promuovere l'eccellenza nella ricerca di base e in quella applicata e di favorire lo sviluppo del sistema economico nazionale. La costruzione dei laboratori iniziata nel 2006 si è conclusa nel 2009.

Lo staff complessivo di IIT conta circa 1440 persone. L’area scientifica è rappresentata da circa l’85% del personale. Il 45% dei ricercatori proviene dall’estero: di questi, il 29% è costituito da stranieri provenienti da oltre 50 Paesi e il 16% da italiani rientrati. Oggi il personale scientifico è composto da circa 60 principal investigators, circa 110 ricercatori e tecnologi di staff, circa 350 post doc, circa 500 studenti di dottorato e borsisti, circa 130 tecnici. Oltre 330 posti su 1400 creati su fondi esterni. Età media 34 anni. 41% donne / 59 % uomini.

Nel 2015 IIT ha ricevuto finanziamenti pubblici per circa 96 milioni di euro (80% del budget), conseguendo fondi esterni per 22 milioni di euro (20% budget) provenienti da 18 progetti europei17 finanziamenti da istituzioni nazionali e internazionali, circa 60 progetti industriali

La produzione di IIT ad oggi vanta circa 6990 pubblicazioni, oltre 130 finanziamenti Europei e 11 ERC, più di 350 domande di brevetto attive, oltre 12 start up costituite e altrettante in fase di lancio. Dal 2009 l’attività scientifica è stata ulteriormente rafforzata con la creazione di dieci centri di ricerca nel territorio nazionale (a Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) e internazionale (MIT ed Harvard negli USA) che, unitamente al Laboratorio Centrale di Genova, sviluppano i programmi di ricerca del piano scientifico 2015-2017.

IIT: the numbers

Istituto Italiano di Tecnologia (IIT) is a public research institute that adopts the organizational model of a private law foundation. IIT is overseen by Ministero dell'Istruzione, dell'Università e della Ricerca and Ministero dell'Economia e delle Finanze (the Italian Ministries of Education, Economy and Finance).  The Institute was set up according to Italian law 326/2003 with the objective of promoting excellence in basic and applied research andfostering Italy’s economic development. Construction of the Laboratories started in 2006 and finished in 2009.

IIT has an overall staff of about 1,440 people. The scientific staff covers about 85% of the total. Out of 45% of researchers coming from abroad 29% are foreigners coming from more than 50 countries and 16% are returned Italians. The scientific staff currently consists of approximately 60 Principal Investigators110 researchers and technologists350 post-docs and 500 PhD students and grant holders and 130 technicians. External funding has allowed the creation of more than 330 positions . The average age is 34 and the gender balance proportion  is 41% female against 59% male.

In 2015 IIT received 96 million euros in public funding (accounting for 80% of its budget) and obtained 22 million euros in external funding (accounting for 20% of its budget). External funding comes from 18 European Projects, other 17 national and international competitive projects and approximately 60 industrial projects.

So far IIT accounts for: about 6990 publications, more than 130 European grants and 11 ERC grants, more than 350 patents or patent applications12 up start-ups and as many  which are about to be launched. The Institute’s scientific activity has been further strengthened since 2009 with the establishment of 11 research nodes throughout Italy (Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) and abroad (MIT and Harvard University, USA), which, along with the Genoa-based Central Lab, implement the research programs included in the 2015-2017 Strategic Plan.