Postdoctoral Fellowship in MR-Guided Hyperthermia - [ Postdoc ]

Workplace: Genova, IIT
Added on: 29/06/2018 - Expires on: 15/08/2018

The Nanotechnology for Precision Medicine Research Line at IIT invites a sharp, enthusiastic, well-trained candidate to work on the development of MR-guided hyperthermia using focused radio frequency. This project involves the development of a new therapeutic modality for neurological and neurodevelopmental disorders, based on novel concepts in focused RF. The goal is to develop algorithms and hardware aiming to non-invasively generate controlled local SAR hotspots and hyperthermia to modulate the permeability of the blood-brain barrier to molecules, nanoparticles and cells.

The ideal candidate will be supported for at least 2 years and will work at the interface of two laboratories: the Decuzzi Lab at the Istituto Italiano di Tecnologia and the Rutt Lab at the Lucas Center for Imaging (Stanford, CA). Decuzzi lab focuses on the design, production and development of nanoparticles for drug delivery and multimodal imaging in a variety of diseases, including cancer, cardiovascular and brain-related disorders. Rutt lab focuses on ultra-high field (7T and above) MRI technology development and applications. Ongoing applications projects include UHF MRI studies of multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, essential tremor, and traumatic brain injury.

Experience and Skills

Minimum:

  • PhD in engineering, physics, biomedical engineering, biophysics, or related discipline
  • Experience with numerical modeling packages such as Sim4Life, CST, FEKO, HFSS, COMSOL
  • Experience with RF coil design and construction: transmit/receive coils, receive arrays, transmit arrays
  • Programming experience (Matlab, other scientific and software development environments)

Desirable:

  • Experience with circuit modeling software like ADS or AWR
  • Experience with CAD modeling using Autocad, Solidworks or similar packages
  • Basic electronics and mechanical workshop experience (e.g. on a CNC mill)

Available Facilities

The Decuzzi and Rutt Labs include the following facilities and key equipment:

Electronics shop: Keysight E5080A VNA, 4 ports; Keysight FieldFox VNA, 2 Ports; Anritsu VNA, 1 port; Keysight DSO 7054B Oscilloscope; Tektronix DPO 4054 Oscilloscope; SPEAG DAK 12 probe

Machine shop: Tormach 770 CNC Mill; Stratasys Fortus 360mc 3D printer

MR scanners: one 7T GE Discovery MR950 (with 8ch pTx), one 3T GE Discovery MR750, one 3T GE Signa Premier, and one 3T GE Signa PET-MR (all 100% available for research, software compatibility between all scanners), as well as multiple animal MR scanners ranging from 3T to 11.7T.

Nanomedicine laboratory: DLS, Multisizer, TEM, SEM, ICP-MS, Clean Room facility with EBL and DLW for nano/microfabrication.

Please apply by August 15, 2018. Please submit your application, including a detailed CV, statement of research experience and interests, and contact information of two referees to: Paolo Decuzzi, ( paolo.decuzzi@iit.it ) quoting: “Postdoctoral Fellowship in MR-Guided Hyperthermia CB 74292”.

 

We inform you that the information you provide will be used solely for the purposes of evaluating and selecting professional profiles in order to meet the requirements of Istituto Italiano di Tecnologia.

Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security.

Please also note that, pursuant to articles 15 et. seq. of European Regulation no. 679/2016 (General Data Protection Regulation), you may exercise your rights at any time by contacting the Data Protection Officer (phone +39 010 71781 - email: dpo@iit.it).

Istituto Italiano di Tecnologia is an Equal Opportunity Employer that actively seeks diversity in the workforce.

Contacts
Paolo Decuzzi
paolo.decuzzi@iit.it
Involved Research lines
Nanotechnology for Precision Medicine

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