Postdoctoral position-Molecular Biologist - [ Postdoc ]

Workplace: Milano, IIT@SEMM
Added on: 28/11/2017 - Expires on: 31/12/2017

A postdoctoral position for a molecular biologist is available in the Computational Epigenomics group at the Center for Genomic Science of Istituto Italiano di Tecnologia (IIT) in Milan, Italy (

This group adopts an interdisciplinary approach based on cutting edge computational and experimental methods to investigate fundamental mechanisms in the epigenetic control of transcriptional regulation. In particular, we study the functional role of the rates of mRNA synthesis, processing and degradation (mRNA dynamics), and their (epi-)genomic determinants.

Starting from robust preliminary data, the selected candidate will lead projects to characterize:

(i) the interplay between chromatin regulation and the m6A epitranscriptome

(ii) the role of this cross-talk for the establishment of mRNA dynamics.

She/he will interact extensively with computational scientists within the group, and will take advantage of a broad network of collaborators (European Epitranscriptomic Network EPITRAN).

Experience with cell cultures, RNA/chromatin biology and high-throughput sequencing based approaches is requested. Interest and skills in bioinformatics are a plus.

The successful candidate will be offered a competitive salary commensurate to qualifications and experience and in line with international standards.

To apply (deadline is December 31, 2017) please send a CV, motivation letter and contacts of two referees to quoting “Post doc Molecular Biologist CB 74700” in the mail subject.

Istituto Italiano di Tecnologia, with its headquarters in Genova, Italy, is a non-profit institution with the primary goal of creating and disseminating scientific knowledge and strengthening Italy’s technological competitiveness. The institute offers state-of-the-art equipment and a top-level interdisciplinary research environment focused on robotics and computer vision, neuroscience, drug discovery, nanoscience and technology.

The Center for Genomic Science is located in the internationally renowned IFOM-IEO cancer research campus, where the candidate will have full access to state of the art facilities for sequencing, proteomics, and computation.

In order to comply with Italian law (art. 23 of Privacy Law of the Italian Legislative Decree n. 196/03), the candidate is kindly asked to give his/her consent to allow IIT to process his/her personal data.

We inform you that the information you provide will be solely used for the purpose of assessing your professional profile to meet the requirements of Istituto Italiano di Tecnologia.

Your data will be processed by Istituto Italiano di Tecnologia, with its headquarters in Genoa, Via Morego 30, acting as the Data Holder, using computer and paper-based means, observing the rules on the protection of personal data, including those relating to the security of data.

Please also note that, pursuant to art. 7 of Legislative Decree 196/2003, you may exercise your rights at any time as a party concerned by contacting the Data Manager.

Istituto Italiano di Tecnologia is an Equal Opportunity Employer that actively seeks diversity in the workforce.

Relevant publications:

de Pretis S .. Pelizzola M. Integrative analysis of RNA polymerase II and transcriptional dynamics upon MYC activation. Genome Research, 2017.

de Pretis S .. Pelizzola M. INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments. Bioinformatics, 2015.

Mukherjee N .. Pelizzola M, Ohler U. Integrative classification of human coding and noncoding genes through RNA metabolism profiles. Nature Structural & Molecular Biology, 2016.

Sabò A*, Kress TR*, Pelizzola M* .. Amati B. Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis. Nature, 2014.



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