Postdoctoral position on the project "Functional and structural plasticity of neurons underlying memory and neurological diseases" - [ Postdoc ]

Workplace: Genova, NSYN@Unige
Added on: 14/06/2019 - Expires on: 15/07/2019

A Junior Postdoctoral position is opening up at the Center for Synaptic Neuroscience and Technology (NSYN) of the Italian Institute of Technology (IIT), at IRCCS San Martino Hospital (Genoa, Italy) ( https://www.iit.it/it/centers/iit-central-research-laboratories/nsyn-unige ) for the study of the functional and structural plasticity underlying memory and disease (see Grasselli et al., Cell Rep 2016 14:2546–2553; Paonessa et al., Proc. Natl. Acad. Sci. USA 2016 113:91-100; Grasselli et al., 2013 Br J Pharmacol 2013 168:502-17; Grasselli et al., PLoS ONE 2011 6: e20791.

The project focuses on the cerebellum as a model brain area and will take advantage of conditional knockout murine strains, in vivo delivery of viral vectors for protein/shRNA expression, confocal microscopy, patch-clamp electrophysiology, optogenetics and time-lapse imaging. It aims at clarifying how modulations of intrinsic excitability affect axonal morphology and how axonal structural plasticity affects circuit function in memory coding and in the pathogenesis of several diseases, including Multiple Sclerosis and Epilepsy.

The candidate should have a relevant PhD, be highly motivated, collaborative, and able to work independently. He/she will have excellent written and verbal communication skills in English. Previous experience in patch-clamp electrophysiology in brain slices and data analysis, stereotactic surgery, immunohistochemistry, confocal microscopy and image analysis will be appreciated.

To apply, please send a motivation letter (including major scientific and technical expertise, achievements, professional goals in the short- and mid-/long-term, and motivations for the interest in the specific call), a CV (including publications) and names and contacts of two referees to Dr. Giorgio Grasselli (giorgio.grasselli@iit.it) and Prof. Fabio Benfenati (fabio.benfenati@iit.it) quoting “Post doc FunStructure CB 77060” in the subject line.

Applications will be reviewed until summer 2019 but for full consideration please apply by July 15, 2019.

Shortlisted applicants will be invited for skype/in-person interview.

The position will start by fall 2019.

Fondazione Istituto Italiano di Tecnologia (IIT) is a public scientific Research Institute established in 2003 by the Italian Ministries of Research and of Economy, in order to promote excellence in basic and applied research and to facilitate technological development. Its research lines range from Neuroscience, Molecular Biology and Pharmacology, to Computer Science, Nanotechnology, Nanomaterials and Robotics. Within IIT, NSYN is a highly interdisciplinary and collaborative center, devoted to the Neurobiology of Disease and to the development of new Neurotechnologies aimed at clinical translation.

Istituto Italiano di Tecnologia is an Equal Opportunity Employer that actively seeks diversity in the workforce.

Please note that the data that you provide will be used exclusively for the purpose of  professional profiles’ evaluation and selection, and in order to meet the requirements of Istituto Italiano di Tecnologia.

Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security.

Please also note that, pursuant to articles 15 et. seq. of European Regulation no. 679/2016 (General Data Protection Regulation), you may exercise your rights at any time by contacting the Data Protection Officer (phone +39 010 71781 - email: dpo[at]iit.it)

Contacts
Fabio Benfenati
fabio.benfenati@iit.it

giorgio.grasselli@iit.it
Involved Research lines
Neuroscience and Smart Materials

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