Contacts: Raul Gainetdinov (Senior researcher), Tatiana Sotnikova (Team leader).
Monoamines, such as dopamine, are key neurotransmitters in the CNS that regulate behavior and motor activity. Their dysfunctions are found in Parkinson’s Disease, schizophrenia and ADHD. By using mutant mice deficient in critical components of dopamine homeostasis and GPCR regulation, we study the mechanisms of dopamine neurotransmission. We are also investigating the role of trace amines and their receptors (TAARs) in neuronal functions.