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People ■ Valter Tucci
Valter Tucci's foto

Valter Tucci

NBT / Neuro Technology

Senior Researcher
Address Via Morego 30
City Genova ZIP Code 16163
Country Italy

Bio

Valter Tucci was born in 1976, in Cosenza (Italy). His main scientific interests are sleep and cognition. To date he has worked in Italy (University of Padua and Bologna), in the USA (MIT and BU) and in the UK (MRC, Harwell).

He graduated in Psychology in 2000, at the University of Padua, studying the cardiovascular changes associated with NREM and REM sleep states in humans. During his Ph.D studies he investigated the physiological and cognitive traits of narcoleptic patients. Then he moved to Boston where he studied sleep physiology and cognitive processes in rhesus monkeys and zebrafish. In 2003 he moved to Oxford (UK). At this time he switched to work on behavioural neurogenetics. He was awarded a Career Development Fellowship by the MRC Mammalian Genetics Unit in Harwell and was then promoted to the post of Investigator Scientist two years later. At MRC Harwell Valter has focused on behavioural/cognitive phenotyping of mouse models, and through the course of the project he has also developed a particular interest in functional genomics. He took the lead in developing new cognitive and neuromuscular screens in mice and has participated to several EU funded consortia in the field of mouse genetics.

In December 2008 Valter Tucci received the Medal “Mente & Cervello” and the Medal of the President of the Republic (Italy) as “Young Investigator”.

Valter Tucci is currently Team Leader of the Neurobehavioural Group at the Italian Institute of Technology (IIT). His research is focused on the analysis of the effects that genetic and epigenetic mechanisms exert on sleep and cognition.

 

Education

  • 2000                 University of Padua (Italy). Master degree in Psychology;
  • 2004                 University of Genoa (Italy). PhD in Sleep Medicine;

Positions and Employment

  • 1998-2000         Teacher Assistant, University of Padua, Laboratory of Sleep Psychophysiology;
  • 2000-2001         Post-degree trainee, University of Bologna, Institute of Neurological Clinic;
  • 2001-2003         Research Fellow, Boston University, Anatomy and Neurobiology Department;
  • 2002-2003         Visiting Scholar, MIT (Boston), Clinical Research Center;
  • 2003-2005         Post-doctoral Scientist, Medical Research Council (Harwell, Oxford),

Mammalian Genetics Unit;

  • 2005-2008         Investigator Scientist, Medical Research Council (Harwell, Oxford),

Mammalian Genetics Unit;

  • 2008-present     Team Leader, IIT (Genova), Neuroscience and Brain Technology Department;

Other Experience and Professional Memberships

  • 2001                 5th Advanced Course of Sleep Medicine (Neuropsychiatric), AIMS;
  • 2006                 Certificate in Management, Institute of Leadership and Management (ILM), London (UK);
  • 2005-2008         Committee, Mutagenesis Management Group, Mary Lyon Centre (Harwell);

Valter Tucci was born in 1976, in Cosenza (Italy). His main scientific interests are sleep and cognition. To date he has worked in Italy (University of Padua and Bologna), in the USA (MIT and BU) and in the UK (MRC, Harwell).

He graduated in Psychology in 2000, at the University of Padua, studying the cardiovascular changes associated with NREM and REM sleep states in humans. During his Ph.D studies he investigated the physiological and cognitive traits of narcoleptic patients. Then he moved to Boston ...

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Selected Publications

  • Lassi G, Ball ST, Maggi S, Colonna G, Nieus T, Cero C, Bartolomucci A, Peters J, Tucci V. Loss of Gnas Imprinting Differentially Affects REM/NREM Sleep and Cognition in Mice. PLoS Genet. 2012 May;8(5):e1002706.
  • Tucci V, Lassi G, Kas MJ. Current Understanding of the Interplay Between Catechol-O-Methyltransferase Genetic Variants, Sleep, Brain Development and Cognitive Performance In Schizophrenia. CNS Neurol Disord Drug Targets. 2012 Apr 4.
  • Iurilli G, Ghezzi D, Olcese U, Lassi G, Nazzaro C, Tonini R, Tucci V, Benfenati F, Medini P. Sound-driven synaptic inhibition in primary visual cortex. Neuron. 2012 Feb 23;73(4):814-28.
  • Tucci V. Sleep, circadian rhythms, and interval timing: evolutionary strategies to time information. Front Integr Neurosci. 2011;5:92. Epub 2012 Jan 4. PubMed PMID: 22319478; PubMed Central PMCID: PMC3250947.
  • Miller G, Neilan M, Chia R, Gheryani N, Holt N, Charbit A, Wells S, Tucci V,Lalanne Z, Denny P, Fisher EM, Cheeseman M, Askew GN, Dear TN. ENU mutagenesis reveals a novel phenotype of reduced limb strength in mice lacking fibrillin 2. PLoS One. 2010 Feb 9;5(2):e9137.
  • Achilli F, Bros-Facer V, Williams HP, Banks GT, AlQatari M, Chia R, Tucci V, Groves M, Nickols CD, Seburn KL, Kendall R, Cader MZ, Talbot K, van Minnen J, Burgess RW, Brandner S, Martin JE, Koltzenburg M, Greensmith L, Nolan PM, Fisher EM. An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. Dis Model Mech. 2009 Jul-Aug;2(7-8):359-73.
  • Tucci V, Plazzi G. Cataplexy: an affair of pleasure or an unpleasant affair? Neurosci Lett. 2009 Jan 30;450(2):90-1.
  • *Mandillo S, *Tucci V, Hölter SM, Meziane H, Banchaabouchi MA, Kallnik M, Lad HV, Nolan PM, Ouagazzal AM, Coghill EL, Gale K, Golini E, Jacquot S, Krezel W, Parker A, Riet F, Schneider I, Marazziti D, Auwerx J, Brown SD, Chambon P, Rosenthal N, Tocchini-Valentini G, Wurst W. Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study. Physiol Genomics. 2008 Aug 15;34(3):243-55.
  • Tucci V, Achilli F, Blanco G, Lad HV, Wells S, Godinho S, Nolan PM. Reaching and grasping phenotypes in the mouse (Mus musculus): a characterization of inbred strains and mutant lines. Neuroscience. 2007 Jul 13;147(3):573-82.
  • Godinho SI, Maywood ES, Shaw L, Tucci V, Barnard AR, Busino L, Pagano M, Kendall R, Quwailid MM, Romero MR, O'neill J, Chesham JE, Brooker D, Lalanne Z, Hastings MH, Nolan PM. The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period. Science. 2007 May 11;316(5826):897-900.
  • Tsai SB, Tucci V, Uchiyama J, Fabian NJ, Lin MC, Bayliss PE, Neuberg DS, Zhdanova IV, Kishi S. Differential effects of genotoxic stress on both concurrent body growth and gradual senescence in the adult zebrafish. Aging Cell. 2007 Apr;6(2):209-24.
  • Eumorphia Consortium. EMPReSS: standardized phenotype screens for functional annotation of the mouse genome. Nat Genet. 2005 Nov;37(11):1155.
  • Yu L, Tucci V, Kishi S, Zhdanova IV. Cognitive aging in zebrafish. PLoS One. 2006 Dec 20;1:e14.
  • Tucci V, Lad HV, Parker A, Polley S, Brown SD, Nolan PM. Gene-environment interactions differentially affect mouse strain behavioral parameters. Mamm Genome. 2006 Nov;17(11):1113-20.
  • Tucci V, Hardy A, Nolan PM. A comparison of physiological and behavioural parameters in C57BL/6J mice undergoing food or water restriction regimes. Behav Brain Res. 2006 Oct 2;173(1):22-9.
  • Tucci V, Stegagno L, Vandi S, Ferrillo F, Palomba D, Vignatelli L, Ferini-Strambi L, Montagna P, Plazzi G. Emotional information processing in patients with narcolepsy: a psychophysiologic investigation. Sleep. 2003 Aug 1;26(5):558-64.
  • Zhdanova IV, Tucci V. Melatonin, Circadian Rhythms, and Sleep. Curr Treat Options Neurol. 2003 May;5(3):225-229.
  • Lassi G, Ball ST, Maggi S, Colonna G, Nieus T, Cero C, Bartolomucci A, Peters J, Tucci V. Loss of Gnas Imprinting Differentially Affects REM/NREM Sleep and Cognition in Mice. PLoS Genet. 2012 May;8(5):e1002706.
  • Tucci V, Lassi G, Kas MJ. Current Understanding of the Interplay Between Catechol-O-Methyltransferase Genetic Variants, Sleep, Brain Development and Cognitive Performance In Schizophrenia. CNS Neurol Disord Drug Targets. 2012 Apr 4.
  • Iurilli G, Ghezzi D, Olcese U, Lassi G, Nazzaro C, Tonini ...

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